Facial Nerve Injuries

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76 relevant articles (4 outcomes, 6 trials/studies) found for this Disease

Description: Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., "crocodile tears") and other syndromes.

Also Known As:

Cranial Nerve VII Injuries; Facial Nerve Avulsion; Injuries, Cranial Nerve VII; Injuries, Seventh Cranial Nerve; Injury, Facial Nerve; Nerve Injury, Facial; Seventh Cranial Nerve Injuries; Avulsion, Facial Nerve; Avulsions, Facial Nerve; Facial Nerve Avulsions; Facial Nerve Injury; Facial Nerve Traumas; Facial Neuropathies, Traumatic; Injuries, Facial Nerve; Nerve Avulsion, Facial; Nerve Avulsions, Facial; Nerve Injuries, Facial; Nerve Trauma, Facial; Nerve Traumas, Facial; Neuropathies, Traumatic Facial; Neuropathy, Traumatic Facial; Trauma, Facial Nerve; Traumas, Facial Nerve; Traumatic Facial Neuropathies; Traumatic Facial Neuropathy; Facial Nerve Trauma; Facial Neuropathy, Traumatic

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3406

Cranial Nerve Diseases: 147

Facial Nerve Diseases: 36

Facial Nerve Injuries: 76

Cranial Nerve Injuries: 34

Facial Nerve Injuries: 76

Nervous System Trauma: 41

Craniocerebral Trauma: 3289

Cranial Nerve Injuries: 34

Facial Nerve Injuries: 76

Disorders of Environmental Origin

Wounds and Injuries: 60616

Craniocerebral Trauma: 3289

Cranial Nerve Injuries: 34

Facial Nerve Injuries: 76

Nervous System Trauma: 41

Craniocerebral Trauma: 3289

Cranial Nerve Injuries: 34

Facial Nerve Injuries: 76

Related Diseases

1.	Cicatrix
2.	Ankylosis
3.	Hematoma
4.	Neoplasms (Cancer)
5.	Paralysis (Palsy)
29 Diseases and 26 more articles analyzed in the Research Interface, order at left...

Experts

1.	Watabe, Kazuhiko: 3 articles (10/2005 - 04/2003)
2.	Sakamoto, Tsuyoshi: 3 articles (10/2005 - 04/2003)
3.	Kawazoe, Yoko: 3 articles (10/2005 - 04/2003)
4.	Wurster, Robert D: 2 articles (07/2008 - 07/2002)
5.	Ikeda, Ken: 2 articles (10/2005 - 06/2003)
6.	Tanzer, Lisa: 1 article (07/2008)
7.	Leonetti, John: 1 article (07/2008)
8.	Foecking, Eileen M: 1 article (07/2008)
9.	Marzo, Sam J: 1 article (07/2008)
10.	Hetzler, Laura E T: 1 article (07/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Facial Nerve Injuries:

