|2.||Systemic Lupus Erythematosus (Libman-Sacks Disease)
|1.||Cui, Zhao: 26 articles (07/2015 - 10/2004)|
|2.||Zhao, Ming-Hui: 15 articles (01/2014 - 07/2005)|
|3.||Zhao, Ming-hui: 13 articles (07/2015 - 10/2004)|
|4.||Yang, Rui: 12 articles (01/2014 - 08/2007)|
|5.||Hellmark, Thomas: 10 articles (02/2014 - 01/2003)|
|6.||Zhao, Juan: 9 articles (09/2011 - 06/2009)|
|7.||Borza, Dorin-Bogdan: 8 articles (10/2015 - 10/2003)|
|8.||Jia, Xiao-yu: 8 articles (07/2015 - 11/2009)|
|9.||Pusey, Charles D: 6 articles (06/2015 - 02/2004)|
|10.||Segelmark, Mårten: 6 articles (02/2014 - 01/2003)|
|1.||antiglomerular basement membrane antibodyIBA
04/01/1988 - "This case illustrates that life-threatening relapse may occur in Goodpasture's syndrome despite a prolonged remission and the disappearance of detectable antiglomerular basement membrane antibody in the circulation."
05/01/2006 - "In this study, we investigated the effect of IA on serum anti-GBM level and evaluated its clinical efficacy in patients with Goodpasture's syndrome. "
08/01/1998 - "Thus, this study underscores cytokine and adhesion molecule requirements for neutrophil mediated injury in lung and kidney caused by anti-GBM, suggesting potential targets for the treatment of Goodpasture's syndrome in humans."
07/01/1995 - "As with recent studies in human anti-GBM disease, there was no evidence for affinity maturation of the anti-GBM response in the serum of any of the animal models. "
01/01/2015 - "Anti-GBM antibody assays were reported as slightly raised; thus, the diagnosis was anti-GBM disease with normal renal function. "
|2.||Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/15/1982 - "[Goodpasture's syndrome--rapid remission after early plasmapheresis and high-dose cyclophosphamide therapy (author's transl)]."
08/01/1999 - "These findings suggest that cyclophosphamide pulse therapy is effective against Goodpasture's syndrome with massive pulmonary hemorrhage showing resistance to other conventional therapy."
01/01/2015 - "Based on renal biopsy, the diagnosis was finally confirmed as anti-GBM disease combined with IgA nephropathy and, the patient received comprehensive treatment, including cyclophosphamide (CTX), which led to symptom improvement. "
08/01/1999 - "[A case of Goodpasture's syndrome with massive pulmonary hemorrhage ameliorated by cyclophosphamide pulse therapy]."
01/01/2014 - "The treatment of anti-GBM disease and GPA both involve immunosuppression with prednisone and cyclophosphamide. "
01/01/2013 - "In the current study, we investigated the associations between anti-C1q antibodies in sera and C1q deposition in kidney of patients with anti-GBM disease. "
12/01/2015 - "Clinical features and detection of circulating anti-glomerular basal membrane antibodies first raise the possibility of a Goodpasture syndrome. "
05/01/2015 - "Interestingly, anti-complementary α3 antibodies were identified in sera from patients with anti-GBM disease, suggesting a role for 'autoantigen complementarity' in immunopathogenesis of the human disease. "
01/01/2015 - "16 patients with anti-GBM disease and positive anti-P14 antibodies were enrolled. "
07/01/2014 - "Type 1 includes cases of Goodpasture syndrome characterized by linear deposits of antibodies along the glomerular basement membrane (GBM) at immunofluorescence. "
|4.||Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
05/01/2015 - "The aim of this study was to determine the clinicopathologic predictors of patient and renal outcomes in anti-GBM disease with or without ANCA. "
06/01/2015 - "Clinicopathological diagnoses were ANCA-associated GN (74%), LN (18%), anti-GBM disease (5%) and HScP (3%). "
02/01/2015 - "The patient was diagnosed with anti-GBM disease associated with p-ANCA with MPO specificity. "
01/01/2014 - "Seronegative anti-GBM Disease with Coexistent ANCA Positivity."
