|1.||Müller, Christian P: 2 articles (10/2014 - 10/2014)|
|2.||Fernandes, Cathy: 2 articles (10/2014 - 10/2014)|
|3.||Schumann, Gunter: 2 articles (10/2014 - 10/2014)|
|4.||Kornhuber, Johannes: 2 articles (10/2014 - 10/2014)|
|5.||Easton, Alanna C: 2 articles (10/2014 - 10/2014)|
|6.||Santos, Eugenio: 2 articles (10/2014 - 10/2014)|
|7.||Desrivières, Sylvane: 2 articles (10/2014 - 10/2014)|
|8.||Rotter, Andrea: 2 articles (10/2014 - 10/2014)|
|9.||Biermann, Teresa: 2 articles (10/2014 - 10/2014)|
|10.||Fernández-Medarde, Alberto: 2 articles (10/2014 - 10/2014)|
12/01/2008 - "The guanine nucleotide exchange factor, C3G regulates differentiation and survival of human neuroblastoma cells."
01/01/2011 - "TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells."
12/01/2008 - "Human neuroblastoma cells, IMR-32 induced to differentiate by serum starvation or by treatment with nerve growth factor (NGF) or forskolin showed enhanced C3G protein levels. "
01/01/2004 - "Immunohistochemical staining revealed prominent C3G protein in the cytoplasm of cancer cells, associated with faint staining at the nucleolar membrane, but C3G was not detectable in normal bronchial mucoepithelial cells or in broncholoalveolar cells of the bronchial/bronchiolar ducts or alveoli. "
01/01/1991 - "Increases (P less than 0.05) in GH release were observed in the presence of (1) GRF; (2) the adenylyl cyclase stimulator, forskolin; (3) a cAMP analog, 8-bromo-cAMP; (4) the phosphodiesterase inhibitor 3-isobutyl-l-methyl-xanthine (IBMX) combined with GRF; (5) a tumor-promoting phorbol ester and protein kinase C activator, phorbol 12-myristate, 13-acetate (PMA); (6) a diacylglycerol analog, 1,2-dioctanoyl-glycerol (DiC8); and (7) a calcium ionophore, A23187, alone and in combination with PMA. "
08/01/2010 - "Together, these findings suggest (1) the existence of regulatory mechanisms resulting in disease-related up-regulation of C3G in GMC and (2) that an increase in the C3G protein level may contribute to the resolution stage of mesangioproliferative glomerulonephritis by reducing GMC sensitivity to ET-1, modulating cellular motility, and actin dynamics."
01/01/2009 - "We found that expression of C3G protein was upregulated in glomerular epithelial cells in an experimental model of accelerated anti-GBM antibody-induced glomerulonephritis expression. "
01/01/2009 - "The guanine nucleotide exchange factor C3G, along with the CrkII adaptor protein, mediates GTP activation of the small GTPase proteins Rap1 and R-Ras, facilitating their activation of downstream signaling pathways, which had been found to be important in the pathogenesis of glomerulonephritis. "
|4.||Alcoholism (Alcohol Abuse)
|2.||Non-Receptor Type 2 Protein Tyrosine Phosphatase
|3.||Small Interfering RNA (siRNA)
|4.||Nerve Growth Factor (NGF)
|5.||ras-GRF1 (ras GRF1)
|6.||GTP Phosphohydrolases (GTPases)
|7.||8-Bromo Cyclic Adenosine Monophosphate (8 Bromo Cyclic Adenosine Monophosphate)
|8.||1-Methyl-3-isobutylxanthine (1 Methyl 3 isobutylxanthine)
|9.||Proteins (Proteins, Gene)
|10.||Protein Kinase C