Cyclin E

01/01/2006 - "Cyclin E expression was inversely correlated with tumor grade therefore may be helpful in establishing therapeutic procedure."
01/01/2019 - "This study demonstrated that high cyclin E and HGF expression is closely correlated with tumor size, tumor differentiation degree, and TNM stage in patients with ESCC. "
12/08/2015 - "Overall, the study indicates that MAGE-C2 is involved in SCF complex and increases the stability of cyclin E in tumor cells. "
04/30/2015 - "Our study showed that ectopic expression of Oct4 promotes tumor growth through cyclin E activation, increases chemoresistance through ABCC6 expression and enhances tumor invasion through slug expression. "
09/01/2014 - "In this study, we showed that higher doses of I3C (≥400 μM) induced apoptotic cancer cell death and lower doses of I3C (≤200 μM) repressed cancer cell growth concurrently with suppressed expression of cyclin E and its partner CDK2. "

05/18/2015 - "Analysis of a large set of breast tumors shows a significant correlation between cyclin E amplification and deletions at a number of the genomic loci identified in our study. "
12/01/2013 - "We conducted a final analysis of 7,759 patients from 23 eligible studies and evaluated the correlation between cyclin E overexpression and survival in patients with breast cancer. "
12/01/2013 - "A meta-analysis was conducted with eligible studies which quantitatively evaluated the relationship between cyclin E overexpression and survival of patients with breast cancer. "
12/01/2013 - "Various studies examined the relationship between cyclin E overexpression with the clinical outcome in patients with breast cancer but yielded conflicting results. "
07/01/2011 - "In this study, levels of full-form/LMWI cyclin E were determined with the use of Western blot analysis in 69 Japanese breast cancer patients. "

03/01/2008 - "The expression of cyclin E is independent prognostic factor in rectal carcinoma at stages I- III. Detecting the expression of cyclin E and/or combined with BVI may help to predict clinical outcome and design further individualized intensive adjuvant treatment."
04/10/2006 - "We set out to study the expression of cyclin E over the cell cycle in cervical carcinomas. "
01/01/2017 - "Other molecular changes in serous carcinoma detectable by immunohistochemistry involve cyclin E and p16. "
11/01/2016 - "We also demonstrated the percentage of MCM4 and MCM7 expression to be significantly correlated with Ki-67, Bmi1, and cyclin E expression in esophageal carcinoma and precancerous lesions. "
08/02/2016 - "ARTD1 regulates cyclin E expression and consequently cell-cycle re-entry and G1/S progression in T24 bladder carcinoma cells."

01/01/2018 - "Does cyclin E and p57kıp2 expression have prognostic and survival value in colorectal adenocarcinoma?"
04/17/2014 - "Importantly, cyclin E is also amplified and highly expressed in a subset of esophageal adenocarcinoma patients, but this increase is not associated with worse prognosis."
04/17/2014 - "However, the level changes of cyclin E in esophageal adenocarcinoma and its precancerous lesion have not been well studied. "
05/01/2009 - "Does the expression of cyclin E, pRb, and p21 correlate with prognosis in gastric adenocarcinoma?"
08/01/2007 - "LMW cyclin E overexpression in mammary epithelial cells of mice is sufficient by itself to induce mammary adenocarcinomas in 34 of 124 (27%) animals compared with 7 of 67 (10.4%) mice expressing only the full-length cyclin E (P < 0.05). "

01/01/2018 - "Immunohistochemical expressions of cyclin E and p57KIP2 in 80 pairs of colorectal carcinoma and adjacent normal mucosal tissues were evaluated and the findings were compared with clinicopathological parameters and survival time. "
01/01/2013 - "In conclusion, our data suggest that overexpression of cyclin E does not predict the clinical outcome in colorectal cancer stage III. Negative cyclin E staining may be associated with lymph node involvement."
01/01/2013 - "The clinical significance of the expression of cyclin E in stage III colorectal carcinoma has not yet been investigated. "
01/01/2013 - "Expression of cyclin E in stage III colorectal carcinoma."
02/10/2012 - "Activation of Akt induces expression of c-Myc and cyclin E, which are overexpressed in colorectal cancer and play an important role in colorectal cancer cell proliferation. "