Eastern Equine Encephalomyelitis

A form of arboviral encephalitis (primarily affecting equines) endemic to eastern regions of North America. The causative organism (ENCEPHALOMYELITIS VIRUS, EASTERN EQUINE) may be transmitted to humans via the bite of AEDES mosquitoes. Clinical manifestations include the acute onset of fever, HEADACHE, altered mentation, and SEIZURES followed by coma. The condition is fatal in up to 50% of cases. Recovery may be marked by residual neurologic deficits and EPILEPSY. (From Joynt, Clinical Neurology, 1996, Ch26, pp9-10)
Also Known As:
Encephalomyelitis, Eastern Equine; Eastern Equine Encephalitis; Eastern Equine Encephalitides; Eastern Equine Encephalomyelitides; Encephalitides, Eastern Equine; Encephalitis, Eastern Equine; Encephalomyelitides, Eastern Equine; Equine Encephalitides, Eastern; Equine Encephalitis, Eastern; Equine Encephalomyelitides, Eastern; Equine Encephalomyelitis, Eastern
Networked: 111 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. St. Louis Encephalitis
2. Infection
3. Venezuelan Equine Encephalomyelitis
4. Rabies (Hydrophobia)
5. Poliomyelitis (Polio)


1. Weaver, Scott C: 5 articles (12/2014 - 09/2005)
2. Wang, Eryu: 4 articles (12/2014 - 09/2005)
3. Parker, Michael D: 2 articles (10/2014 - 10/2002)
4. Reed, Douglas S: 2 articles (10/2014 - 06/2012)
5. Powers, Ann M: 2 articles (02/2014 - 01/2003)
6. Aguilar, Patricia V: 2 articles (10/2007 - 09/2005)
7. Paessler, Slobodan: 2 articles (10/2007 - 09/2005)
8. Wilkerson, M: 1 article (11/2015)
9. Davis, E G: 1 article (11/2015)
10. Bryan, A J: 1 article (11/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Eastern Equine Encephalomyelitis:
1. Poly I-CIBA
2. AntigensIBA
3. Chikungunya virus infectionIBA
06/01/2012 - "This review discusses the ecology, epidemiology and molecular virology of the alphaviruses, then focuses on three of the most important members of the genus: Venezuelan and eastern equine encephalitis and chikungunya viruses, with emphasis on their genetics and emergence mechanisms, and how current knowledge as well as gaps influence our ability to detect and determine the source of both natural outbreaks and potential use for bioterrorism. "
09/01/1992 - "There was also poor survival to the adult stage of Ae. taeniorhynchus inoculated with either eastern equine encephalomyelitis (EEE) or chikungunya (CHIK) virus. "
01/01/1975 - "The paper reports on serological results obtained by HAI tests against several alphaviruses - eastern equine encephalitis (EEE), western equine encephalitis (WEE), Chikungunya, Midlebourg, Semliki Forest, Sindbis, and Ilheus viruses - carried out in humans and some domestic animals in a region with an intensive circulation of migratory birds. "
03/01/2007 - "This study analyzes the risk of emergence of the alphaviruses Mayaro, Venezuelan equine encephalitis, Eastern equine encephalitis and Chikungunya; the flaviviruses yellow fever, Rocio, Saint Louis encephalitis and West Nile; and the orthobunyavirus Oropouche."
10/01/2010 - "Broad application of these assays is hindered by the lack of standardized positive human control sera that react with a wide variety of flaviviruses (e.g., dengue, West Nile, yellow fever, Japanese encephalitis, Saint Louis encephalitis, and Powassan viruses), or alphaviruses (e.g., Eastern equine encephalitis, Western equine encephalitis, Venezuelan equine encephalitis, and chikungunya viruses) that can cause human disease. "
4. Monoclonal AntibodiesIBA
5. Formaldehyde (Formol)FDA Link
6. EpitopesIBA
7. AntibodiesIBA
8. VaccinesIBA
9. Neutralizing AntibodiesIBA
10. Immunoglobulin M (IgM)IBA

Therapies and Procedures

1. Anesthesia
2. Injections
3. Immunotherapy