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Proto-Oncogene Proteins c-met

Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.
Also Known As:
MET Proto-Oncogene, Receptor Tyrosine Kinase; MET Receptor Tyrosine Kinase; Receptor, HGF; Receptor, Hepatocyte Growth Factor; Receptor, Scatter Factor; Scatter Factor Receptor; c-Met Receptor Tyrosine Kinase; MET Proto Oncogene, Receptor Tyrosine Kinase; Proto Oncogene Proteins c met; Proto-Oncogene Proteins, met; c Met Receptor Tyrosine Kinase; c met Proteins; met Proto Oncogene Proteins; HGF Receptor; Hepatocyte Growth Factor Receptor; c-met Proteins; met Proto-Oncogene Proteins
Networked: 714 relevant articles (10 outcomes, 82 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Salgia, Ravi: 17 articles (12/2020 - 02/2002)
2. Nakamura, Toshikazu: 15 articles (10/2010 - 08/2002)
3. Matsumoto, Kunio: 14 articles (01/2022 - 08/2002)
4. Zimmer, Yitzhak: 13 articles (01/2020 - 11/2003)
5. Medová, Michaela: 12 articles (01/2020 - 02/2012)
6. Levitt, Pat: 11 articles (01/2021 - 11/2006)
7. Christensen, James G: 11 articles (07/2012 - 09/2003)
8. Park, Morag: 10 articles (01/2020 - 02/2003)
9. Aebersold, Daniel M: 9 articles (01/2020 - 11/2003)
10. Comoglio, Paolo M: 8 articles (12/2014 - 08/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Lung Neoplasms (Lung Cancer)
4. Colorectal Neoplasms (Colorectal Cancer)
5. Melanoma (Melanoma, Malignant)

Related Drugs and Biologics

1. ErbB Receptors (EGF Receptor)
2. Hepatocyte Growth Factor (Growth Factor, Hepatocyte)
3. Tyrosine Kinase Inhibitors
4. Ligands
5. Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
6. Plasminogen Activator Inhibitor 1
7. Glucose (Dextrose)
8. quinoline
9. Phosphotransferases (Kinase)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Nanospheres
3. Radiotherapy
4. Ligation
5. Gastrectomy