1.	CosmeticsIBA 11/01/2006 - "The main advantages of this procedure are that the small operative scar is concealed in the submental skin crease, resulting in improved cosmetic results and minimization of the possibility of facial nerve injury." 05/01/2008 - "Paralysis of the orbicularis oculi muscle in patients with a facial nerve injury causes functional and cosmetic disabilities including inability to close the eyelid" 04/01/2007 - "However, when the lesions are limited to the face only, surgical scar and facial nerve injury may impair cosmetics and facial expression" 08/01/2001 - "At a 39-month follow-up, the patient had achieved an excellent cosmetic and functional result, with no alopecia or facial nerve injury" 06/01/2000 - "We recommend the transantral anterior approach for relatively small, benign lesions that show no evidence of invasion into surrounding tissues because it does not expose the patient to surgical complications such as transient or permanent facial nerve injury or cosmetic deformity." Get all the results and reference details, order at left...
2.	T 588IBA 06/01/2003 - "CONCLUSION: These results indicate that oral administration of T-588 ameliorates the survival of injured motoneurons and supports their neuronal function after facial nerve avulsion in adult rats" 06/01/2003 - "We investigated whether orally administered T-588 can rescue injured motoneurons after facial nerve avulsion in adult rats" 06/01/2003 - "Oral administration of a neuroprotective compound T-588 prevents motoneuron degeneration after facial nerve avulsion in adult rats." Get all the results and reference details, order at left...
3.	Flavin Mononucleotide (FMN)IBA 06/05/1999 - "ER were neither present nor induced with facial nerve injury or TP administration in either the FMN or Nu5" 01/01/2000 - "In this study, to clarify the pathologic change in the FMN after axotomy and to determine the best time for surgery, facial motoneuronal death was investigated after facial nerve injury" 06/05/1999 - "The recent discovery of transient estrogen receptor (ER) expression in the developing rat facial motor nucleus (FMN), coupled with the concept that regeneration may recapitulate development, has led to the hypothesis that facial nerve injury may transiently induce expression of ER in the adult hamster FMN or one of its chief afferents, the principal nucleus of the trigeminal nerve (Nu5)" 11/06/1995 - "Two days after facial nerve avulsion, increased NADPH-d activity was noticed in the facial motoneurons and in the endothelial lining of many dilated blood vessels in the facial motor nucleus (FMN)" 12/01/2000 - "Testosterone propionate (TP) administration at the time of facial nerve injury in the adult hamster augments the regenerative properties of the injured facial motoneurons (FMN), with the androgen receptor (AR) playing a key role in mediating the actions of TP on facial nerve regeneration" Get all the results and reference details, order at left...
4.	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 07/01/2006 - "In the present study, we investigated whether astrocyte-derived GDNF could also have a neuroprotective effect on adult MNs following facial nerve avulsion" 06/26/2000 - "After facial nerve avulsion, animals locally injected into the facial canal with AxCALacZ (adenovirus encoding beta-galactosidase gene) or AxCAhGDNF showed expression of beta-galactosidase activity or intense immunolabeling for GDNF in lesioned facial motoneurons, respectively" 04/01/2003 - "Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion." Get all the results and reference details, order at left...
5.	Nitric Oxide Synthase (NO Synthase)IBA 11/06/1995 - "The present study aimed to determine whether nitric oxide synthase (NOS)/nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity would be induced in facial motoneurons after facial nerve avulsion and if so, whether such activity was related to neuronal death commonly observed after such injury" Get all the results and reference details, order at left...
6.	NADPH Dehydrogenase (Dehydrogenase, NADP)IBA 11/06/1995 - "The present study aimed to determine whether nitric oxide synthase (NOS)/nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity would be induced in facial motoneurons after facial nerve avulsion and if so, whether such activity was related to neuronal death commonly observed after such injury" Get all the results and reference details, order at left...
7.	NADP (NADPH)IBA 11/06/1995 - "Two days after facial nerve avulsion, increased NADPH-d activity was noticed in the facial motoneurons and in the endothelial lining of many dilated blood vessels in the facial motor nucleus (FMN)" 11/06/1995 - "The present study aimed to determine whether nitric oxide synthase (NOS)/nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) activity would be induced in facial motoneurons after facial nerve avulsion and if so, whether such activity was related to neuronal death commonly observed after such injury" Get all the results and reference details, order at left...
8.	Testosterone Propionate FDA Link 11/01/1997 - "Testosterone propionate (TP) administered at the time of facial nerve injury in the hamster accelerates the rate of regeneration" 04/01/1997 - "In recent work, we have demonstrated that testosterone propionate accelerates recovery from facial nerve injury in the adult male hamster" 05/01/2004 - "We have previously demonstrated that testosterone propionate (TP) administered systemically at supraphysiological levels accelerates both recovery from facial paralysis and regeneration rates following facial nerve injury in the hamster" 06/01/2002 - "Testosterone propionate (TP) administration coincident with facial nerve injury accelerates the recovery rate from facial muscle paralysis in the hamster" 12/01/2000 - "Testosterone propionate (TP) administration at the time of facial nerve injury in the adult hamster augments the regenerative properties of the injured facial motoneurons (FMN), with the androgen receptor (AR) playing a key role in mediating the actions of TP on facial nerve regeneration" Get all the results and reference details, order at left...
9.	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 01/02/2008 - "PACAP-deficient mice were used here to investigate actions of endogenous PACAP after facial nerve injury" 12/15/2004 - "These data indicated that PACAP promotes the regeneration factors and increases the possibility of functional recovery following the facial nerve injury." 12/15/2004 - "PACAP facilitate the nerve regeneration factors in the facial nerve injury." Get all the results and reference details, order at left...
10.	Ciliary Neurotrophic Factor (CNTF)IBA 04/01/2008 - "An analysis of time-dependent changes of neurotrophic factors (BDNF, CNTF) in traumatic facial nerve injury of a nerve-cut and nerve-crush model in rats." 04/01/2003 - "Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion." Get all the results and reference details, order at left...
42 Drugs and Important Bio-Agents and 43 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	X-Ray Film 04/01/1976 - "Prior to surgery, the assessment of taste and hearing, as well as mastoid and skull