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Chronic Progressive Multiple Sclerosis

A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)
Also Known As:
Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Primary Progressive; Multiple Sclerosis, Secondary Progressive; Primary Progressive Multiple Sclerosis; Progressive Relapsing Multiple Sclerosis; Remittent Progressive Multiple Sclerosis; Secondary Progressive Multiple Sclerosis; Multiple Sclerosis, Progressive Relapsing; Multiple Sclerosis, Remittent Progressive
Networked: 769 relevant articles (56 outcomes, 160 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Multiple Sclerosis
2. Relapsing-Remitting Multiple Sclerosis
3. Chronic Progressive Multiple Sclerosis
4. Atrophy
5. Inflammation (Inflammations)

Experts

1. Kappos, Ludwig: 18 articles (09/2022 - 12/2010)
2. Hartung, Hans-Peter: 18 articles (12/2020 - 12/2002)
3. Giovannoni, Gavin: 16 articles (09/2022 - 09/2003)
4. Wolinsky, Jerry S: 13 articles (10/2021 - 06/2004)
5. Montalban, Xavier: 12 articles (10/2021 - 06/2004)
6. Arnold, Douglas L: 11 articles (09/2022 - 01/2017)
7. Bar-Or, Amit: 11 articles (09/2022 - 09/2004)
8. Gold, Ralf: 10 articles (09/2022 - 09/2007)
9. Chataway, Jeremy: 10 articles (07/2022 - 07/2010)
10. Miller, David H: 10 articles (03/2016 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chronic Progressive Multiple Sclerosis:
1. Interferon-betaIBA
2. ocrelizumabIBA
3. siponimodIBA
4. Mitoxantrone (Novantrone)FDA LinkGeneric
5. Interferon beta-1b (Betaseron)FDA Link
6. Interferon beta-1aFDA Link
7. Cyclophosphamide (Cytoxan)FDA LinkGeneric
8. InterferonsIBA
9. Natalizumab (Tysabri)FDA Link
10. CladribineFDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Transplantation
3. Plasma Exchange
4. Drug Therapy (Chemotherapy)
5. Lymphatic Irradiation