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Mobius Syndrome (Moebius Syndrome)

A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)
Also Known As:
Moebius Syndrome; Congenital Oculofacial Paralysis, Moebius; Congenital Ophthalmoplegia and Facial Paresis; Moebius Congenital Oculofacial Paralysis; Moebius Sequence; Moebius Spectrum; Möbius Sequence; Mobius Syndromes; Moebius Syndromes
Networked: 67 relevant articles (0 outcomes, 6 trials/studies)

Disease Context: Research Results

Related Diseases

1. Fetal Diseases (Embryopathy)
2. Goldenhar Syndrome (Hemifacial Microsomia)
3. CHARGE Syndrome
4. Benign Familial Pemphigus (Hailey Hailey Disease)
5. Retinitis Pigmentosa (Pigmentary Retinopathy)

Experts

1. Miller, Marilyn T: 5 articles (10/2014 - 06/2003)
2. Cardenas-Mejia, Alexander: 2 articles (11/2022 - 01/2020)
3. Telich-Tarriba, Jose E: 2 articles (11/2022 - 01/2020)
4. Dagi, Linda R: 2 articles (01/2022 - 10/2020)
5. Cassi, Diana: 2 articles (08/2018 - 01/2017)
6. Di Blasio, Alberto: 2 articles (08/2018 - 01/2017)
7. Gandolfini, Mauro: 2 articles (08/2018 - 01/2017)
8. Magnifico, Marisabel: 2 articles (08/2018 - 01/2017)
9. Brandt, Carlos Teixeira: 2 articles (10/2014 - 05/2012)
10. Goldchmit, Mauro: 2 articles (10/2014 - 05/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mobius Syndrome:
1. Misoprostol (Cytotec)FDA LinkGeneric
2. Thalidomide (Thalomid)FDA Link
3. Rhodopsin (Visual Purple)IBA
4. GoldIBA
5. Anesthetics (Anesthetic Agents)IBA
6. Semaphorins (Semaphorin)IBA
7. MicroRNAs (MicroRNA)IBA
8. KinesinsIBA
9. TubulinIBA
10. Antipsychotic Agents (Antipsychotics)IBA

Therapies and Procedures

1. Transplantation
2. Anesthesia
3. Airway Management
4. Tooth Extraction (Tooth Extractions)
5. Orthodontics