|1.||Ratajczak, Thomas: 2 articles (05/2015 - 01/2015)|
|2.||Yoon, Ho Sup: 2 articles (01/2015 - 01/2008)|
|3.||Lagadari, Mariana: 2 articles (04/2013 - 07/2012)|
|4.||Galigniana, Mario D: 2 articles (04/2013 - 07/2012)|
|5.||Erlejman, Alejandra G: 2 articles (04/2013 - 07/2012)|
|6.||Redondo, P C: 2 articles (01/2013 - 01/2011)|
|7.||Rosado, J A: 2 articles (01/2013 - 01/2011)|
|8.||Achim, Cristian L: 2 articles (08/2009 - 06/2009)|
|9.||Everall, Ian P: 2 articles (08/2009 - 06/2009)|
|10.||Tatro, Erick T: 2 articles (08/2009 - 06/2009)|
|1.||Spinal Cord Injuries (Spinal Cord Injury)
09/04/2008 - "FK1706, a novel non-immunosuppressant neurophilin ligand, ameliorates motor dysfunction following spinal cord injury through its neuroregenerative action."
09/04/2008 - "FK1706, a non-immunosuppressant neurophilin ligand, potentiates nerve growth factor signaling, suggesting therapeutic potential for functional deficits following spinal cord injury. "
01/01/2008 - "These immunophilin ligands show variable efficacy in animal models for Parkinson's disease, dementia, and spinal cord injury, where the canonical immunophilins function as chaperones and are associate with the protein folding and modulation of oxidative stress. "
10/01/2015 - "This review summarizes emerging research that defines the functions of immunophilins in supporting the replication cycles of HIV-1, HCV, HBV, coronaviruses, and other viral pathogens and describes new information that suggests a role for immunophilins in regulating innate immune responses against chronic viral infection. "
10/01/2015 - "The role of immunophilins in viral infection."
08/01/2006 - "It is possible that HIV-1 infection of murine cells is inhibited by dominant factors related to immunophilins."
08/01/2002 - "We investigated whether immunophilins affect HIV-1 infection by assuming they are able to bind to the V3 loop of gp120. "
08/01/2002 - "Immunophilins and HIV-1 infection."
12/25/2009 - "The findings indicate important mechanisms related to these immunophilins in the reaction to ischemia/hypoxia and reperfusion in the heart."
12/25/2009 - "The primary aim of this study was to evaluate protein release into the myocardium in a porcine model during ischemia and reperfusion to search for clarifying models for reperfusion injury and secondarily to investigate release and production of the immunophilins FKBP12/12.6 in this model and in cell cultures. "
04/01/2002 - "CsA, FK506 and other derivatives inhibit the function of immunophilins and, through bloking or activating several intracellular pathways, it has been shown that they exert neuroprotective effects in different experimental models of ischemia, Parkinson's disease and excitotoxic insults. "
|4.||Breast Neoplasms (Breast Cancer)
12/01/1999 - "Since previous studies have not assessed the levels of these immunophilins in breast cancer, we examined 10 breast cancer cell lines for mRNA and protein expression of CyP40 and FKBP52 and for amplification of the CyP40 gene. "
12/01/1999 - "Both immunophilins were also ubiquitously expressed in breast carcinomas, and we demonstrate for the first time that both CyP40 and FKBP52 mRNA are overexpressed in breast tumors compared to matched normal breast controls. "
06/01/2001 - "Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells."
12/01/1999 - "Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer."
|5.||Chronic Hepatitis C
10/01/2015 - "Peptidyl-prolyl isomerase inhibitors have been used in clinical trials to validate cyclophilins as antiviral targets for the treatment of HIV-1 and Chronic Hepatitis C virus infection and as molecular probes to identify the roles played by immunophilins in supporting the replication cycles of human viruses. "
|2.||Tacrolimus Binding Proteins (FKBP)
|3.||tacrolimus binding protein 4 (FKBP52)
|4.||Tacrolimus Binding Protein 1A (FKBP12)
|6.||Peptidylprolyl Isomerase (Prolyl Isomerase)
|7.||Molecular Probes (Molecular Probe)
|8.||Messenger RNA (mRNA)