HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome)

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
Also Known As:
Goodpasture's Syndrome; Goodpasture Syndrome; Anti GBM Disease; Syndrome, Goodpasture's; Lung Purpura with Nephritis; Anti Glomerular Basement Membrane Disease; Goodpastures Syndrome; Syndrome, Goodpasture; Anti-GBM Disease
Networked: 663 relevant articles (21 outcomes, 43 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Glomerulonephritis
2. Systemic Lupus Erythematosus (Libman-Sacks Disease)
3. Hemorrhage
4. Myasthenia Gravis
5. Vasculitis (Vasculitides)

Experts

1. Cui, Zhao: 26 articles (07/2015 - 10/2004)
2. Zhao, Ming-Hui: 15 articles (01/2014 - 07/2005)
3. Zhao, Ming-hui: 13 articles (07/2015 - 10/2004)
4. Yang, Rui: 12 articles (01/2014 - 08/2007)
5. Hellmark, Thomas: 10 articles (02/2014 - 01/2003)
6. Zhao, Juan: 9 articles (09/2011 - 06/2009)
7. Borza, Dorin-Bogdan: 8 articles (10/2015 - 10/2003)
8. Jia, Xiao-yu: 8 articles (07/2015 - 11/2009)
9. Pusey, Charles D: 6 articles (06/2015 - 02/2004)
10. Segelmark, Mårten: 6 articles (02/2014 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anti-Glomerular Basement Membrane Disease:
1. antiglomerular basement membrane antibodyIBA
2. Cyclophosphamide (Cytoxan)FDA LinkGeneric
3. AntibodiesIBA
4. Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
5. SteroidsIBA
6. Immunoglobulin G (IgG)IBA
7. Idiopathic pulmonary hemosiderosisIBA
8. Antigen-Antibody Complex (Immune Complex)IBA
9. Immunoglobulin A (IgA)IBA
10. alemtuzumab (Campath)FDA Link

Therapies and Procedures

1. Plasmapheresis
2. Plasma Exchange
3. Blood Component Removal (Apheresis)
4. Transplants (Transplant)
5. Tissue Therapy (Cell Therapy)