Central Cord Syndrome

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18 relevant articles (0 outcomes, 1 trials/studies) found for this Disease

Description: A syndrome associated with traumatic injury to the cervical or upper thoracic regions of the spinal cord characterized by weakness in the arms with relative sparing of the legs and variable sensory loss. This condition is associated with ischemia, hemorrhage, or necrosis involving the central portions of the spinal cord. Corticospinal fibers destined for the legs are spared due to their more external location in the spinal cord. This clinical pattern may emerge during recovery from spinal shock. Deficits may be transient or permanent.

Also Known As:

Central Cord Injury Syndrome; Central Spinal Cord Syndrome

Disease Context: Research Results

Nervous System Diseases: 3414

Central Nervous System Diseases: 930

Spinal Cord Diseases: 1312

Spinal Cord Injuries: 4702

Central Cord Syndrome: 18

Nervous System Trauma: 41

Spinal Cord Injuries: 4702

Central Cord Syndrome: 18

Disorders of Environmental Origin

Wounds and Injuries: 60713

Spinal Cord Injuries: 4702

Central Cord Syndrome: 18

Related Diseases

1.	Syringomyelia (Morvan's Disease)
2.	Aspiration Pneumonia
3.	Airway Obstruction (Choking)
4.	Brown-Sequard Syndrome (Syndrome, Brown-Sequard)
5.	Bacteremia

Experts

1.	Dickerman, Rob D: 1 article (10/2005)
2.	Lefkowitz, Michael: 1 article (10/2005)
3.	Epstein, Joseph A: 1 article (10/2005)
4.	Levi, Allan D: 1 article (06/2005)
5.	Vanni, Steven: 1 article (06/2005)
6.	Guest, James D: 1 article (06/2005)
7.	Moza, Kapil: 1 article (06/2005)
8.	Green, Barth A: 1 article (06/2005)
9.	Uribe, Juan: 1 article (06/2005)
10.	Suk, Kyung-Soo: 1 article (02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Central Cord Syndrome:

1.	Methicillin (Metin)FDA Link 01/01/2007 - "The patient presented with acute central cord syndrome and lower-extremity paraplegia after completing a 6-week course of intravenous antibiotics for methicillin-sensitive Staphylococcus aureus bacteremia and osteomyelitis of the thoracic spine" Order ALL the reference details at left...
2.	Diazepam (Valium)FDA LinkGeneric 05/01/1977 - "Based on the experience to date with central cord syndrome, most or all of the following conditions should be present before considering transurethral sphincterotomy: (1) minimal neurological recovery within 6 months of injury; (2) four plus spasticity in patients over the age of 50 years; (3) prolonged intermittent catheterisation over 6 months, with persistent residual urine over 300 ml; (4) persistent and repeated use of diazepam, dantrolene sodium to control pelvic floor spasticity; (5) demonstrable detrusor-sphincter dyssynergia." Order ALL the reference details at left...
3.	Dantrolene (Dantrium)FDA LinkGeneric 05/01/1977 - "Based on the experience to date with central cord syndrome, most or all of the following conditions should be present before considering transurethral sphincterotomy: (1) minimal neurological recovery within 6 months of injury; (2) four plus spasticity in patients over the age of 50 years; (3) prolonged intermittent catheterisation over 6 months, with persistent residual urine over 300 ml; (4) persistent and repeated use of diazepam, dantrolene sodium to control pelvic floor spasticity; (5) demonstrable detrusor-sphincter dyssynergia." Order ALL the reference details at left...
4.	Carbon MonoxideIBA 10/01/2001 - "We report a case of an elderly man presenting with co-existing diffuse idiopathic skeletal hyperostosis (DISH) and ossified posterior longitudinal ligament (OPLL) resulting in central cord syndrome" Order ALL the reference details at left...
5.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2007 - "The patient presented with acute central cord syndrome and lower-extremity paraplegia after completing a 6-week course of intravenous antibiotics for methicillin-sensitive Staphylococcus aureus bacteremia and osteomyelitis of the thoracic spine" Order ALL the reference details at left...
6.	gabapentin (Neurontin)FDA LinkGeneric 09/01/2003 - "This report describes a case where central cord syndrome and its chronic neuropathic pain associated with allodynia was successfully treated with gabapentin." Order ALL the reference details at left...
7.	A 7 (A-7)IBA 03/01/1996 - "We report a case of a central cord syndrome in a 7 year-old girl" Order ALL the reference details at left...

Therapies and Procedures

1.	Surgical Decompression 06/01/2005 - "Acute traumatic central cord syndrome--experience using surgical decompression with open-door expansile cervical laminoplasty." 11/01/1999 - "Our study shows that 1) surgical decompression was indicated in all patients with brain stem and lower cranial nerve dysfunction as well as central cord syndrome caused by syringomyelia; 2) a better result was achieved in those patients who received adequate nervous system decompression; and 3) much attention should be payed to cases with lower cranial nerves XI, X, XII impairment, because complications such as choking and aspiration pneumonia can happen." Order ALL the reference details at left...
2.	Decompression 10/15/2005 - "The patient fell in the rehabilitation center, with a central cord syndrome despite adequate decompression of her spinal canal" 10/15/2005 - "To our knowledge, there are no cases of a central cord syndrome occurring after adequate decompression reported in the literature" 10/15/2005 - "A traumatic central cord syndrome occurring after adequate decompression for cervical spondylosis: biomechanics of injury: case report." 10/15/2005 - "OBJECTIVES: To present the first case of a central cord syndrome occurring after adequate decompression, and review the mechanics of the cervical spinal cord injury and postoperative biomechanical and anatomic changes occurring after cervical decompressive laminectomy" 11/01/1999 - "Our study shows that 1) surgical decompression was indicated in all patients with brain stem and lower cranial nerve dysfunction as well as central cord syndrome caused by syringomyelia; 2) a better result was achieved in those patients who received adequate nervous system decompression; and 3) much attention should be payed to cases with lower cranial nerves XI, X, XII impairment, because complications such as choking and aspiration pneumonia can happen." Order ALL the reference details at left...
3.	Laminectomy 08/01/1995 - "The significance of dorsal migration of the cord after extensive cervical laminectomy for patients with traumatic central cord syndrome." 10/01/1982 - "We report five cases of a central cord syndrome that appeared as a delayed surgical complication several days after decompressive laminectomy with the patient in the sitting position" 10/01/1982 - "Central cord syndrome as a delayed postoperative complication of decompressive laminectomy." 10/15/2005 - "OBJECTIVES: To present the first case of a central cord syndrome occurring after adequate decompression, and review the mechanics of the cervical spinal cord injury and postoperative biomechanical and anatomic changes occurring after cervical decompressive laminectomy" Order ALL the reference details at left...
4.	Orthotic Devices (Orthosis) 10/01/1998 - "This report describes a unique orthosis designed to assist activities of daily living for a patient with severe proximal upper limb weakness caused by traumatic central cord syndrome" 11/01/1990 - "A new orthosis for central cord syndrome and brachial plexus injuries." Order ALL the reference details at left...
5.	Anesthesia 01/01/2007 - "Upon waking up from anesthesia, one patient in the monitored group had a new neurological deficit (partial central cord syndrome) despite normal intraoperative SSEP signals" 02/15/2005 - "OBJECTIVE: To present a patient with central cord syndrome injury after total hip arthroplasty performed under general endotracheal anesthesia" Order ALL the reference details at left...

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