|1.||Ertl, Georg: 17 articles (03/2015 - 06/2002)|
|2.||Zornoff, Leonardo A M: 16 articles (01/2015 - 02/2005)|
|3.||Paiva, Sergio A R: 15 articles (01/2015 - 09/2005)|
|4.||Azevedo, Paula S: 14 articles (01/2015 - 09/2005)|
|5.||Minicucci, Marcos F: 14 articles (01/2015 - 09/2005)|
|6.||Bauersachs, Johann: 13 articles (11/2015 - 06/2002)|
|7.||Matsubara, Beatriz B: 13 articles (01/2013 - 09/2005)|
|8.||Matsubara, Luiz S: 12 articles (01/2011 - 09/2005)|
|9.||Janicki, Joseph S: 11 articles (01/2013 - 12/2002)|
|10.||Hayashi, Tetsuya: 10 articles (12/2014 - 06/2004)|
|1.||Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/01/2008 - "The HGF + G-CSF group exhibited improved left ventricular systolic and diastolic function and experienced less adverse ventricular remodeling, as manifested by decreased left ventricular dilatation and increased border zone wall thickness. "
10/01/2015 - "Our 3-year follow-up data from STEM-AMI trial documented a sustained benefit of G-CSF on adverse ventricular remodeling after large anterior STEMI, when administered early and at a high-dose in patients with left ventricular (LV) dysfunction. "
06/01/2011 - "The effect of granulocyte colony-stimulating factor (G-CSF) on post-infarct ventricular remodeling remains controversial. "
02/01/2006 - "The present study demonstrates that G-CSF mobilized autologous intracoronary PBSCs transplantation is a safe and feasible treatment for patients with AMI and global left ventricular function is improved and left ventricular remodeling attenuated at six-month follow-up."
11/07/2006 - "In conclusion, administration of G-CSF appears to be effective for treatment of left ventricular remodeling after acute myocardial infarction and does not aggravate vascular remodeling. "
|2.||Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/01/2002 - "Long-term adrenergic inhibition with the use of ss-adrenoceptor antagonists added to ACE inhibitors is associated with attenuation of ventricular remodeling, improvement in ventricular function and clinical class and survival of patients with symptomatic systolic left ventricular failure. "
12/01/2000 - "Further studies are necessary to assess if exercise training, associated with ACE-inhibitors and beta-blockers, can reverse or prevent left ventricular remodeling."
12/01/1993 - "However, studies comparing the effect of different doses of ACE inhibitors on left ventricular remodeling are missing. "
06/01/1993 - "At the time of publication, all available clinical trials studying the effects of ACE inhibitors on postinfarction ventricular remodeling were included, regardless of whether morbidity and mortality were assessed. "
10/01/1990 - "Recent experimental studies suggest a beneficial role of ACE inhibitors in attenuating reperfusion arrhythmias and postinfarction left ventricular remodeling. "
06/01/2013 - "Rats in the MI Ad-GFP-Sdc1 transfection group showed decreased ventricular weight, reduced collagen synthesis, and significant improvement of ventricular remodeling and cardiac function. "
09/01/2014 - "These results suggested that Rut ameliorates the right ventricular remodeling in rats with PH induced by MCT through down-regulating of NOX4 expression and collagen accumulation."
07/01/1996 - "The purpose of this study was to compare rates of infarct collagen deposition and ventricular remodeling in the two models. "
05/01/2015 - "The concentration of collagen degradation products (CDPs) may reflect the process of left ventricular remodeling (LVR). "
03/01/2014 - "During ventricular remodeling, as a result of iterations in the hemodynamic workload, collagen, the main component of the ECM, increases and occupies the areas between the myocytes and the vessels. "
12/01/2015 - "Aldosterone and Left Ventricular Remodeling."
05/22/2006 - "Our data demonstrate upregulation of MCR in the heart following MI what may facilitate the effects of aldosterone in the ventricular remodeling process. "
04/01/2000 - "Cardiac aldosterone production and ventricular remodeling."
08/01/1999 - "This activation is mediated by cardiac Ang II via AT1 receptor and the resultant increase of intracardiac aldosterone level may be involved in post-MI ventricular remodeling."
03/17/2011 - "The gender differences in aldosterone levels in patients with systemic right ventricles were similar to that associated with left ventricular remodeling in systemic arterial hypertension."
07/01/2005 - "Enalapril improved clinical status, left ventricular systolic function and affected favorably left ventricular remodeling. "
05/31/2011 - "We investigated the effect of polymorphisms in the renin-angiotensin-aldosterone system (RAAS) genes on ventricular remodeling, growth, renal function, and response to enalapril in infants with single ventricle. "
07/01/2005 - "Accupro compared with enalapril produces greater influence on left ventricular remodeling. "
08/01/1993 - "Those changes were suggestive of partial reversal of left ventricular remodeling by enalapril administration."
