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Cyclin-Dependent Kinase Inhibitor p16

A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.
Also Known As:
CDKN2 Protein; CDKN2A Protein; Cdk4-Associated Protein p16; Cyclin-Dependent Kinase Inhibitor-2A; INK4A Protein; MTS1 Protein; Multiple Tumor Suppressor-1; p16(INK4A); p16INK4 Protein; p16INK4A Protein; Cdk4 Associated Protein p16; Cyclin Dependent Kinase Inhibitor 2A; Cyclin Dependent Kinase Inhibitor p16; Multiple Tumor Suppressor 1; Protein, INK4A
Networked: 1558 relevant articles (30 outcomes, 206 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Sharpless, Norman E: 21 articles (04/2014 - 05/2002)
2. von Knebel Doeberitz, Magnus: 17 articles (06/2015 - 11/2002)
3. Reuschenbach, Miriam: 11 articles (06/2015 - 01/2012)
4. DePinho, Ronald A: 11 articles (09/2007 - 01/2002)
5. Aboussekhra, Abdelilah: 9 articles (10/2015 - 01/2004)
6. Hara, Eiji: 8 articles (01/2015 - 09/2005)
7. Nakanuma, Yasuni: 8 articles (03/2014 - 07/2008)
8. Sasaki, Motoko: 8 articles (03/2014 - 07/2008)
9. Liu, Yan: 8 articles (10/2012 - 01/2009)
10. Herman, James G: 7 articles (06/2010 - 08/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Squamous Cell Carcinoma (Epidermoid Carcinoma)
3. Adenocarcinoma
4. Glioblastoma (Glioblastoma Multiforme)
5. Lung Neoplasms (Lung Cancer)

Related Drugs and Biologics

1. Biological Markers (Surrogate Marker)
2. DNA (Deoxyribonucleic Acid)
3. Messenger RNA (mRNA)
4. Antibodies
5. beta Catenin
6. Carrier Proteins (Binding Protein)
7. RNA (Ribonucleic Acid)
8. Keratins (Keratin)
9. trichostatin A (A 300)
10. Acetic Acid (Vinegar)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Aftercare (After-Treatment)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Prostatectomy (Retropubic Prostatectomy)