10/27/2013 - "[Clinical consequence and significance of anti-neutrophil cytoplasmic antibody positivity in anti-glomerular basement membrane disease]."
04/01/1984 - "A patient with auto-antibody mediated Goodpasture's syndrome was successfully treated with cytotoxic drugs, steroids and plasma exchange. "
01/01/2010 - "He was diagnosed with Goodpasture's syndrome and treated with steroids, plasmapheresis, and hemodialysis. "
10/01/1984 - "Partial recovery of renal function in an oligoanuric patient affected with Goodpasture's syndrome after treatment with steroids, immunosuppressives and plasmapheresis."
05/01/1981 - "Both were both in Puerto Rico and had left the island six to 15 years previously; both were receiving adrenal steroids (one for Hodgkin's disease and the other for Goodpasture's syndrome). "
03/01/2007 - "The combination of plasmapheresis with these cytotoxic agents and steroids is effective in patients with Goodpasture's syndrome, especially if instituted early in the course of the disease. "
|6.||Immunoglobulin G (IgG)IBA
01/01/2013 - "In the current study, we investigated the deposition of the four IgG subclasses using immunohistochemistry in the renal biopsy specimens from 46 patients with anti-GBM disease. "
05/01/1988 - "Direct immunofluorescence studies of tissue from a patient with Goodpasture's syndrome revealed deposition of IgG in the choroid plexus and eye, as well as in the kidney and lung."
10/01/2015 - "The kidney biopsy demonstrates crescentic GN on light microscopy (LM) and strong pseudo-linear/globular glomerular basement membrane (GBM) staining for immunoglobulin G on immunofluorescence (IF), suggestive of anti-GBM disease. "
01/01/2014 - "There was bright linear glomerular basement membrane staining with IgG consistent with anti-GBM disease. "
01/01/2014 - "The fewer plasma-associated side effects and reduced loss of IgG suggest that DFPP may be a better treatment choice for anti-GBM disease, especially in patients with insufficient plasma."
|7.||Idiopathic pulmonary hemosiderosisIBA
03/01/1990 - "[Goodpasture syndrome, idiopathic pulmonary hemosiderosis]."
07/01/1989 - "Goodpasture's syndrome mimicking idiopathic pulmonary hemosiderosis."
01/01/1977 - "The close relation to idiopathic pulmonary hemosiderosis and Goodpasture's syndrome is emphasized."
01/01/1977 - "Description of roentgenographic changes in idiopathic pulmonary hemosiderosis and Goodpasture's syndrome. "
01/01/1977 - "[Idiopathic pulmonary hemosiderosis and Goodpasture's syndrome -- radiological findings (author's transl)]."
|8.||Antigen-Antibody Complex (Immune Complex)IBA
01/01/2006 - "The immune complexes deposited in glomeruli might participate in the initiation of anti-GBM disease."
01/01/2006 - "Clinical and pathological data of patients with immune complex deposition (n = 10) were compared with those of patients with anti-GBM disease alone (n = 37). "
01/01/2006 - "In the current series, glomerular immune complexes were identified in 10 of 47 patients who presented with renal-biopsy-proven anti-GBM disease. "
01/01/2006 - "However, the concurrent glomerular immune complex deposition was not rare and might be contributed to the development of anti-GBM disease. "
08/01/1989 - "In the series, glomerular immune complexes were identified in 6 of 17 patients who initially presented with anti-GBM disease. "
|9.||Immunoglobulin A (IgA)IBA
08/01/2013 - "The IgA variant of anti-GBM disease has rarely been described. "
08/01/2013 - "An unusual case of IgA-mediated anti-glomerular basement membrane disease."
05/01/2012 - " We report a rare case of a 31-year-old female who was diagnosed as having anti-GBM disease with extensive IgA deposits in the mesangium. "
05/01/2012 - "Mesangial IgA deposits indicate pathogenesis of anti-glomerular basement membrane disease."
