|1.||Brambilla, Riccardo: 6 articles (06/2015 - 10/2009)|
|2.||Fasano, Stefania: 5 articles (06/2015 - 10/2009)|
|3.||D'Antoni, Angela: 3 articles (06/2015 - 10/2009)|
|4.||Indrigo, Marzia: 2 articles (06/2015 - 12/2010)|
|5.||Cerovic, Milica: 2 articles (01/2015 - 12/2010)|
|6.||Yamada, Ryo: 2 articles (11/2014 - 11/2013)|
|7.||Gotoh, Norimoto: 2 articles (11/2014 - 11/2013)|
|8.||Yoshimura, Nagahisa: 2 articles (11/2014 - 11/2013)|
|9.||Nagahama Study Group: 2 articles (11/2014 - 11/2013)|
|10.||Nakanishi, Hideo: 2 articles (11/2014 - 11/2013)|
01/01/2015 - "All eligible studies investigating the association between the RASGRF1 gene and high myopia listed in PubMed, EMBASE, the Cochrane Library, Web of Science, and the China Biologic Medical Database were retrieved. "
02/01/2015 - "Two recent large-scale genome-wide association studies identified significant associations between myopia and single nucleotide polymorphisms (SNPs) near the PRSS56, BMP3, KCNQ5, LAMA2, TOX, TJP2, RDH5, ZIC2, RASGRF1, GJD2, RBFOX1, and SHISA6 genes. "
01/01/2015 - "The RASGRF1 gene may play a role in the development of high myopia, especially in Asians. "
01/01/2015 - "Carriers of the rs8027411 G allele in the RASGRF1 gene may be at a lower risk of high myopia in Chinese and Japanese populations. "
01/01/2015 - "The results indicated that RASGRF1 rs8027411 was significantly associated with high myopia in Chinese and Japanese populations. "
|2.||Temporal Lobe Epilepsy
02/01/2013 - "The aim of this study was to measure Ras-GRF1 expression in brain tissue of patients with drug-refractory temporal lobe epilepsy (TLE) and lithium chloride-pilocarprine kindled rats using double-label immunofluorescence, immunohistochemistry and Western blotting and to discuss the possible role of Ras-GRF1 in TLE. "
06/01/2015 - "Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia."
12/14/2010 - "Furthermore, in a nonhuman primate model of LID, lentiviral vectors expressing dominant negative forms of Ras-GRF1 caused a dramatic reversion of dyskinesia severity leaving intact the therapeutic effect of L-dopa. "
12/14/2010 - "Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia."
06/01/2015 - "Moreover, striatal injection of LV-shRNA/Ras-GRF1 attenuated dyskinesia development and ERK-dependent signaling, whereas LV-shRNA/Ras-GRF2 was without effect, ruling out the involvement of Ras-GRF2 in LID expression. "
01/15/2015 - "Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia."
02/01/2013 - "Ras-GRF1 expression in epileptic rats was already reduced at 1 day post-seizures, then gradually decreased during the latent period and reached a minimum level during the chronic phase. "
12/01/2001 - "In addition, we showed that mice lacking Ras-GRF1 displayed a higher seizure susceptibility following acute administration of convulsant drugs. "
|5.||Melanoma (Melanoma, Malignant)
05/18/2007 - "Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells."
01/01/2009 - "Recently, expression and post-translational modification of Ras guanine nucleotide releasing factor 1 (RasGRF1) was found to contribute to spontaneous MMP production in melanoma cancer cells. "
|2.||Levodopa (L Dopa)
|3.||ras-GRF1 (ras GRF1)
|5.||snRNP Core Proteins
|6.||Small Interfering RNA (siRNA)
|7.||Matrix Metalloproteinase 9 (Gelatinase B)
|8.||Guanine Nucleotide-Releasing Factor 2
|9.||ras Guanine Nucleotide Exchange Factors
|10.||Pepsinogen A (Pepsinogen)