|1.||Humphreys, Michael H: 8 articles (08/2009 - 04/2003)|
|2.||Ni, Xi-Ping: 5 articles (08/2009 - 04/2003)|
|3.||Pearce, David: 2 articles (08/2009 - 04/2003)|
|4.||Perretti, Mauro: 2 articles (12/2008 - 11/2006)|
|5.||Grieco, Paolo: 2 articles (12/2008 - 11/2006)|
|6.||Getting, Stephen J: 2 articles (12/2008 - 11/2006)|
|7.||Cone, Roger D: 2 articles (11/2006 - 04/2003)|
|8.||Butler, Andrew A: 2 articles (11/2006 - 04/2003)|
|9.||van Dijk, Claudia: 1 article (08/2009)|
|10.||Ni, X-P: 1 article (12/2008)|
|1.||Hypertension (High Blood Pressure)
04/01/2003 - "gamma-MSH deficiency results in marked salt-sensitive hypertension that is rapidly improved with exogenous gamma-MSH through a central site of action. "
08/01/2007 - "To study the time course, and establish the causal role, of gamma-MSH deficiency in the development of salt-sensitive hypertension, we instrumented 12 male Sprague-Dawley rats with radiotelemetry transmitters to record intraaortic mean arterial pressure (MAP). "
08/01/2007 - "Prevention of salt-induced hypertension by an analog of gamma-melanocyte-stimulating hormone in the rat."
01/01/2007 - "In contrast, gamma-MSH deficiency in rodents, or disruption of MC3R, leads to marked salt-sensitive hypertension, again through a central mechanism: a small dose of exogenous peptide delivered into the cerebroventricular system of mice with gamma-MSH deficiency restores blood pressure to normal. "
03/01/2004 - "Genetic or pharmacologic induction of gamma-MSH deficiency results in marked salt-sensitive hypertension that is corrected by the administration of the peptide, probably through a central site of action. "
02/01/1994 - "A significantly greater 57% reduction in fever was observed when the intraseptal microinfusion of gamma-MSH was combined with electrical stimulation of the PVN (for parameters see above). "
02/01/1994 - "A systemic infusion of 0.261 mumol gamma-MSH for 6 h reduced LPS fever to approximately 50% compared with animals infused with vehicle (0.9% saline).(ABSTRACT TRUNCATED AT 250 WORDS)"
02/01/1994 - "Intraseptal microinfusions of gamma-MSH at a concentration of 10(-5) mol/l for 6 h with an infusion speed of 0.1 microliter/min caused a 38% reduction in fever. "
02/01/1994 - "This reduction in fever by electrical PVN stimulation was partly reversed by a simultaneous intraseptal microinfusion of the vasopressinergic V1-receptor antagonist d(CH2)5[Tyr(Met)2]AVP at a concentration of 10(-5) mol for 6 h with an infusion speed of 0.1 microliter/min. We further investigated the effects of intraseptal microinfusions or systemic infusions of the gamma-melanocyte-stimulating hormone (gamma-MSH), a derivative of the proopiomelanocortin, on LPS-induced fever. "
|3.||Melanoma (Melanoma, Malignant)
11/17/2003 - "It is also reported to influence melanoma invasion with levels of alpha-, beta- and gamma-MSH correlated clinically with malignant melanoma development, but other studies suggest alpha-MSH acts to retard invasion. "
01/01/1992 - "Thus, gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion."
01/01/1992 - "Melanotropic activity of gamma MSH peptides in melanoma cells."
07/01/1985 - "In plasmas sampled at 1200 h, IR-gamma-MSH was significantly higher in patients with IHA (95 +/- 26 fmol/ml) and adenomas (63 +/- 23 fmol/ml), as compared with essential hypertensives (31 +/- 6 fmol/ml) and normotensives (19 +/- 3 fmol/ml). "
07/01/1985 - "In the present study, plasma immunoreactive (IR-) gamma-MSH levels at 0800 h in patients with IHA were evaluated (90 +/- 17 fmol/ml; range: 13-173 fmol/ml) and found to be significantly higher (P less than 0.05) than those in subjects with aldosterone-producing adenomas (33 +/- 8 fmol/ml), essential hypertension (33 +/- 6 fmol/ml), and normotensive controls (19 +/- 2 fmol/ml). "
07/01/1985 - "In order to evaluate the effect of a pro-gamma-MSH in vitro, adrenal adenoma tissue was obtained from two patients, one with elevated IR-gamma-MSH (61 fmol/ml) and a second with low IR-gamma-MSH (12 fmol/ml). "
07/01/1985 - "Plasma immunoreactive gamma melanotropin in patients with idiopathic hyperaldosteronism, aldosterone-producing adenomas, and essential hypertension."
|5.||Pituitary Neoplasms (Pituitary Adenoma)
08/01/1982 - "Characterization of gamma-melanotropin-like immunoreactivity and its secretion in an adrenocorticotropin-producing mouse pituitary tumor cell line."
11/01/1985 - "Finally there are presented the characterization of gamma-MSH, the hypothermic effect of intracisternal administration of gamma-MSH, the effect of corticortropin releasing factor on increased secretion of alpha-MSH from rat pituitary, and the effect of arginine vasopressin on secretion of alpha-MSH from pituitary adenoma."
08/01/1982 - "gamma MSH, a putative hormone in the N-terminal region of the ACTH/beta-endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. "
01/01/1981 - "These results indicate that 1) ACTH-producing human pituitary adenomas concomitantly secrete ACTH, beta-LPH, beta-EP, and big gamma-MSH, and 2) lysine vasopressin, MEE, TRH, and LRH act directly on pituitary cells to stimulate the release of these peptides."
01/01/1981 - "The cells of the two pituitary adenomas stained with antisera against beta-endorphin and against pro-gamma-melanotropin, the NH2-terminal fragment of the corticotropin-beta-lipotropin precursor, but not with antisera against alpha-melanotropin or beta-lipotropin. "
|4.||Adrenocorticotropic Hormone (ACTH)
|5.||beta-Endorphin (Endorphin, beta)
|10.||Melanocyte-Stimulating Hormones (MSH)
|1.||Surgical Instruments (Clip)
|2.||Pneumonectomy (Lung Volume Reduction)
|4.||Drug Therapy (Chemotherapy)