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Nervous System Trauma

Traumatic injuries to the brain, cranial nerves, spinal cord, autonomic nervous system, or neuromuscular system, including iatrogenic injuries induced by surgical procedures.
Also Known As:
Trauma, Nervous System; Axonotmesis; Injuries, Nervous System; Neurotmesis; Axonotmeses; Craniocervical Injury; Nervous System Injury; Nervous System Traumas; Neurotmeses; Craniocervical Injuries; Nervous System Injuries
Networked: 291 relevant articles (17 outcomes, 42 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Nervous System Trauma
2. Wounds and Injuries (Trauma)
3. Mandibular Fractures
4. Spinal Cord Injuries (Spinal Cord Injury)
5. False Aneurysm (Pseudoaneurysm)

Experts

1. Geuna, Stefano: 7 articles (11/2022 - 01/2010)
2. Maurício, Ana Colette: 6 articles (11/2022 - 10/2012)
3. Raimondo, Stefania: 6 articles (11/2022 - 01/2010)
4. Amado, Sandra: 6 articles (01/2021 - 01/2010)
5. Schachner, Melitta: 6 articles (01/2019 - 01/2012)
6. Pires, Isabel: 5 articles (11/2022 - 07/2015)
7. Prada, Justina: 5 articles (11/2022 - 07/2015)
8. Luís, Ana Lúcia: 5 articles (02/2020 - 10/2012)
9. Luís, Ana L: 4 articles (11/2022 - 01/2010)
10. Shen, Jun: 4 articles (01/2020 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Nervous System Trauma:
1. ChitosanIBA
2. Nerve Growth Factors (Neurotrophins)IBA
05/01/2015 - "The strong repair and pro-survival functions of neurotrophins at their primary receptors, TrkA, TrkB and TrkC, have made them attractive candidates for treatment of nervous system injury and disease. "
07/01/2012 - "While neurotrophic factors have been shown to stimulate axonal growth in numerous animal models of nervous system injury, a lack of suitable growth substrates, an insufficient activation of neuron-intrinsic regenerative programs, and extracellular inhibitors of regeneration limit the efficacy of neurotrophic factor delivery for anatomical and functional recovery after spinal cord injury. "
10/01/2002 - "Changing the levels of neurotrophins in the spinal cord micro-environment after nervous system injury has been proposed to recover normal function, such that behavioral response to peripheral stimuli does not lead to chronic pain. "
01/01/2021 - "Locally, the PMP dissociation brought by drugs contributed to the reversion of the pathological condition: the focus of the cellular function shift from survival after nervous system injury into development and repair, including neurotrophin regulation, hormone releasing, and chemokine signaling activation. "
11/01/2012 - "The purpose of this study was to evaluate the mRNA expression of neurotrophic factors (brain-derived neurotrophic factor [BDNF], nerve growth factor [NGF], and neurotrophin-3, [NT-3]) and also an inflammatory marker (induced nitric oxide synthase [iNOS]) in an axonotmesis experimental model after low-level laser therapy. "
3. Biocompatible Materials (Biomaterials)IBA
4. Peptides (Polypeptides)IBA
5. Dexamethasone (Maxidex)FDA LinkGeneric
6. HydrogelsIBA
7. Tacrolimus (Prograf)FDA LinkGeneric
8. Peroxisome Proliferator-Activated Receptors (PPAR)IBA
9. Peroxisome ProliferatorsIBA
10. Serotonin ReceptorsIBA

Therapies and Procedures

1. Surgical Amputation (Amputations)
2. Transplantation
3. Low-Level Light Therapy (LLLT)
4. Lasers (Laser)
5. Brain-Computer Interfaces