09/01/1999 - "The emerging spectrum of IgA-mediated renal diseases: is there an IgA variant of Goodpasture's syndrome?"
|10.||alemtuzumab (Campath)FDA Link
01/01/2013 - "Close monitoring for potential side effects of alemtuzumab treatment in RRMS resulted in a positive outcome when anti-GBM disease was recognized and treated early."
01/01/2013 - "A 35-year-old white female receiving alemtuzumab for RRMS in a clinical research protocol developed symptoms leading to diagnosis of anti-GBM disease. "
12/04/2008 - "More on anti-glomerular basement membrane disease after alemtuzumab."
08/14/2008 - "Anti-glomerular basement membrane disease after alemtuzumab."
01/01/2013 - "Case report of anti-glomerular basement membrane disease following alemtuzumab treatment of relapsing-remitting multiple sclerosis."
01/01/2013 - "Plasmapheresis is beneficial for patients with Goodpasture's syndrome and those with severe pauci-immune GN. "
01/01/2014 - "However, patients with anti-GBM disease are also treated with plasmapheresis early in the disease presentation to prevent further damage. "
01/01/2012 - "Because the findings of renal biopsy suggested anti-GBM disease, the patient was treated with plasmapheresis and pulse steroid therapy, which resulted in a rapid resolution of his pulmonary symptoms and chest radiograph abnormalities. "
10/01/2010 - "During his stay, the patient underwent treatment with plasmapheresis, and an open lung biopsy, which confirmed the diagnosis of anti-GBM disease. "
08/01/2009 - "Here, we report a case of Goodpasture's syndrome that we treated with double filtration plasmapheresis (DFPP) combined with immunosuppression therapy. "
12/01/2011 - "Treatment of choice for Goodpasture's syndrome is immunosuppressive therapy and plasma exchange, which has greatly improved morbidity and mortality. "
04/01/2015 - "The benefit of plasma exchange is unquestionable in Goodpasture's syndrome. "
04/01/2010 - "Plasma exchange for Goodpasture syndrome."
04/01/2007 - "In 1976, Lockwood demonstrated the place of plasma exchanges (PE) in Goodpasture's syndrome [Lockwood CM, Rees AJ, Pearson TA, Evans DJ, Peters DK, Wilson CB. "
01/26/1985 - "Plasma exchange in Goodpasture's syndrome."
|3.||Blood Component Removal (Apheresis)
05/01/2003 - "These results suggest that granulocyte and monocyte apheresis may be of benefit in the therapy of a patient with ulcerative colitis who previously had Goodpasture syndrome"
07/01/2003 - "Apheresis has dramatically improved the prognosis and outcome in patients with myasthenia gravis, Guillain-Barré syndrome, Goodpasture syndrome and thrombotic thrombocytopenic purpura. "
02/01/2013 - "Over the last 4 decades, modern therapeutic apheresis has been used clinically for the treatment of a host of renal, hematological, and neurological diseases such as Goodpasture's syndrome, thrombotic thrombocytopenic purpura, and myasthenia gravis to name a few (Ibrahim et al., Pharmacotherapy 2007;27:1529-1549). "
01/01/1983 - "Apheresis can be useful in the treatment of many other disorders, most notably myasthenia gravis, glomerulonephritis associated with hemoptysis (Goodpasture's syndrome), refractory systemic lupus erythematosus, cryoglobulinemia and immune cytopenic disorders."
02/01/2013 - "Apheresis has been used particularly in children with certain renal diseases, notably ANCA-associated nephritis, anti-GBM disease, and atypical HUS. "
12/01/2014 - "Post-transplant anti-GBM disease was rare."
12/01/2014 - "One Alport patient (0.4%) had post-transplant anti-glomerular basement membrane (anti-GBM) disease. "
01/01/2013 - "Posttransplant antiglomerular basement membrane (anti-GBM) disease occurs in approximately 5% of Alport patients and usually ends in irreversible graft failure. "
06/01/2012 - "We describe what is, to the best of our knowledge, the first case of man who successfully underwent a kidney transplant with preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome."
06/01/2012 - "Kidney transplant after preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome."
|5.||Tissue Therapy (Cell Therapy)