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Pinacidil (Pindac)

A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Also Known As:
Pindac; Pinacidil Anhydrous; Anhydrous, Pinacidil; Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropylmonohydrate), (+-)-
Networked: 260 relevant articles (20 outcomes, 38 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Cao, Su: 3 articles (07/2015 - 05/2015)
2. Shen, Shiren: 3 articles (07/2015 - 05/2015)
3. Franova, S: 3 articles (01/2015 - 11/2007)
4. Sutovska, M: 3 articles (01/2015 - 11/2007)
5. Tkachenko, H M: 3 articles (01/2004 - 09/2003)
6. Kurhaliuk, N M: 3 articles (01/2004 - 09/2003)
7. Miki, T: 3 articles (12/2003 - 03/2001)
8. Chen, Junjie: 2 articles (07/2015 - 05/2015)
9. Kaya, Salih Tunç: 2 articles (02/2015 - 10/2013)
10. Jaggar, Jonathan H: 2 articles (08/2014 - 10/2011)

Related Diseases

1. Ischemia
2. Hypertension (High Blood Pressure)
3. Reperfusion Injury
4. Anoxia (Hypoxia)
5. Ventricular Fibrillation

Related Drugs and Biologics

1. Adenosine Triphosphate (ATP)
2. Potassium Channels (Potassium Channel)
3. Cromakalim (Levcromakalim)
4. KATP Channels
5. Potassium
6. Glyburide (Glibenclamide)
7. Thomas' solution
8. Calcium
9. Adenosine
10. Adenosine A1 Receptor

Related Therapies and Procedures

1. Induced Heart Arrest (Cardioplegia)
2. Ligation
3. Warm Ischemia
4. Injections
5. Intravenous Infusions