|1.||Zhang, Shengnan: 3 articles (10/2011 - 05/2008)|
|2.||Zhong, Nan: 3 articles (10/2011 - 05/2008)|
|3.||Xia, Bin: 3 articles (10/2011 - 05/2008)|
|4.||Jin, Changwen: 3 articles (10/2011 - 05/2008)|
|5.||Lai, Hsing-Yi: 2 articles (02/2014 - 04/2012)|
|6.||Chou, Ya-Wen: 2 articles (02/2014 - 04/2012)|
|7.||Chou, Chi-Yuan: 2 articles (02/2014 - 04/2012)|
|8.||Cheng, Shu-Chun: 2 articles (02/2014 - 04/2012)|
|9.||Wan, David Chi-Cheong: 2 articles (01/2013 - 01/2011)|
|10.||Wong, Kam-Bo: 2 articles (01/2013 - 01/2011)|
|1.||Acquired Immunodeficiency Syndrome (AIDS)
02/23/1990 - "The 11-kD protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. "
06/01/1993 - "In designing HIV protease inhibitors as potential drugs for AIDS therapy, knowledge about what peptide sequences in polyproteins are cleavable by HIV proteases is very useful. "
01/01/1994 - "HIV-1, the causative agent of AIDS, encodes a protease that processes the viral polyproteins into the structural proteins and replicative enzymes found in mature virions. "
|2.||Visceral Leishmaniasis (Kala Azar)
09/01/2015 - "Genetic studies on MERS-CoV have shown that ORF1ab encodes replicase polyproteins and play a foremost role in viral infection. "
01/01/2013 - "The 3C-like protease (3CL(pro)) of coronaviruses is required for proteolytic processing of polyproteins and viral replication, and is a promising target for the development of drugs against coronaviral infection. "
01/01/2011 - "Their 3C-like protease (3CL(pro)), which catalyzes the proteolytic processing of the polyproteins for viral replication, is a potential target for anti-coronaviral infection. "
04/01/2010 - "Thus, during the initial period of SARS-CoV infection, this novel active form AOM(pro) should play a major role in cleaving polyproteins as the protein level is extremely low. "
12/01/2009 - "Under repressive conditions, the ASFV polyproteins pp220 and pp62 are normally processed and virus particles with morphology indistinguishable from that of those produced in a wild-type infection or under permissive conditions are generated. "
|4.||Severe Acute Respiratory Syndrome
05/01/2013 - "The Severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (M(pro)) cleaves two virion polyproteins (pp1a and pp1ab); this essential process represents an attractive target for the development of anti-SARS drugs. "
05/01/2013 - "Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins."
10/01/2011 - "The main protease (M(pro)) of severe acute respiratory syndrome coronavirus (SARS-CoV) plays an essential role in the extensive proteolytic processing of the viral polyproteins (pp1a and pp1ab), and it is an important target for anti-SARS drug development. "
09/01/2010 - "The main protease of the coronavirus causing severe acute respiratory syndrome performs proteolytic processing of the viral polyproteins. "
05/01/2008 - "The main protease (M(pro)) of severe acute respiratory syndrome coronavirus (SARS-CoV) plays an essential role in the extensive proteolytic processing of the viral polyproteins (pp1a and pp1ab), and it is an important target for anti-SARS drug development. "
|5.||Sarcoma (Soft Tissue Sarcoma)
04/15/1983 - "Gag-mos Polyproteins encoded by variants of the Moloney strain of mouse sarcoma virus."
10/01/1982 - "The nucleotide sequences encoding the transforming polyproteins of the Snyder-Theilen and Gardner-Arnstein strains of feline sarcoma virus (FeSV) have been determined. "
09/01/1982 - "A comparison of the intracellular precursor polyproteins of simian sarcoma-associated virus [SiSV(SiAV)] and three human virus isolates: HL23V, HEL12V and A1476V."
09/01/1982 - "Antibody produced by one hybridoma recognizes immunological determinants localized within a feline leukemia virus gag gene structural component (p15) common to polyproteins encoded by each feline sarcoma virus isolate while antibody produced by a second is specific for p30 determinants unique to P170gag-fms. "
09/01/1981 - "The transformation-specific polyproteins of avian sarcoma viruses PRCII, PRCII-p, Fujinami sarcoma virus (FSV), and Esh sarcoma virus (ESV) consist of two domains, one derived from a partial viral gag gene and the other representing an apparently cell-derived insert in the defective viral genome. "
|1.||Peptide Hydrolases (Proteases)
|2.||HIV Protease Inhibitors
|3.||Proteins (Proteins, Gene)
|5.||RNA (Ribonucleic Acid)
|6.||Cysteine Proteases (Cysteine Protease)
|8.||Messenger RNA (mRNA)