This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
Also Known As:
p56 lck; Proto-Oncogene Protein c-lck; Proto-Oncogene Protein lck; Kinase, lck; Protein c-lck, Proto-Oncogene; Protein lck, Proto-Oncogene; Proto Oncogene Protein c lck; Proto Oncogene Protein lck; c-lck, Proto-Oncogene Protein; lck, Proto-Oncogene Protein; Protein Tyrosine Kinase p56(lck); lck Kinase