|1.||Tachezy, Michael: 8 articles (10/2014 - 10/2011)|
|2.||Zander, Hilke: 7 articles (06/2014 - 10/2011)|
|3.||Fabbi, Marina: 7 articles (06/2013 - 04/2005)|
|4.||Ferrini, Silvano: 7 articles (06/2013 - 04/2005)|
|5.||Swart, Guido W M: 7 articles (05/2012 - 06/2002)|
|6.||Jänicke, Fritz: 6 articles (12/2014 - 02/2011)|
|7.||Sauter, Guido: 5 articles (12/2014 - 10/2011)|
|8.||Izbicki, Jakob R: 5 articles (06/2014 - 10/2011)|
|9.||Bockhorn, Maximilian: 5 articles (06/2014 - 10/2011)|
|10.||Gebauer, Florian: 5 articles (06/2014 - 10/2011)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "This study aimed to evaluate ALCAM as an early diagnostic biomarker for breast cancer and how it compares with other markers. "
12/01/2014 - "Loss of ALCAM expression is linked to adverse phenotype and poor prognosis in breast cancer: a TMA-based immunohistochemical study on 2,197 breast cancer patients."
04/01/2010 - "The present study investigated the biological influence of ALCAM on breast cancer cells in connection with bone biological environment. "
01/01/2004 - "The present study examined the expression of ALCAM in human breast cancer and assessed its prognostic value. "
01/01/2015 - "Tumour markers CEA, CA 15-3 and s ALCAM levels were determined and Group 2 consisted of breast cancer patients. "
05/01/2012 - "Our study suggests that overexpression of ALCAM contributes to tumor progression in MM and that ALCAM might be a potential therapeutic target of MM."
01/01/2012 - "Previous studies addressing ALCAM's role in cancer have, however, yielded conflicting results. "
01/01/2012 - "In this study, ALCAM expression was analysed by immunohistochemistry (IHC) in tissue samples of 233 patients with cervical cancer, among them 178 with complete follow-up information. "
05/01/2015 - "Differentially expressed/regulated cancer-related genes upon miR-125b expression along with the significant increase of ALCAM are of future interest to understand how deregulated expression of miR-125b may have a tumor suppressor role in breast and other cancers. "
05/01/2015 - "Given the tumor suppressor role of miR-125b in our model system, upon silencing of ALCAM expression, cell proliferation rate re-increased in miR-125b-expressing cells. "
|3.||Neoplasm Metastasis (Metastasis)
02/01/2008 - "The current study specifically investigated the ALCAM expression in tumours which developed skeletal metastasis. "
04/01/2014 - "These findings suggest that ALCAM/ALCAM and VLA-4/VCAM-1 interactions play an important functional role in the early stages of metastasis seeding in the brain. "
10/15/2013 - "CD45(-)ALCAM(+) cells induced bone metastasis de novo, but they also generated CD8(low) T cells with weak CTL activity in the periphery, which also promoted bone metastasis in an indirect manner. "
02/01/2013 - "The decreased ALCAM expression in TC correlated significantly with extrathyroidal extension, distant metastasis, and TC histotype. "
01/01/2013 - "Multivariate analysis revealed β-catenin membrane loss and ALCAM/β-catenin(nuclear/cytoplasmic) accumulation to be significant predictors for late clinical stage (p<0.001, OR = 8.7; p = 0.006, OR = 9.9, respectively) and nodal metastasis (p = 0.003, OR = 3.8; p = 0.025, OR = 3.4 respectively). "
|4.||Melanoma (Melanoma, Malignant)
01/01/2015 - "Our study is the first one to evaluate the effect of increased ALCAM expression on long-term survival in melanoma patients."
01/01/2015 - "The aim of the study was to assess the expression and intracellular localization of ALCAM in primary skin melanomas and metastatic lesions from regional lymph nodes. "
01/01/2015 - "The study using melanoma cell lines showed that overexpression of ALCAM is directly related with the increase of cytoaggregation and the ability to form cell nests. "
05/01/2012 - "In the present study, we analyzed differences in melanoma cell gene expression in two- and three-dimensional cultures as function of ALCAM-mediated adhesion. "
01/01/2015 - "Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients."
10/01/2014 - "Based on studies in which ALCAM showed prognostic relevance in several carcinomas, it has been discussed as a potential therapeutic target. "
10/15/1994 - "Among the cell lines tested, the human breast carcinoma-derived cell line HBL-100 expressed the highest levels of CD6 ligand(s) and was used for immunoprecipitation studies. "
01/01/2015 - "It could be concluded that serum ALCAM concentration represents a suitable biomarker for Saudi arabian breast carcinoma with high sensitivity and has the potential to be used as a diagnostic tool comparable to CA15-3 and CEA."
01/01/2012 - "The data of our retrospective study suggest that the prognostic value of ALCAM expression in cervical carcinoma might be therapy-dependent, and that ALCAM might function as a predictive marker for the response to chemoradiation. "
03/15/2008 - "Subcellular localization of activated leukocyte cell adhesion molecule is a molecular predictor of survival in ovarian carcinoma patients."
|1.||Activated-Leukocyte Cell Adhesion Molecule (Neurolin)
|2.||Matrix Metalloproteinase 2 (Gelatinase A)
|4.||Messenger RNA (mRNA)
|5.||Cell Adhesion Molecules
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)
|5.||Prostatectomy (Retropubic Prostatectomy)