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Spastic Paraparesis

Mild or moderate loss of motor function accompanied by spasticity in the lower extremities. This condition is a manifestation of CENTRAL NERVOUS SYSTEM DISEASES that cause injury to the motor cortex or descending motor pathways.
Also Known As:
Paraparesis, Spastic; Lower Extremity Weakness, Spastic; Spastic Lower Extremity Weakness; Parapareses, Spastic; Spastic Parapareses
Networked: 225 relevant articles (7 outcomes, 14 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neurologic Manifestations (Neurological Manifestations)
2. Multiple Sclerosis
3. Spinal Cord Ischemia
4. Ataxia (Dyssynergia)
5. Cataract (Cataracts)

Experts

1. Kakinohana, Manabu: 6 articles (03/2007 - 11/2002)
2. Sugahara, Kazuhiro: 5 articles (04/2006 - 11/2002)
3. Hardy, J: 5 articles (11/2001 - 03/2000)
4. Kalimo, H: 4 articles (07/2008 - 03/2000)
5. Verkkoniemi, A: 4 articles (07/2008 - 03/2000)
6. Nakamura, Seiya: 4 articles (04/2006 - 11/2002)
7. Abramsky, Oded: 3 articles (10/2015 - 02/2006)
8. Lossos, Alexander: 3 articles (10/2015 - 02/2006)
9. Paetau, A: 3 articles (07/2008 - 11/2000)
10. Crook, R: 3 articles (11/2001 - 03/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spastic Paraparesis:
1. Botulinum Toxins (Botulinum Toxin)IBA
2. BaclofenFDA LinkGeneric
3. Oligoclonal BandsIBA
4. Prednisolone (Predate)FDA LinkGeneric
5. Biotin (Vitamin H)FDA Link
6. Morphine (MS Contin)FDA LinkGeneric
7. Spastic paraplegia 17IBA
8. DNA (Deoxyribonucleic Acid)IBA
9. Type A Botulinum Toxins (Botulinum A Toxin)FDA Link
10. VitaminsIBA

Therapies and Procedures

1. Injections
2. Liver Transplantation
3. Rhizotomy
4. Decompression
5. Surgical Portasystemic Shunt (Portosystemic Shunt)