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Activated Protein C Resistance (APC Resistance)

A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
Also Known As:
APC Resistance; Resistance, APC
Networked: 1122 relevant articles (14 outcomes, 97 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Venous Thromboembolism
2. Thrombosis (Thrombus)
3. Venous Thrombosis (Deep-Vein Thrombosis)
4. Thrombophilia
5. Protein S Deficiency (Deficiency, Protein S)

Experts

1. Rosing, Jan: 27 articles (08/2014 - 03/2002)
2. Rosing, J: 22 articles (11/2014 - 07/2000)
3. Tans, Guido: 13 articles (09/2006 - 03/2002)
4. Castoldi, Elisabetta: 12 articles (08/2014 - 09/2002)
5. Van Cott, Elizabeth M: 10 articles (12/2014 - 05/2002)
6. Dahlbäck, Björn: 10 articles (01/2008 - 05/2002)
7. Favaloro, Emmanuel J: 9 articles (09/2012 - 08/2002)
8. Tans, G: 9 articles (02/2009 - 07/2000)
9. Rosendaal, F R: 8 articles (04/2014 - 05/2000)
10. Simioni, Paolo: 7 articles (08/2014 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Activated Protein C Resistance:
1. factor V LeidenIBA
2. Factor V (Coagulation Factor V)IBA
3. Prothrombin (Factor II)IBA
4. Protein CIBA
5. Protein SIBA
6. DNA (Deoxyribonucleic Acid)IBA
7. ThrombinFDA Link
8. Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA
9. AnticoagulantsIBA
10. A-factor (Streptomyces)IBA

Therapies and Procedures

1. Hormone Replacement Therapy (Therapy, Hormone Replacement)
2. Transplants (Transplant)
3. Intrauterine Devices (Intrauterine Device)
4. Liver Transplantation
5. Transplantation (Transplant Recipients)