|1.||Levitzki, Alexander: 5 articles (01/2006 - 09/2002)|
|2.||Klein, Andrzej: 3 articles (01/2012 - 01/2008)|
|3.||Bojko, Agnieszka: 2 articles (01/2015 - 01/2012)|
|4.||Ligeza, Janusz: 2 articles (01/2015 - 01/2008)|
|5.||Adamczyk, Anna: 2 articles (01/2015 - 01/2012)|
|6.||Ligęza, Janusz: 2 articles (01/2012 - 01/2011)|
|7.||Ligęza, Joanna: 2 articles (01/2012 - 01/2011)|
|8.||Di Paola, Rosanna: 2 articles (06/2007 - 11/2005)|
|9.||Cuzzocrea, Salvatore: 2 articles (06/2007 - 11/2005)|
|10.||Genovese, Tiziana: 2 articles (06/2007 - 11/2005)|
|1.||Septic Shock (Toxic Shock Syndrome)
04/15/1997 - "Using a canine model of gram-negative septic shock, we investigated the effect of tyrosine kinase inhibitors (tyrphostins) on survival. "
06/01/2004 - "Tyrphostins AG-126 and AG-556 were previously shown to reduce TNF-alpha production and its end-organ cytotoxicity, thus proving beneficial in animal models of septic shock and experimental autoimmune encephalomyelitis. "
09/01/1997 - "6 Thus, tyrphostins (AG126, AG556, AG1641 or A1) and genistein, but not daidzein (inactive analogue of genistein), prevent the (i) circulatory failure, (ii) the multiple organ dysfunction (liver and pancreatic dysfunction/injury lactacidosis, hypoglycaemia), as well as (iii) the induction of iNOS and COX-2 protein and activity in rats with endotoxic shock."
|2.||Murine Acquired Immunodeficiency Syndrome (MAIDS)
12/05/2000 - "These results implicate that prolonged treatment with tyrphostins is needed for the prevention of MAIDS development in infected mice and suggest that it may be applied as a legitimate remedy for the treatment of retroviral-induced diseases."
12/05/2000 - "Furthermore, weekly treatment with tyrphostins totally abolished MAIDS symptoms and prevented the viral infection of the spleen cells as measured by the absence of viral RNA and the restoration of T-cell function in these spleens. "
|3.||Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/01/2001 - "Effect of tyrphostins on programmed cell death in colon adenocarcinoma cell line LS-180."
01/01/2001 - "We investigated the influence of tyrphostins, that specifically inhibits protein tyrosine kinases and stops the cell cycle in apoptosis of the colon adenocarcinoma cell line LS180. "
08/01/1994 - "The ability of the 32 tyrphostins synthesized in the present study to inhibit proliferation of a human breast adenocarcinoma cell line (MCF-7) was determined using [3H]thymidine incorporation as a measure of DNA synthesis. "
|5.||Acute Kidney Injury (Acute Renal Failure)
01/01/2010 - "We review the potential role of tyrphostins in the prophylaxis and treatment of acute kidney injury on the basis of published studies on animals, in vitro experiments and piecemeal information from humans. "
01/01/2010 - "Tyrphostins as potential therapeutic agents for acute kidney injury."
|1.||AG 127 (AG 126)
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|4.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|6.||DNA (Deoxyribonucleic Acid)
|7.||tyrphostin AG 1478
|10.||Messenger RNA (mRNA)
|1.||Estrogen Replacement Therapy