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L-Type Calcium Channels (Dihydropyridine Receptor)

Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
Also Known As:
Dihydropyridine Receptor; L-Type Calcium Channel; Calcium Channel, L-Type; Calcium Channels, L-Type; L-Type VDCC; L-Type VDCC alpha-2 Subunit; L-Type VDCC beta Subunit; L-Type VDCC delta Subunit; L-Type VDCC gamma Subunit; L-Type Voltage-Dependent Calcium Channels; Calcium Channels, L Type; Calcium Channels, Long-Lasting; L Type Calcium Channel; L Type Calcium Channels; L Type VDCC; L Type VDCC alpha 1 Subunit; L Type VDCC alpha 2 Subunit; L Type VDCC beta Subunit; L Type VDCC delta Subunit; L Type VDCC gamma Subunit; L Type Voltage Dependent Calcium Channels; Long Lasting Calcium Channels; Receptor, Dihydropyridine; VDCC, L-Type; Dihydropyridine Receptors; L-Type VDCC alpha-1 Subunit; Long-Lasting Calcium Channels; Receptors, Dihydropyridine
Networked: 434 relevant articles (22 outcomes, 50 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zamponi, Gerald W: 3 articles (07/2014 - 01/2012)
2. Higaki, Jitsuo: 3 articles (12/2013 - 06/2006)
3. Silverman, Richard B: 3 articles (07/2013 - 01/2012)
4. Luan, Chi-Hao: 3 articles (07/2013 - 01/2012)
5. Kang, Soosung: 3 articles (07/2013 - 01/2012)
6. Cooper, Garry: 3 articles (07/2013 - 01/2012)
7. Porreca, Frank: 3 articles (06/2012 - 09/2003)
8. Kim-Mitsuyama, Shokei: 3 articles (12/2011 - 01/2005)
9. Tao, Jin: 3 articles (09/2007 - 10/2005)
10. Hess, Ellen J: 3 articles (01/2006 - 01/2003)

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Related Drugs and Biologics

1. Nifedipine (Adalat)
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3. N-Type Calcium Channels (N-Type Calcium Channel)
4. Nimodipine (Modus)
5. Calcium Channel Blockers (Blockers, Calcium Channel)
6. 1,4-dihydropyridine (dihydropyridine)
7. Calcium Channels (Calcium Channel)
8. Amlodipine (Norvasc)
9. cilnidipine
10. Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)

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2. Positive-Pressure Respiration (PEEP)
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4. Topical Administration
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