Femoral Neuropathy

Disease involving the femoral nerve. The femoral nerve may be injured by ISCHEMIA (e.g., in association with DIABETIC NEUROPATHIES), nerve compression, trauma, COLLAGEN DISEASES, and other disease processes. Clinical features include MUSCLE WEAKNESS or PARALYSIS of hip flexion and knee extension, ATROPHY of the QUADRICEPS MUSCLE, reduced or absent patellar reflex, and impaired sensation over the anterior and medial thigh.

Also Known As:

Bernhardt-Roth Syndrome; Femoral Nerve Dysfunction; Femoral Neuritis; Lateral Femoral Cutaneous Nerve Entrapment; Meralgia Paresthetica; Bernhardt Roth Syndrome; Femoral Mononeuropathies; Femoral Nerve Disease; Femoral Nerve Dysfunctions; Femoral Neuritides; Femoral Neuropathies; Nerve Disease, Femoral; Nerve Diseases, Femoral; Nerve Dysfunction, Femoral; Neuritis, Femoral; Femoral Mononeuropathy; Femoral Nerve Diseases; Mononeuropathy, Femoral; Neuropathy, Femoral

Networked: 226 relevant articles (6 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 14178
- Neuromuscular Diseases: 2005
  - Peripheral Nervous System Diseases: 11383
    - Mononeuropathies: 552
      - Femoral Neuropathy: 226

Related Diseases

1.	Hematoma
2.	Wound Infection (Wound Infections)
3.	Pain (Aches)
4.	Paresthesia (Dysesthesia)
5.	Hemorrhage

Experts

1.	de Ruiter, Godard C W: 5 articles (01/2021 - 10/2012)
2.	Kloet, Alfred: 3 articles (07/2015 - 10/2012)
3.	Ducic, Ivica: 3 articles (03/2011 - 10/2005)
4.	Schwaiger, Karl: 2 articles (04/2022 - 08/2018)
5.	Spinner, Robert J: 2 articles (01/2021 - 04/2014)
6.	Arends, Samuel: 2 articles (01/2020 - 09/2016)
7.	Harbaugh, Kimberly: 2 articles (10/2017 - 01/2017)
8.	Rizk, Elias: 2 articles (10/2017 - 01/2017)
9.	Wurzer, Johannes A L: 2 articles (01/2015 - 10/2012)
10.	Martinoli, Carlo: 2 articles (10/2011 - 11/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Femoral Neuropathy:

1.	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 08/01/2000 - "Conservative management consisting of local analgesics, steroids, nonsteroidal antiinflammatories, rest, and reduction or elimination of aggravating factors yielded long-lasting improvement in five patients with meralgia paresthetica. " 06/01/2012 - "A 23-year-old female with an 18-month history of left anterolateral thigh paresthesias and burning pain consistent with meralgia paresthetica was referred to our clinic after failing trials of physical therapy, nonsteroidal anti-inflammatories, gabapentin, and amitriptyline. "
2.	Topiramate (Topamax)FDA LinkGeneric 01/01/2010 - "First-line treatment should be conservative, but topiramate may be useful for the treatment of meralgia paresthetica, although broader studies are needed to evaluate its true effectiveness in this pathological condition."
3.	Glucose (Dextrose)FDA LinkGeneric 01/01/2020 - "Efficacy of Nerve Hydrodissection With 5% Dextrose in Chronic Meralgia Paresthetica." 07/01/1991 - "[Femoral neuropathy, diabetes mellitus, reduced glucose tolerance. "
4.	SteroidsIBA 08/01/2000 - "Conservative management consisting of local analgesics, steroids, nonsteroidal antiinflammatories, rest, and reduction or elimination of aggravating factors yielded long-lasting improvement in five patients with meralgia paresthetica. "
5.	Analgesics (Analgesic Drugs)IBA 08/01/2000 - "Conservative management consisting of local analgesics, steroids, nonsteroidal antiinflammatories, rest, and reduction or elimination of aggravating factors yielded long-lasting improvement in five patients with meralgia paresthetica. "
6.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2020 - "We found no objective evidence for benefit from nerve stimulator-guided injection with corticosteroids in meralgia paresthetica, although this study is limited by a small sample size. " 01/01/2023 - "Ultrasound-Guided Treatment of Meralgia Paresthetica: With or Without Corticosteroid? " 09/01/2001 - "Idiopathic meralgia paresthetica usually improves with nonoperative modalities, such as removal of compressive agents, nonsteroidal anti-inflammatory drugs, and, if necessary, local corticosteroid injections. "
7.	Methylprednisolone FDA LinkGeneric 01/01/2020 - "Meralgia paresthetica: Nerve stimulator-guided injection with methylprednisolone/lidocaine, a double-blind randomized placebo-controlled study."
8.	Lidocaine (Xylocaine)FDA LinkGeneric 01/01/2020 - "Meralgia paresthetica: Nerve stimulator-guided injection with methylprednisolone/lidocaine, a double-blind randomized placebo-controlled study."
9.	Amitriptyline (Elavil)FDA LinkGeneric 06/01/2012 - "A 23-year-old female with an 18-month history of left anterolateral thigh paresthesias and burning pain consistent with meralgia paresthetica was referred to our clinic after failing trials of physical therapy, nonsteroidal anti-inflammatories, gabapentin, and amitriptyline. "
10.	Gabapentin (Neurontin)FDA LinkGeneric 06/01/2012 - "A 23-year-old female with an 18-month history of left anterolateral thigh paresthesias and burning pain consistent with meralgia paresthetica was referred to our clinic after failing trials of physical therapy, nonsteroidal anti-inflammatories, gabapentin, and amitriptyline. "