03/01/2002 - "To compare the effects of high, middle and low doses of enalapril in preventing left ventricular remodeling (LVRM) after acute myocardial infarction (AMI) in rats, especially evaluating the efficacy of low dose enalapril. "
|6.||Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
01/01/2002 - "A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' study."
12/01/1994 - "This study was designed to assess the effect of angiotensin-converting enzyme inhibition and beta-adrenoreceptor blockade on established ventricular remodeling. "
11/01/2005 - "beta-Blockers were added if echocardiography showed no ventricular remodeling in angiotensin-converting enzyme inhibitor-treated patients after 3 months. "
11/01/2004 - "Angiotensin-converting enzyme gene polymorphism, left ventricular remodeling, and exercise capacity in strength-trained athletes."
12/01/2000 - "Although angiotensin-converting enzyme inhibitor attenuates ventricular enlargement, whether beta-blocker therapy induces regression of left ventricular remodeling is not known. "
|7.||Biological Markers (Surrogate Marker)IBA
02/01/2011 - "Proteomic studies on HF biomarkers can be designed as case/control using clinical endpoints; alternatively, left ventricular remodeling can be used as a surrogate endpoint. "
12/01/2013 - "The ratio of left ventricular mass/left ventricular end diastolic volume was used as a surrogate marker of left ventricular remodeling. "
01/01/2013 - "DE occurrence is related to increased cardiac biomarkers, negative left ventricular remodeling and associated with a poor prognosis. "
01/01/2013 - "This approach shows the potential to select and identify candidate biomarkers in patients with left ventricular remodeling after MI."
03/01/2013 - "Investigations of these biomarkers have the potential to reveal early aspects of left ventricle remodeling; diagnosis at an earlier stage of heart failure promises to facilitate improved intervention and therapy guidance. "
01/01/2011 - "Protective effects of recombinant human erythropoietin against pressure overload-induced left ventricular remodeling and premature death in mice."
04/01/2006 - "Alteration in erythropoietin-induced cardioprotective signaling by postinfarct ventricular remodeling."
05/14/2004 - "Therefore, erythropoietin treatment may offer novel protection against ischemic heart disease and may act, at least in part, by direct action on cardiac fibroblasts and myocytes to alter survival and ventricular remodeling."
06/01/2010 - "Treatment of mice with erythropoietin inhibited left ventricular remodeling and improved cardiac function after myocardial infarction, independent of erythropoiesis and the mobilization of bone marrow-derived cells. "
11/01/2010 - "Design and rationale of the Reduction of Infarct Expansion and Ventricular Remodeling with Erythropoietin after Large Myocardial Infarction (REVEAL) trial."
|9.||Nitroglycerin (Dynamite)FDA LinkGeneric
02/27/1995 - "Preliminary evidence suggests that intravenous nitroglycerin may also be beneficial in preventing postinfarction ventricular remodeling, although it cannot yet be recommended for this purpose."
12/16/1993 - "Two subsequent clinical studies in the thrombolytic era, with low-dose intravenous nitroglycerin infusion during infarction over the first 48 hours followed by buccal nitrate (eccentric dose regimen) or placebo during healing over 6 weeks postinfarction, indicated that prolonged nitrate therapy effectively limited left ventricular remodeling and improved function further compared with placebo."
01/01/1991 - "Several trials are underway to test the effectiveness of more prolonged therapy, with early intravenous nitroglycerin followed by buccal or oral formulations for several weeks, in further limitation of ventricular remodeling, dilatation, aneurysm formation and in preserving function. "
03/15/1998 - "Design of a randomized, placebo-controlled multicenter trial on the long-term effects of intermittent transdermal nitroglycerin on left ventricular remodeling after acute myocardial infarction. "
06/01/1997 - "In conclusion, the early (within 72 hours) and prolonged (6 months) administration of transdermal nitroglycerin in acute myocardial infarction improves ejection fraction and stroke volume but does not modify ventricular remodeling."
04/01/2008 - "Ongoing studies evaluating the long-term renal protective effects of aliskiren and its effects on ventricular remodeling are currently planned or underway."
