HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Phosphatidylinositol 3-Kinases

Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
Also Known As:
PI 3-Kinase; PI-3K; PI3 Kinases; PI3-Kinase; Phosphoinositide 3-Hydroxykinase; PtdIns 3-Kinases; 3-Kinases, PtdIns; Kinases, PI3; Phosphatidylinositol 3 Kinases; PtdIns 3 Kinases; PI-3 Kinase; Phosphatidylinositol-3-OH Kinase; PtdIns 3-Kinase
Networked: 715 relevant articles (12 outcomes, 59 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Draznin, Boris: 8 articles (03/2009 - 01/2002)
2. Durden, Donald L: 5 articles (09/2014 - 01/2010)
3. Asano, Tomoichiro: 4 articles (07/2014 - 12/2002)
4. Ye, Keqiang: 4 articles (03/2010 - 12/2004)
5. Leitner, J Wayne: 4 articles (03/2009 - 08/2004)
6. Klippel, Anke: 4 articles (06/2006 - 06/2002)
7. Sasaoka, T: 4 articles (02/2005 - 08/2001)
8. Vanhaesebroeck, Bart: 3 articles (12/2014 - 04/2013)
9. Katagiri, Hideki: 3 articles (07/2014 - 12/2002)
10. Ono, Hiraku: 3 articles (07/2014 - 12/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Ischemia
3. Reperfusion Injury
4. Insulin Resistance
5. Infection

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Protein Kinases (Protein Kinase)
3. Proto-Oncogene Proteins c-akt (Protein Kinase B)
4. Insulin (Novolin)
5. Phosphatidylinositols (Phosphatidylinositol)
6. DNA (Deoxyribonucleic Acid)
7. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
8. lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)
9. DNA-Activated Protein Kinase
10. Serine (L-Serine)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Ischemic Postconditioning
4. Chemoprevention
5. Therapeutics