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I-kappa B Proteins (I kappa B)

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Also Known As:
I kappa B; I-kappa B; IkB DNA-Binding Proteins; I kappa B Proteins; IkB DNA Binding Proteins
Networked: 131 relevant articles (3 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Dou, Q Ping: 3 articles (01/2008 - 07/2002)
2. Zhang, Jun: 2 articles (03/2011 - 10/2003)
3. Heneka, Michael T: 2 articles (01/2004 - 08/2002)
4. Smith, David M: 2 articles (09/2003 - 07/2002)
5. Kazi, Aslamuzzaman: 2 articles (09/2003 - 07/2002)
6. Feinstein, Douglas L: 2 articles (08/2002 - 08/2002)
7. Simons, M: 2 articles (12/2001 - 08/2000)
8. Sato, K: 2 articles (12/2001 - 08/2000)
9. Gao, Y: 2 articles (12/2001 - 08/2000)
10. Post, M J: 2 articles (12/2001 - 08/2000)

Related Diseases

1. Neoplasms (Cancer)
2. Shock
3. Septic Shock (Toxic Shock Syndrome)
4. Infection
5. Anoxia (Hypoxia)

Related Drugs and Biologics

1. NF-kappa B (NF-kB)
2. Phosphotransferases (Kinase)
3. Messenger RNA (mRNA)
4. I-kappa B Kinase
5. DNA (Deoxyribonucleic Acid)
6. tax Gene Products (tax Gene Product)
7. Collagen Type II (Type II Collagen)
8. Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)
9. Casein Kinase II (Casein Kinase 2)
10. HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Stents