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Immunophilins

Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.
Also Known As:
Neurophilin; Neurophilins
Networked: 37 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ratajczak, Thomas: 2 articles (05/2015 - 01/2015)
2. Yoon, Ho Sup: 2 articles (01/2015 - 01/2008)
3. Lagadari, Mariana: 2 articles (04/2013 - 07/2012)
4. Galigniana, Mario D: 2 articles (04/2013 - 07/2012)
5. Erlejman, Alejandra G: 2 articles (04/2013 - 07/2012)
6. Redondo, P C: 2 articles (01/2013 - 01/2011)
7. Rosado, J A: 2 articles (01/2013 - 01/2011)
8. Achim, Cristian L: 2 articles (08/2009 - 06/2009)
9. Everall, Ian P: 2 articles (08/2009 - 06/2009)
10. Tatro, Erick T: 2 articles (08/2009 - 06/2009)

Related Diseases

1. Spinal Cord Injuries (Spinal Cord Injury)
2. Infection
3. Ischemia
4. Breast Neoplasms (Breast Cancer)
5. Chronic Hepatitis C

Related Drugs and Biologics

1. FK1706
2. Tacrolimus Binding Proteins (FKBP)
3. tacrolimus binding protein 4 (FKBP52)
4. Tacrolimus Binding Protein 1A (FKBP12)
5. Cyclophilins (Cyclophilin)
6. Peptidylprolyl Isomerase (Prolyl Isomerase)
7. Molecular Probes (Molecular Probe)
8. Messenger RNA (mRNA)
9. Ligands
10. Tacrolimus (Prograf)