|1.||Jans, David A: 5 articles (12/2013 - 09/2002)|
|2.||El-Sayed, Mostafa A: 3 articles (03/2014 - 09/2007)|
|3.||Reilly, Raymond M: 3 articles (11/2013 - 08/2012)|
|4.||Samant, Rajeev S: 2 articles (12/2015 - 06/2012)|
|5.||Chen, Yi-Wei: 2 articles (01/2015 - 05/2012)|
|6.||Huang, Pin-I: 2 articles (01/2015 - 05/2012)|
|7.||Lo, Wen-Liang: 2 articles (01/2015 - 05/2012)|
|8.||Tseng, Ling-Ming: 2 articles (01/2015 - 05/2012)|
|9.||Chang, Yuh-Lih: 2 articles (01/2015 - 05/2012)|
|10.||Basse, Per H: 2 articles (08/2014 - 05/2011)|
09/15/2014 - "We observed frequent somatic alterations in BRCA1 associated protein-1 (BAP1) in 15% of tumors, including deleterious alterations to the deubiquitinase active site and the nuclear localization signal. "
10/01/2012 - "Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1."
05/13/2011 - "A naturally occurring, tumor-derived mutant LT (MCV350) lacking a nuclear localization signal binds hVam6p but fails to inhibit hVam6p-induced lysosomal clustering. "
01/01/2011 - "The tumor suppressive activity of nuclear DLC1 was directly assessed by employing a nuclear localization signal (NLS) fusion variant of DLC1 (NLS-DLC1) with preferential nuclear localization. "
12/01/2010 - "We detected a novel missense mutation in the nuclear localization signal coding region of the LKB1 gene in 10 tumor samples from patients with HNC. "
|2.||Testicular Neoplasms (Testicular Cancer)
03/01/2006 - "Together, these studies map critical residues of the Vpx nuclear localization signal that are required for efficient infection of non-dividing cells."
08/01/2015 - "We also found that residues (20)KY(21) constitute a nuclear localization signal that is not required for the ability of MxB to block HIV-1 infection."
01/01/2013 - "These observations have demonstrated that the hypothetical protein CT311 possesses a novel nuclear localization signal sequence with dual modules of basic residues for targeting host cell nucleus during Chlamydia trachomatis infection."
09/01/2012 - "A Nuclear localization signal in herpesvirus protein VP1-2 is essential for infection via capsid routing to the nuclear pore."
10/01/2009 - "The nuclear localization signal of the NS1 protein is essential for Periplaneta fuliginosa densovirus infection."
|4.||Breast Neoplasms (Breast Cancer)
08/25/2013 - "The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs)."
07/01/2009 - "A biomimetic vector was genetically engineered to contain at precise locations (a) an adenovirus mu peptide to condense pDNA into nanosize particles, (b) a synthetic cyclic peptide to target breast cancer cells and enhance internalization of nanoparticles, (c) a pH-responsive synthetic fusogenic peptide to disrupt endosome membranes and facilitate escape of the nanoparticles into the cytosol, and (d) a nuclear localization signal from human immunodeficiency virus for microtubule mediated transfer of genetic material to the nucleus. "
04/01/2003 - "Further support for 80K-H nuclearization was provided by the immunostaining of human breast cancer specimens and computer-assisted identification of a putative nuclear localization signal (NLS) near the amino terminus of 80K-H protein structure. "
12/01/2015 - "One of its isoforms, DNAJB6a, contains a nuclear localization signal and regulates β-catenin signaling during breast cancer development. "
07/01/2013 - "Primary structure analysis of the protein revealed a Pescadillo N-terminus domain, a single breast cancer C-terminal domain, two nuclear localization signals, and a potential coiled-coil region as also found in animal PESCADILLO proteins. "
|5.||Prion Diseases (Transmissible Spongiform Encephalopathies)
05/01/2013 - "The prion protein (PrP)-known for its central role in transmissible spongiform encephalopathies-has been reported to possess two nuclear localization signals and localize in the nuclei of certain cells in various forms. "
04/10/2001 - "Anti-huntingtin sFv fused with a nuclear localization signal retargeted huntingtin analogues to cell nuclei, providing further evidence of the anti-huntingtin sFv specificity and of its capacity to redirect the subcellular localization of exon 1. This study suggests that intrabody-mediated modulation of abnormal neuronal proteins may contribute to the treatment of neurodegenerative diseases such as HD, Alzheimer's, Parkinson's, prion disease, and the spinocerebellar ataxias."
|3.||Heat-Shock Proteins (Heat-Shock Protein)
|4.||Proteins (Proteins, Gene)
|8.||Tumor Viral Antigens (Large T Antigen)
|9.||DNA (Deoxyribonucleic Acid)
|10.||Nuclear Export Signals (Nuclear Export Signal)
|3.||Heterologous Transplantation (Xenotransplantation)