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Gait Ataxia

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Impairment of the ability to coordinate the movements required for normal ambulation (WALKING) which may result from impairments of motor function or sensory feedback. This condition may be associated with BRAIN DISEASES (including CEREBELLAR DISEASES and BASAL GANGLIA DISEASES); SPINAL CORD DISEASES; or PERIPHERAL NERVOUS SYSTEM DISEASES.

Also Known As:

Cerebellar Gait Ataxia; Gait Ataxia, Sensory; Ataxia, Cerebellar Gait; Ataxia, Gait; Ataxia, Sensory Gait; Ataxias, Cerebellar Gait; Ataxias, Gait; Ataxias, Sensory Gait; Cerebellar Gait Ataxias; Cerebellar Gaits; Gait Ataxia, Cerebellar; Gait Ataxias; Gait Ataxias, Cerebellar; Gait Ataxias, Sensory; Gait, Cerebellar; Gaits, Cerebellar; Sensory Gait Ataxia; Sensory Gait Ataxias; Ataxia of Gait; Cerebellar Gait

Networked: 37 relevant articles (3 outcomes, 1 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Dysarthria (Spastic Dysarthria)
2.	Seizures (Seizure)
3.	Essential Tremor (Essential Tremors)
4.	Ocular Motility Disorders (Convergence Insufficiency)
5.	Vomiting

Experts

1.	Wenzelburger, R: 2 articles (07/2005 - 09/2002)
2.	Stolze, H: 2 articles (07/2005 - 09/2002)
3.	Klebe, S: 2 articles (07/2005 - 09/2002)
4.	Deuschl, G: 2 articles (07/2005 - 09/2002)
5.	Tomsak, Robert L: 1 article (09/2009)
6.	Thurtell, Matthew J: 1 article (09/2009)
7.	Newman, Nancy J: 1 article (09/2009)
8.	Leigh, R John: 1 article (09/2009)
9.	Fraser, J Alexander: 1 article (09/2009)
10.	Biousse, Valérie: 1 article (09/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Gait Ataxia:

1.	Piracetam (Nootropil)IBA 04/01/2008 - "CONCLUSION: This study is providing good clinical observation in favour of high dose piracetam infusion to reduce the disability of the patients by improving their gait ataxia." 11/01/1996 - "Piracetam also had positive benefits on gait ataxia and convulsions but not on dysarthria, and feeding and hand writing improved much more significantly. " 04/01/2003 - "Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g. " Order ALL the reference details at left...
2.	Ethanol (Ethyl Alcohol)IBA 07/12/2005 - "CONCLUSIONS: Orally administered ethanol improved gait ataxia in patients with essential tremor (ET). " Order ALL the reference details at left...
3.	TANDEMIBA 09/01/2009 - "One patient had obvious extremity and gait ataxia, but the other had only an unsteady tandem gait. " 09/01/2002 - "The tandem gait paradigm accentuates all the features of gait ataxia and is the most sensitive clinical test." 09/01/2002 - "A tandem gait paradigm was used to quantify gait ataxia. " 04/01/2003 - "Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g. " Order ALL the reference details at left...
4.	Pyridoxine (Pyridoxin)FDA Link 11/01/1985 - "When rats received pyridoxine in doses large enough to cause neuropathy in humans, the animals developed gait ataxia that subsided after the toxin was withdrawn. " 06/01/1990 - "In another group pyridoxine (vitamin B6) neuropathy was induced which is a purely sensory neuropathy clinically presenting with gait ataxia, too. " Order ALL the reference details at left...
5.	alpha-Fetoproteins (AFP)IBA 04/01/2004 - "Ataxia with oculomotor apraxia type 2 (AOA2) is a newly described autosomal recessive cerebellar ataxia (ARCA) defined by genetic location to 9q34 of three families sharing gait ataxia, oculomotor apraxia and/or elevated alpha-foetoprotein (AFP) levels. " 01/01/2009 - "BACKGROUND: The autosomal recessively inherited ataxia with oculomotor apraxia 2 (AOA2) is a neurodegenerative disorder characterized by juvenile or adolescent age of onset, gait ataxia, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor apraxia, and elevated serum AFP levels. " Order ALL the reference details at left...
6.	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 09/01/2003 - "GDNF and IGF-I trophic factors delay hereditary Purkinje cell degeneration and the progression of gait ataxia." Order ALL the reference details at left...
7.	Vitamin B 6IBA 06/01/1990 - "In another group pyridoxine (vitamin B6) neuropathy was induced which is a purely sensory neuropathy clinically presenting with gait ataxia, too. " Order ALL the reference details at left...
8.	Myelin-Associated Glycoprotein (S-MAG)IBA 08/01/2005 - "This review focuses on the actual status and recent advances in the treatment of immune-mediated neuropathies, including: Guillain-Barre syndrome (GBS) with its subtypes acute inflammatory demyelinating polyradiculoneuropathy, acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, Miller Fisher syndrome, and acute pandysautonomia; chronic inflammatory demyelinating polyneuropathy (CIDP) with its subtypes classical CIDP, CIDP with diabetes, CIDP/monoclonal gammopathy of undetermined significance (MGUS), sensory CIDP, multifocal motor neuropathy (MMN), multifocal acquired demyelinating sensory and motor neuropathy or Lewis-Sumner syndrome, multifocal acquired sensory and motor neuropathy, and distal acquired demyelinating sensory neuropathy; IgM monoclonal gammopathies with its subtypes Waldenstrom's macroglobulinemia, myelin-associated glycoprotein-associated gammopathy, polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome, mixed cryoglobulinemia, gait ataxia, late-onset polyneuropathy syndrome, and MGUS. " Order ALL the reference details at left...
9.	Tacrolimus (Prograf)FDA LinkGeneric 04/01/2005 - "This 49-year-old woman developed progressive gait ataxia and right-sided hemiparesis after 7 years of tacrolimus therapy for focal sclerosing glomerulonephritis. " Order ALL the reference details at left...
10.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 02/01/1995 - "Those particularly associated with valproate were weight increase, alopecia and appetite increase, and with carbamazepine, rashes, somnolence, diplopia and abnormal gait/ataxia." Order ALL the reference details at left...

Therapies and Procedures

1.	Aftercare (After-Treatment) 06/01/2002 - "Prominent improvement in gait ataxia occurred after treatment with human immune globulin but not after other immunomodulating therapies. " Order ALL the reference details at left...
2.	Surgical Decompression 01/01/2008 - "The patient presented with initial symptoms of airway difficulties and gait ataxia, which did not progress clinically over this period of observation, despite recommendations for surgical decompression. " Order ALL the reference details at left...
3.	Cranial Irradiation 07/01/1987 - "Six patients with small cell lung cancer developed a slowly progressive neurologic syndrome characterized by apathy, abulia, memory loss, gait ataxia, and corticospinal tract signs 26 to 50 months (mean, 35.2 months) after prophylactic cranial irradiation and systemic chemotherapy. " Order ALL the reference details at left...
4.	Liver Transplantation 12/01/2007 - "These findings suggest that some of the purported "sequelae" of liver transplantation (gait ataxia, memory loss, confusion) could reflect preexisting neuropathology." Order ALL the reference details at left...
5.	Transplantation (Transplant Recipients) 07/31/1998 - "Ten years after the dural transplantation, the patient developed gait ataxia, paresthesia of both legs, myoclonus and visual disturbance. " Order ALL the reference details at left...

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