Exopeptidases (Exopeptidase)

01/01/2016 - "In particular, we investigate the E2-induced expression and cellular distribution of DPP III monozinc exopeptidase, a member of the Nrf-2/Keap-1 pathway, upon hyperoxia treatment. "
01/01/2016 - "Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo."

04/01/2006 - "Differential exoprotease activities confer tumor-specific serum peptidome patterns."
01/01/2006 - "Differential exoprotease activities confer tumor-specific serum peptidome patterns."
12/01/2010 - "Various studies exploring the potential of the low-molecular-weight serum peptidome have identified proteolytic cleavage products of inter-α-trypsin inhibitor heavy chain-4 (ITIH(4)) as potential markers for different types of cancer, presumably generated by tumor-associated exoproteases. "
01/01/2016 - "CarboxypeptidaseA4 (CPA4) is a zinc-containing exopeptidases, and its aberrant expression has been implicated in cancer development and progression. "
01/01/2008 - "APN is an important zinc dependent metallo-exopeptidase; it has been considered as a suitable target for anti-cancer drug design. "

01/01/2021 - "Nonetheless, exoprotease-deficient mutants were as virulent as the wild-type strain in a murine model of systemic infection, in Caenorhabditis elegans and in Galleria mellonella. "
05/01/1989 - "We examined the effect of a serratial exoprotease on the pathogenesis of influenza virus infection in mice as a model of complicated respiratory infection by bacteria and virus in humans. "
01/01/1985 - "It has been shown that the production of high levels of exoprotease can alter the apparent type of the strain by rendering it insensitive to infection by a number of bacteriophages. "
06/01/1984 - "aeruginosa exoproteases as virulence factors in the pathogenesis of infections caused by this microorganism."
10/17/2023 - "Among the most studied virulence factors susceptible to cheating are siderophores and exoproteases, with several studies in vitro and some in animal infection models. "

01/01/2023 - "This study assesses the clinical relevance of dipeptidyl peptidase 4 (DPP4) membrane exopeptidase as a biomarker of inflammatory bowel disease (IBD). "

08/06/2010 - "In this study, we confirmed that the exoprotease breakdown peptides, ITIH4 (666-687]) and des-Arg(9)-bradykinin, differed between breast cancer cases and controls, supporting the potential of degradome markers for the diagnosis of breast cancer."
08/06/2010 - "In this study, we investigated the discriminative value of six peptides that were previously proposed to be generated by breast cancer specific exoproteases: bradykinin, des-Arg(9)-bradykinin, Hyp(3)-bradykinin, and fragments of fibrinogen alpha-chain (Fib-alpha ([605-629])), complement component 4a (C4a ([1337-1350])), and interalpha trypsin inhibitor heavy chain 4 (ITIH4 ([666-687])). "