rab3A GTP-Binding Protein

The most abundant member of the RAB3 GTP-BINDING PROTEINS. It is involved in calcium-dependent EXOCYTOSIS and is localized to neurons and neuroendocrine cells. This enzyme was formerly listed as EC 3.6.1.47.

Also Known As:

rab3A Protein; smg p25A Protein; GTP-Binding Protein, rab3A; p25A Protein, smg; rab3A GTP Binding Protein; smg25a GTP Binding Protein

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Adam, L: 1 article (12/2000)
2.	Johnson, R: 1 article (12/2000)
3.	Kumar, R: 1 article (12/2000)
4.	Talukder, A H: 1 article (12/2000)
5.	Vadlamudi, R K: 1 article (12/2000)
6.	Wang, R A: 1 article (12/2000)
7.	Blennow, K: 1 article (01/2000)
8.	Bogdanovic, N: 1 article (01/2000)
9.	Davidsson, P: 1 article (01/2000)
10.	Grenfeldt, B: 1 article (01/2000)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 01/01/2000 - "Reduced rab3a protein levels were found in the left thalamus in schizophrenia (0.47 +/- 0.17 vs. 1.00 +/- 0.18; p < 0.0001), while a less marked decrease was found also in the right thalamus (0.75 +/- 0.13 vs. 1.00 +/- 0.09; p < 0.0001). " 01/01/2000 - "Reduced rab3a protein levels were found schizophrenia also in the frontal cortex, hippocampus, gyrus cinguli, and parietal cortex, while no significant differences were found in the temporal cortex, or in cerebellum. "
2.	Neoplasms (Cancer) 11/15/1992 - "The GTP/GDP-binding rab3A protein may be a useful differentiation marker of neuro-endocrine cells in the characterization of undifferentiated neoplasms."
3.	Insulinoma 07/01/1994 - "To determine the expression of the small-molecular-weight guanosine 5'-triphosphate (GTP)-binding protein rab3a in human endocrine pancreatic tissue, total RNA was isolated from five different human insulinomas and from normal human islets. "
4.	Breast Neoplasms (Breast Cancer) 12/01/2000 - "We demonstrated that HRG stimulation of human breast cancer cells and normal breast epithelial cells induces the expression of Rab3A protein and mRNA in a cycloheximide-independent manner. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	RNA (Ribonucleic Acid)
3.	Guanosine Triphosphate (GTP)
4.	Guanosine Diphosphate (GDP)
5.	Guanosine
6.	Cycloheximide (Cicloheximide)
7.	Differentiation Antigens
8.	histidine-rich proteins