Headache Disorders (Headache Syndromes)

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425 relevant articles (50 outcomes, 67 trials/studies) found for this Disease

Description: Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Also Known As:

Headache Syndromes; Headache, Chronic; Chronic Daily Headache; Headache, Intractable; Cephalgia Syndrome; Chronic Daily Headaches; Chronic Headaches; Daily Headache, Chronic; Daily Headaches, Chronic; Headache Disorder; Headache Syndrome; Headache, Chronic Daily; Headaches, Chronic; Headaches, Chronic Daily; Headaches, Intractable; Intractable Headache; Intractable Headaches; Syndrome, Headache; Cephalgia Syndromes; Chronic Headache

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3406

Central Nervous System Diseases: 929

Brain Diseases: 1117

Headache Disorders: 425

Primary Headache Disorders: 85

Secondary Headache Disorders: 13

Related Diseases

1.	Headache (Headaches)
2.	Migraine Disorders (Migraine)
3.	Pain (Aches)
4.	Tension-Type Headache (Tension Headache)
5.	Syndrome

Experts

1.	Silberstein, Stephen D: 3 articles (09/2005 - 06/2002)
2.	Lipton, Richard B: 2 articles (10/2008 - 12/2004)
3.	Mathew, Ninan T: 2 articles (02/2008 - 04/2005)
4.	Swanson, Jerry W: 2 articles (03/2007 - 03/2007)
5.	Amelin, A V: 2 articles (01/2007 - 01/2007)
6.	Tarasova, S V: 2 articles (01/2007 - 01/2007)
7.	Miatleva, M I: 2 articles (01/2007 - 01/2007)
8.	Evers, Stefan: 2 articles (10/2006 - 06/2006)
9.	Peres, Mario F P: 2 articles (04/2006 - 06/2002)
10.	Sarchielli, Paola: 2 articles (12/2005 - 01/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Headache Disorders:

1.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 03/01/2001 - "OBJECTIVE: The purpose of this study was to assess the safety and efficacy of divalproex sodium in the long-term treatment of chronic daily headache" 10/01/1995 - "The efficacy of valproic acid in the treatment of intractable chronic daily headache, unresponsive to traditional prophylactic medications, was examined prospectively in 16 patients" 02/01/2008 - "The objective of the study was to assess the efficacy and tolerability of sodium valproate (VPA) on chronic daily headache (CDH) in a prospective, double-blind, randomized, placebo-controlled trial" 01/01/2003 - "The papers utilized in this study were obtained though Medline searches on valproic acid and divalproex sodium coupled with the various headache disorders" 02/01/1991 - "Thirty patients with persistent chronic daily headache, unresponsive to various combinations of pharmacological and nonpharmacological treatment were selected for an open label study using divalproex sodium" Order ALL the reference details at left...
2.	Antidepressive Agents (Antidepressants)IBA 12/01/2002 - "Antidepressants are effective in the treatment of chronic daily headache and its comorbid depression symptoms, although there is a discrepancy in the treatment response between chronic daily headache and comorbid depression" 07/01/2001 - "CONCLUSION: Antidepressants are effective in preventing chronic headaches" 07/01/2001 - "METHODS: We performed a meta-analysis of English-language, randomized placebo-controlled trials of antidepressants as prophylaxis for chronic headache" 01/01/2007 - "Antidepressants with different action mechanisms in the treatment of chronic daily headache]" 07/01/2001 - "BACKGROUND: Although antidepressants are often used for preventing chronic headache, their effectiveness is uncertain" Order ALL the reference details at left...
3.	Botulinum Toxin Type A (Botox)FDA Link 09/01/2003 - "CONCLUSION: These results suggest that botulinum toxin type A may be an effective and safe prophylactic treatment for a variety of moderate to severe chronic headache types." 04/01/2005 - "OBJECTIVE: The objective of this study was to evaluate the safety and efficacy of botulinum toxin type A (BoNT-A; BOTOX, Allergan, Inc.) for the prophylactic treatment of chronic daily headache (CDH)" 09/01/2005 - "OBJECTIVES: To identify a treatment-responsive population for botulinum toxin type A (BoNTA) and to evaluate the safety and efficacy of 3 different doses of BoNTA as prophylactic treatment of chronic daily headache (CDH)" 06/01/2006 - "A systematic series of controlled trials has led to the identification of a subset of migraineurs with chronic daily headache who obtain demonstrated benefits of botulinum toxin type A over placebo that is maintained with repeated treatments." 09/01/2005 - "Botulinum toxin type A for the prophylactic treatment of chronic daily headache: a randomized, double-blind, placebo-controlled trial." Order ALL the reference details at left...
4.	Amitriptyline (Elavil)FDA LinkGeneric 11/01/1994 - "However, they also show that amitriptyline can only partly alleviate chronic headaches but cannot cure them." 10/01/1994 - "However, they also show that amitriptyline can only partly alleviate chronic headaches but cannot cure them." 01/01/2008 - "Fluvoxamine, amitriptyline and transcranial electrostimulation of the brain in the treatment of chronic daily headache]" 06/01/1990 - "Ritanserin was highly effective in reducing Pain Total Index and analgesic consumption in chronic headache, and its activity was similar to that observed during amitriptyline treatment" 03/01/1981 - "The study pointed out treatments have been effective in reducing frequency, duration and intensity of headache, even though the amitriptyline is more effective in the prophylaxis of chronic headache, whilst amitriptyline plus lithium association seems to be more effective in subacute headache." Order ALL the reference details at left...
5.	Dihydroergotamine (Agit)FDA LinkGeneric 03/01/1992 - "Renewed interest in its use has been kindled by research in receptor pharmacology and by efficacy of DHE-45 in breaking the cycle of chronic daily headache" 05/01/1998 - "In-patient treatment of chronic daily headache using dihydroergotamine: a long-term follow-up study." 03/01/1997 - "Continuous intravenous dihydroergotamine in the treatment of intractable headache." 05/01/1996 - "Side effects associated with administration of repetitive intravenous dihydroergotamine (DHE) were prospectively studied in 72 patients with chronic daily headache who were hospitalized in a dedicated inpatient headache treatment program" 10/01/1998 - "Medications which provide symptomatic relief from headache can transform episodic migraine into chronic daily headache by propagating the daily headache, causing "rebound." It is possible to restore the episodic migraine pattern by using an inpatient course of intravenous dihydroergotamine" Order ALL the reference details at left...
6.	Indomethacin (Indometacin)FDA LinkGeneric 05/01/1998 - "We report a new case which responded well to indomethacin, and suggest that indomethacin may be used as an alternative treatment in this rare headache syndrome of the elderly." 08/01/2002 - "Where patients with chronic daily headaches are unresponsive to standard therapies, a trial of indomethacin is warranted." 02/01/2004 - "Each category can be differentiated clinically and by the extent to which the individual headache disorders respond to indomethacin" 02/01/2004 - "Indomethacin-responsive headache syndromes." 03/01/2001 - "Although uncommon conditions, successful treatment depends on recognition of these indomethacin-responsive headache syndromes." Order ALL the reference details at left...
7.	tizanidine (Zanaflex)FDA LinkGeneric 03/01/2003 - "Tizanidine is not a cure for chronic daily headache." 01/01/2003 - "One well controlled trial, conducted as a follow-up to an open-label trial in the preventive treatment of chronic daily headache, reported tizanidine as having a statistically significant benefit over placebo" 01/01/2003 - "Open trials of tizanidine have shown it to be useful in chronic headache" 06/01/2002 - "Chronic daily headache prophylaxis with tizanidine: a double-blind, placebo-controlled, multicenter outcome study." 04/01/2001 - "CONCLUSIONS: The results provide preliminary support for the efficacy, safety, and tolerability of tizanidine in the prophylaxis of chronic daily headache." Order ALL the reference details at left...
8.	Anti-Bacterial Agents (Antibiotics)IBA 02/01/2008 - "CASE REPORT: A 77-year-old woman with a past medical history of rhinorrhoea and chronic headache was admitted for a verrucous and erythematous lesion on her right cheek, evolving for two months with incomplete remission after numerous antibiotics" 10/01/2006 - "He was immediately treated with several antibiotics, then his clinical symptoms improved, although intractable headache relapsed after withdrawal of the initial therapy" Order ALL the reference details at left...
9.	Botulinum Toxins (Botulinum Toxin)IBA 01/01/2004 - "Botulinum toxin A for chronic daily headache: a randomized, placebo-controlled, parallel design study." 01/01/2008 - "Evidence based medicine on the use of botulinum toxin for headache disorders." 03/01/2007 - "Botulinum toxin A for prophylaxis of chronic daily headaches." 06/01/2006 - "Status on the use of botulinum toxin for headache disorders." 03/01/2006 - "Regarding botulinum toxin for the prophylaxis of chronic daily headache." Order ALL the reference details at left...
10.	LithiumIBA 06/01/2004 - "These headache syndromes have been shown to respond to melatonin and lithium therapy, both of which have an indirect impact on the sleep-wake cycle" 03/01/1981 - "The study pointed out treatments have been effective in reducing frequency, duration and intensity of headache, even though the amitriptyline is more effective in the prophylaxis of chronic headache, whilst amitriptyline plus lithium association seems to be more effective in subacute headache." 03/01/1979 - "The results obtained seem very favourable however the therapeutic efficiency of Lithium salts, also observed in neuralgic-vasomotor syndromes (Charlin, Sluder) and in some forms of chronic headache, seems to indicate a relatively unspecific mechanism of action" 11/01/1992 - "Due to the possible involvement of endothelin in headache disorders, the objective of this study was to verify the effects of lithium and cyclooxygenase inhibitors (indomethacin, acetylsalicylic acid and naproxen) on endothelin-1 (ET-1)-induced contractions in isolated human temporal arteries and porcine ophthalmic arteries" Order ALL the reference details at left...