Therapies and Procedures

1.	Conservative Treatment 01/01/2020 - "Conservative Treatment Versus Ultrasound-Guided Injection in the Management of Meralgia Paresthetica: A Randomized Controlled Trial." 10/01/2008 - "We present the case of a healthy 15-year-old boy with a femoral neuropathy due to an iliacus haematoma which resolved following conservative treatment." 07/01/2005 - "An implanted spinal cord stimulator may be an ideal treatment for intractable meralgia paresthetica after conservative treatments have failed because it is not destructive and can always be explanted without significant permanent adverse effects." 07/01/2005 - "To present a case of intractable meralgia paresthetica in which conservative treatment options failed but which was successfully treated with a spinal cord stimulator. " 07/01/2005 - "The majority of patients with meralgia paresthetica respond well to conservative treatment. "
2.	Decompression 04/01/2022 - "[Decompression of the lateral femoral cutaneous nerve of the thigh : Treatment of meralgia paresthetica]." 12/01/2018 - "Dynamic decompression of the lateral femoral cutaneous nerve to treat meralgia paresthetica: technique and results." 04/13/2018 - "After studying and publishing data on the anatomical feasibility of LFCN transposition, the author presents here the first case series of patients who underwent LFCN transposition.METHODSNineteen patients with meralgia paresthetica were treated in the Department of Neurological Surgery at University of Wisconsin between 2011 and 2016; 4 patients underwent simple decompression, 5 deep decompression, and 10 medial transposition. " 03/01/2011 - "Modified approach for lateral femoral cutaneous nerve decompression in patients with meralgia paresthetica." 04/01/2007 - "To review the results of conservative and surgical treatment of meralgia paresthetica (MP), with particular reference to the use of a simple clinical test for diagnosing this condition and the outcome of primary nerve decompression surgery. "
3.	Surgical Decompression 08/01/2018 - "Surgical decompression of the lateral femoral cutaneous nerve (LFCN) for Meralgia paresthetica treatment: Experimental or state of the art? " 07/01/2011 - "We describe a rare anatomical variation of the lateral femoral cutaneous nerve (LFCN) in a 29-year old female patient discovered during a surgical decompression of the LFCN for meralgia paresthetica. " 12/01/1995 - "Meralgia paresthetica: etiology, diagnosis, and outcome of surgical decompression." 05/01/2023 - "For idiopathic meralgia paresthetica, the results of surgical decompression have never been compared to those of neurectomy in a randomized setup. " 06/01/2005 - "The right hematoma was larger than the left one and caused more severe femoral neuropathy, but improved gradually without surgical decompression. "
4.	Musculoskeletal Manipulations (Manipulative Therapy) 01/01/2006 - "To present a case of a pregnant patient with meralgia paresthetica who improved using manual therapy and exercise procedures. " 01/01/2006 - "A manual therapy and exercise approach to meralgia paresthetica in pregnancy: a case report."
5.	Chest Tubes (Chest Tube) 01/01/2020 - "Complications in the MIS group included 1 screw misplacement requiring revision, 2 postoperative femoral neuropathies (one of which improved), 1 return to surgery for inadequate posterior decompression, 4 pneumothoraces requiring chest tube placement, and 1 posterior wound infection. "