RNA Helicases (RNA Helicase)

03/01/2022 - "This study revealed the role of RNA helicases in DNA damage and their associations with cancer, which could expand therapeutic strategies and improve precision treatments for cancer patients with high expression of RNA helicases. "
06/01/2019 - "Whole-exome sequencing studies identify recurrent somatic gene mutations, involving RNA helicases, tumor suppressors, JAK-STAT pathway molecules, and epigenetic modifiers. "
12/04/2018 - "Whole-exome sequencing studies identify recurrent somatic gene mutations, involving RNA helicases, tumor suppressors, JAK-STAT pathway molecules, and epigenetic modifiers. "
11/15/2023 - "RNA helicase DHX33 has been identified to be a critical factor in promoting cancer development. "
11/15/2023 - "Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents."

06/01/2012 - "   Genome-wide studies continue to identify helicase genes that change their expression patterns after infection or disease outbreak, but the mechanism of RNA helicase action has been defined for only a few diseases. "
05/09/2023 - "Here, we show that PRV infections hijack the RNA helicase DDX3X in sensory neurons to facilitate anterograde transport of the virus along axons. "
09/01/2020 - "DDX1 was the only DExD/H-box RNA helicase which expression was repetitively up-regulated during in vivo infections with SVCV and CSV in zebrafish and SVCV in common carp. "
01/01/2019 - "RNA helicases play an important role in the response to microbial infection. "
01/01/2019 - "Unraveling the role of the MOV10 RNA helicase during influenza A virus infection."

01/01/2022 - "RNA helicase DDX5 is downregulated during HBV replication and poor prognosis HBV-related hepatocellular carcinoma (HCC). "
01/01/2022 - "Here, we identified DHX37 as one of the top RNA helicase genes with upregulated expression in hepatocellular carcinoma (HCC). "
01/01/2022 - "RNA Helicase DDX24 Stabilizes LAMB1 to Promote Hepatocellular Carcinoma Progression."
01/01/2020 - "Rationale: RNA helicase DDX5 is downregulated during hepatitis B virus (HBV) replication, and poor prognosis HBV-related hepatocellular carcinoma (HCC). "
01/01/2020 - "Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma."

10/07/2021 - "(2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently induced for disease progression."
07/19/2013 - "We report here that hippuristanol (Hipp), a translation initiation inhibitor that selectively inhibits the eIF4F RNA helicase subunit, eIF4A, resensitizes Eμ-Myc lymphomas to DNA damaging agents, including those that overexpress eIF4E-a modifier of rapamycin responsiveness. "

10/07/2021 - "(2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently induced for disease progression."