Silicone Gels

Synthetic organosiloxane gels that are formed from synthetic polymers of silicone oxide with organic sidechains (polydimethylsiloxane) by lengthening the polymer chains. Unlike silicone elastomers, they are not treated with amorphous silica. They are used as fillers in breast implants.

Also Known As:

Networked: 27 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hoeksema, Henk: 3 articles (05/2022 - 11/2013)
2.	Monstrey, Stan: 3 articles (05/2022 - 11/2013)
3.	Verbelen, Jozef: 3 articles (05/2022 - 11/2013)
4.	Blondeel, Phillip: 2 articles (05/2022 - 04/2022)
5.	Claes, Karel E Y: 2 articles (05/2022 - 04/2022)
6.	De Coninck, Petra: 2 articles (05/2022 - 04/2022)
7.	De Decker, Ignace: 2 articles (05/2022 - 04/2022)
8.	Speeckaert, Marijn M: 2 articles (05/2022 - 04/2022)
9.	Vanlerberghe, Els: 2 articles (05/2022 - 04/2022)
10.	Beeckman, Anse: 1 article (04/2022)

Related Diseases

1.	Cicatrix (Scar) 12/01/2021 - "Recently, studies have shown improvement in scar appearance after treating with silicone gels containing natural herbal ingredients. " 01/01/2023 - "To mitigate the potential long-term consequences of scarring and the impact of scarring on their everyday lives, children may be expected to use a variety of time-consuming and multi-component non-invasive scar treatments (such as pressure garments and silicone gels). " 01/01/2023 - "Based on excellent clinical results after using three specific moisturizers for scar treatment in our patients, we wanted to investigate whether these moisturizers induce comparable occlusion and hydration compared to both each other and the widely recognized liquid silicone gels. " 01/01/2023 - "Occlusion and hydration of scars: moisturizers versus silicone gels." 12/01/2019 - "The entire scar was also treated with standard moisturizers and silicone gels. "
2.	Hypertrophic Cicatrix (Hypertrophic Scar) 01/01/2022 - "The use of fluid silicone gels in the prevention and treatment of hypertrophic scars: a systematic review and meta-analysis." 07/01/2012 - "These results suggest the possible use of the PEG-PDMS-PEG block co-oligomers as an alternative to silicone gels for hypertrophic scar remediation." 01/01/2022 - "Studies on the effects of liquid silicone gels on hypertrophic scars are numerous and this systematic review shows that the use of liquid silicone gels is associated with both a prophylactic and a curative effect on scars. " 08/01/2019 - "Silicone gels have only been used to treat keloids and hypertrophic scars and typically applied after the wound has healed. " 05/01/2015 - "The objective of this review was to systematically evaluate available clinical evidence for the application of nonsilicone or silicone gels and gel sheets on hypertrophic scars and keloids after a burn injury so that practice guidelines could be proposed. "
3.	Neoplasms (Cancer) 04/01/2012 - "In the present study, the ability of laypeople to detect artificial tumors of various hardness values embedded in silicone gels was assessed in a simulated MIS environment. "
4.	Plasmacytoma 02/01/1998 - "We postulate that this mutagenicity may be a critical determinant of the plasmacytoma inducing potency of silicone gels. " 02/01/1998 - "Small fragments of silicone gels injected intraperitoneally have been used to induce plasmacytomas in genetically susceptible mice. " 01/01/1996 - "Silicone gels are well tolerated for long periods of time in mice without adverse effects other than plasmacytoma formation. " 01/01/1996 - "Silicone gels derived from commercially obtained implants induce plasmacytomas in 60-70% of highly susceptible BALB/cAn.DBA/2-Idh1-Pep3 congenic mice. " 01/01/1996 - "Plasmacytoma development in mice injected with silicone gels."
5.	Wounds and Injuries (Trauma) 09/15/2005 - "One hundred wounds in 50 patients were randomized into two arms, 50 control and 50 silicone gels. " 08/01/2019 - "Silicone gels have only been used to treat keloids and hypertrophic scars and typically applied after the wound has healed. " 06/01/1994 - "Wound management can be changed to meet changing wound needs, with dressings as diverse as hydrocolloids, silicone gels, and amino acids. "

Related Drugs and Biologics

1.	Silicones
2.	Type A Botulinum Toxins (Botox)
3.	Verapamil (Calan)
4.	Triamcinolone Acetonide (Azmacort)
5.	Fluorouracil (Carac)
6.	Bleomycin (Blenoxane)
7.	Oils
8.	Complex Mixtures
9.	Collagen Type II (Type II Collagen)
10.	Triamcinolone (Aristocort)

Related Therapies and Procedures

1.	Cryotherapy (Therapy, Cold)
2.	Breast Implants (Breast Implant)
3.	Therapeutics
4.	Radiotherapy
5.	Lasers (Laser)