12/01/2012 - "NTX and MI resulted in deteriorated left ventricular remodeling and RAS activation, which was improved by an aliskiren that appeared to be independent of renal function and blood pressure (BP). "
09/01/2011 - "Moreover, aliskiren reduces markers of cardiac and renal disease, such as left ventricular hypertrophy or post-infarction ventricular remodeling, as well as proteinuria in diabetics already treated with other RAS blockers. "
01/01/2012 - "Combination therapy of valsartan and aliskiren more greatly improved ventricular remodeling after MI with enhancement of angiogenesis and greater attenuation of tissue oxidative stress and inflammation. "
01/01/2012 - "Aliskiren in combination with valsartan exerts synergistic protective effects against ventricular remodeling after myocardial infarction in mice."
|1.||Transplantation (Transplant Recipients)
03/01/2015 - "BMC transplantation is associated with a significant improvement in left ventricular ejection fraction and the attenuation of left ventricular remodeling."
09/11/2012 - "Transplantation significantly improved cardiac performance and attenuated left ventricular remodeling. "
12/05/2008 - "The present study aimed to investigate the effects of transplantation of autologous bone marrow mononuclear cells (BM-MNC) and mesenchymal stem cells (MSCs) via the coronary artery on the ventricle remodeling after AMI as well as the mechanisms of the effects of transplantation of different stem cells on ventricle remodeling. "
09/20/2006 - "This study aimed to evaluate the effects of human umbilical cord blood mononuclear cells (hUCBC) transplantation on cardiac function and left ventricular remodeling in rat model of MI. "
01/01/2016 - "Human myoblast transplantation in mice infarcted heart alters the expression profile of cardiac genes associated with left ventricle remodeling."
12/01/1999 - "Endocardial repair, ventricular remodeling, and selective myocardial revascularization provided overall good results in the treatment of this difficult cardiac area."
09/01/2014 - "The possibility of combining myocardial revascularization with surgical ventricular reconstruction (SVR) to reverse left ventricular remodeling or with mitral valve plasty to repair the incompetence of mitral valve coaptation has been examined in many trials, although little difference in the long-term outcomes between the simple revascularization and the combined procedure groups have been observed. "
04/01/2000 - "In our center we started to use this technique to analyze cardiac surgical procedures, like mitral valve reconstruction, aortic valve replacement, myocardial revascularization, left ventricular assist, and surgical left ventricular remodeling. "
08/01/1997 - "[Ventricular remodeling after myocardial revascularization with venous grafts]."
02/01/2004 - "In patients with ischemic cardiomyopathy not only the amount of dysfunctional but viable myocardium but also the extent of left ventricular remodeling determines the improvement in function following myocardial revascularization. "
|3.||Angioplasty (Angioplasty, Transluminal)
12/22/2014 - "The aim of the study was to assess the value of speckle tracking echocardiography in the prediction of left ventricular remodeling in patients after AMI and primary coronary angioplasty (PCI). "
05/01/2012 - "Prognostic value of reverse left ventricular remodeling after primary angioplasty for STEMI."
11/01/2011 - "Angiographic patterns of myocardial reperfusion after primary angioplasty and ventricular remodeling."
10/15/2006 - "Influence of transmurality, infarct size, and severe microvascular obstruction on left ventricular remodeling and function after primary coronary angioplasty."
04/01/2006 - "[Value of coronary blood flow pattern as a predictor of functional recovery and short-term left ventricular remodeling after primary coronary angioplasty. "
|4.||Stem Cell Transplantation
04/01/2011 - "Intracoronary stem cell transplantation could lead to improved ventricular remodeling, better exercise tolerance and potentially improved survival in patients with DCM."
07/01/2006 - "Considerable evidence from experimental studies and initial clinical trials suggests that stem cell transplantation promotes systolic function and prevent ventricular remodeling. "
09/01/2010 - "We analyse whether the assessment of myocardial viability may be important when evaluating effects of stem cell transplantation on parameters of left ventricular remodeling. "
11/20/2005 - "Early phase I clinical studies indicate that stem cell transplantation is feasible and may have beneficial effects on ventricular remodeling after myocardial infarction. "
05/04/2004 - "Early phase I clinical studies indicate that stem-cell transplantation is feasible and may have beneficial effects on ventricular remodeling after myocardial infarction. "
|5.||Cardiac Resynchronization Therapy
08/21/2002 - "Tissue Doppler imaging predicts improved systolic performance and reversed left ventricular remodeling during long-term cardiac resynchronization therapy."
04/27/2010 - "The purpose of this study was to describe the long-term course of left ventricular remodeling induced by cardiac resynchronization therapy (CRT), adjusting for the confounding effect of patient loss due to disease. "
03/01/2010 - "A number of trials have demonstrated the effect of cardiac resynchronization therapy (CRT) on functional improvement and reversed left ventricle remodeling. "
03/01/2015 - "The significance of reverse ventricular remodeling for long-term outcomes with cardiac resynchronization therapy."
03/01/2015 - "Reverse ventricular remodeling and long-term survival in patients undergoing cardiac resynchronization with surgically versus percutaneously placed left ventricular pacing leads."