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Milrinone (Primacor)

A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
Also Known As:
Primacor; Corotrop; Corotrope; Milrinone Lactate; Win-47203; Lactate, Milrinone; Win 47203; Win47203; (3,4'-Bipyridine)-5-carbonitrile, 6-dihydro-2-methyl-6-oxo-
Networked: 867 relevant articles (131 outcomes, 152 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Denault, André Y: 10 articles (01/2020 - 05/2006)
2. Gheorghiade, Mihai: 10 articles (05/2008 - 03/2002)
3. McNamara, Patrick J: 8 articles (01/2021 - 06/2006)
4. O'Connor, Christopher M: 7 articles (05/2008 - 03/2002)
5. Cheung, Po-Yin: 6 articles (01/2018 - 07/2008)
6. Wang, Shih-Min: 6 articles (01/2016 - 03/2005)
7. Califf, Robert M: 6 articles (05/2008 - 03/2002)
8. Leimberger, Jeffrey D: 6 articles (05/2008 - 01/2003)
9. Felker, G Michael: 6 articles (12/2006 - 01/2003)
10. Teitelbaum, Jeanne: 5 articles (04/2022 - 06/2012)

Related Diseases

1. Heart Failure
2. Pulmonary Hypertension
3. Low Cardiac Output
4. Intracranial Vasospasm
5. Cardiogenic Shock

Related Drugs and Biologics

1. Dobutamine
2. Amrinone (Amrinon)
3. Vasodilator Agents (Vasodilators)
4. Type 3 Cyclic Nucleotide Phosphodiesterases
5. Phosphodiesterase Inhibitors
6. Simendan (Levosimendan)
7. Phosphoric Diester Hydrolases (Phosphodiesterases)
8. Sildenafil Citrate (Viagra)
9. Catecholamines
10. zaprinast

Related Therapies and Procedures

1. Therapeutics
2. Cardiopulmonary Bypass (Heart-Lung Bypass)
3. Intravenous Infusions
4. Heart Transplantation (Grafting, Heart)
5. Ligation