|3.||Moyamoya Disease (Moya-Moya Disease)
|5.||Neurofibromatosis 1 (Neurofibromatosis Type I)
|1.||Gutmann, David H: 12 articles (10/2015 - 05/2007)|
|2.||Gianino, Scott M: 7 articles (06/2015 - 12/2008)|
|3.||Toonen, Joseph A: 3 articles (10/2015 - 05/2015)|
|4.||Riccardi, Riccardo: 3 articles (04/2015 - 05/2011)|
|5.||Falsini, Benedetto: 3 articles (04/2015 - 05/2011)|
|6.||Chiaretti, Antonio: 3 articles (04/2015 - 05/2011)|
|7.||Garbow, Joel R: 3 articles (07/2010 - 05/2007)|
|8.||Rubin, Joshua B: 3 articles (07/2010 - 09/2007)|
|9.||Daginakatte, Girish C: 3 articles (12/2008 - 05/2007)|
|10.||Pong, Winnie W: 2 articles (10/2015 - 01/2011)|
05/01/2015 - "In addition, all 3 Nf1 murine optic glioma strains exhibited reduced retinal ganglion cell survival and numbers; however, FMPC mice had greater retinal nerve fiber layer thinning near the optic head relative to FMC and FMBC mice. "
04/01/2015 - "To determine whether the Ganzfeld ERG photopic negative response (PhNR), an assay of inner retinal activity, is altered in childhood optic glioma (OPG). "
02/01/2011 - "We report a case of a 16-year-old girl with KTS who was found to have bilateral optic nerve and chiasmal gliomas, optic disk drusen, and acquired myelination of the retinal nerve fiber layer. "
07/01/2009 - "Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report."
11/01/2008 - "Retinal and optic nerve gliomas may be considered as differential diagnoses of intraocular and orbital masses. "
|3.||Mucin-1 (CA 15-3 Antigen)IBA
|4.||Reticulin (Reticular Fiber)IBA
|5.||Glial Fibrillary Acidic ProteinIBA
|6.||Sirolimus (Rapamycin)FDA Link
06/01/2015 - "Akt inhibition of Nf1-deficient astrocyte and optic glioma growth reflected Akt-dependent activation of mammalian target of rapamycin (mTOR). "
02/01/2011 - "Previous studies from our laboratory have shown that durable responses to rapamycin treatment in a genetically engineered mouse model of Nf1 optic glioma require 20 mg/kg/day, whereas only transient tumor growth suppression was observed with 5 mg/kg/day rapamycin despite complete silencing of ribosomal S6 activity. "
08/01/1991 - "Neoplastic astrocytes in optic nerve gliomas stained with GFAP, HNK-1, S-100, and vimentin. "
12/01/2007 - "The aim of the study was to investigate the relationship of serum levels of neuron-specific enolase, anti-vimentin IgG, and anti-vimentin IgM antibodies in patients with neurofibromatosis type 1 and associated tumors (optic glioma, and plexiform neurofibroma). "
|8.||Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
|9.||Phosphopyruvate Hydratase (Enolase)IBA
06/01/1985 - "In view of the substantial morbidity and mortality in reported series, and the tendency for referral of more serious cases to a radiotherapy center, we conclude from our results that radiotherapy is effective in preventing progression of optic glioma, and that treatment early in the course of the disease is indicated to minimize the associated visual deficit."
01/01/1987 - "Twenty-five children with optic gliomas were evaluated over a seven year period by sequential computed axial tomography in order to determine the efficacy of radiotherapy as a treatment modality. "
01/01/1987 - "Efficacy of radiotherapy in optic gliomas."
05/01/2013 - "In the current report, the authors present a case of optic nerve glioma treated with fractionated stereotactic radiotherapy (FSRT). "
05/01/2013 - "Optic nerve glioma treatment with fractionated stereotactic radiotherapy."
|2.||Drug Therapy (Chemotherapy)
01/01/2015 - "Her right eye was amblyopic because of an optic nerve glioma treated in childhood with chemotherapy. "
08/01/2014 - "Chemotherapy and radiation therapy can now stabilize and in some cases improve the vision of patients with optic nerve gliomas. "
03/01/2013 - "Three years earlier, she had undergone a limited biopsy, a course of chemotherapy, and orbital radiation therapy for a right optic nerve glioma with perineural arachnoidal gliomatosis (PAG). "
05/01/2012 - "A five-year-old boy received a clinical diagnosis of optic nerve glioma, and was followed-up for three months after chemotherapy. "
11/01/1992 - "This malignant optic nerve glioma followed the same aggressive clinical course as that seen in adults, with death 9 months after diagnosis despite surgery and chemotherapy. "
05/01/1985 - "Numerous clusters of benign choroid plexus epithelium were found in an ascitic fluid from a six-year-old girl with an optic nerve glioma and a ventriculoperitoneal shunt. "
08/15/1983 - "Metastatic spread of an optic glioma through a ventriculoperitoneal shunt resulted in the accumulation of malignant ascites in a young boy. "
08/15/1983 - "Metastasis of an optic glioma through a ventriculoperitoneal shunt."
03/01/2006 - "Her past medical history included a history of neurofibroma in the base of the brain, treated with radiation therapy and ventriculoperitoneal shunt, as well as a recent diagnosis of bilateral optic gliomas, treated with chemotherapy. "
01/01/1994 - "Although ascites following ventriculoperitoneal shunt placement is not typical in patients with optic gliomas, attention should be given to CSF protein levels documented at the time of CSF diversion for hydrocephalus, recognizing that ascites may occur as a result of poor CSF absorption in the periotoneum, subsequently requiring a ventriculoatrial shunt in patients who develop hydrocephalus."
09/01/1990 - "Twenty-one patients (13 boys, 8 girls), treated for optic glioma by cranial irradiation (45-55 Grays) at a mean age of 5.4 years, were evaluated before (n = 10) and/or after (n = 21) irradiation. "
12/20/2000 - "Calculation of normal tissue complication probabilities (NTCP) for proton radiation therapy (PRT) and two photon radiation therapy techniques for cranial irradiation of childhood optic nerve gliomas was made. "