Therapies and Procedures

1.	Biofeedback (Psychology) (Biofeedback) 10/01/1992 - "Long-term efficacy of combined relaxation: biofeedback treatments for chronic headache." 11/01/1995 - "The first study evaluated the effectiveness of a combined nonpharmacological treatment (CT) consisting of relaxation, skin-warming biofeedback, and physical therapy for pregnant women with chronic headaches" 01/01/1986 - "Three studies of the psychologic changes in chronic headache patients associated with biofeedback and relaxation therapies." 09/01/2008 - "Biofeedback treatment for headache disorders: a comprehensive efficacy review." 12/01/2001 - "Sixteen patients with chronic daily headache (HA) of moderate to severe intensity received 20 sessions of self-regulatory treatment including progressive muscle relaxation, thermal biofeedback, and cognitive stress coping therapy" Order ALL the reference details at left...
2.	Spinal Manipulation 09/01/2001 - "Efficacy of spinal manipulation for chronic headache: a systematic review." 07/01/2003 - "The effectiveness of spinal manipulation for the treatment of headache disorders: a systematic review of randomized clinical trials." 10/01/2002 - "The effectiveness of spinal manipulation for the treatment of headache disorders: a systematic review of randomized clinical trials." 07/01/1994 - "These findings would suggest that further study of upper cervical manipulation for the treatment of chronic headaches with upper cervical joint dysfunction in a randomized, controlled clinical trial is needed." 10/01/2002 - "To carry out a systematic review of the literature examining the effectiveness of spinal manipulation for the treatment of headache disorders, computerized literature searches were carried out in Medline, Embase, Amed and CISCOM" Order ALL the reference details at left...
3.	Nerve Block (Nerve Blocks) 10/01/2005 - "Our four patients with chronic headaches responded well to occipital nerve blocks" 03/01/2007 - "The objective of this study was to determine if response to occipital nerve block (ONB) predicts response to ONS in patients with chronic, medically intractable headaches" 01/01/2001 - "Re: A descriptive study of 100 patients undergoing palliative nerve blocks for chronic intractable headache and neckache" 10/01/2001 - "A patient with chronic daily headaches developed overt signs of Cushing syndrome during treatment with serial occipital nerve block injections" Order ALL the reference details at left...
4.	Aftercare (After-Treatment) 02/01/1997 - "To assess the clinical and personality characteristics of patients with chronic daily headache before and after treatment, 20 patients were examined and the Minnesota Multiphasic Personality Inventory (MMPI [Italian 356-item abbreviated version]) and the Strait and Trait Anxiety Index 1,2 (STAI) administered" 05/01/2007 - "Improvement of chronic headache after treatment of unruptured intracranial aneurysms." 11/01/1995 - "However, over 30% of patients with chronic headache and other symptoms of sleep apnea have significant improvement in headache after treatment of sleep apnea." 11/01/2002 - "In studies of migraine headache, chronic daily headache (more than 15 days of headache per month), tension-type headache, and post-whiplash headache, patients have reported decreased pain after treatment with botulinum toxin type A" Order ALL the reference details at left...
5.	Hypnosis (Mesmerism) 09/01/1994 - "The aims of this study were to (a) investigate the efficacy of autogenic training (AT) and cognitive self-hypnosis training (CSH) for the treatment of chronic headaches in comparison with a waiting-list control (WLC) condition, (b) investigate the influence of subject recruitment on treatment outcome and (c) explore whether the level of hypnotizability is related to therapy outcome" 12/01/1980 - "Data were collected before and after hypnosis on the nature and intensity of the patient's acute pain and anxiety during bone marrow aspirations, chronic headache and backache, nausea and vomiting during chemotherapy, anorexia, and the discomfort associated with spiking temperatures" Order ALL the reference details at left...

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