|1.||Chen, Ing-Jun: 5 articles (01/2015 - 03/2010)|
|2.||Wu, Bin-Nan: 4 articles (05/2014 - 03/2010)|
|3.||Martin, Richard J: 4 articles (01/2013 - 07/2004)|
|4.||Yeh, Jwu-Lai: 3 articles (01/2015 - 03/2010)|
|5.||Dai, Zen-Kong: 3 articles (05/2014 - 03/2010)|
|6.||Dua, Pooja: 3 articles (07/2008 - 08/2006)|
|7.||Gude, Rajiv P: 3 articles (07/2008 - 08/2006)|
|8.||Marinello, E: 3 articles (06/2008 - 02/2001)|
|9.||Takahashi, S: 3 articles (10/2005 - 01/2000)|
|10.||Yamamoto, T: 3 articles (10/2005 - 01/2000)|
|1.||Asthma (Bronchial Asthma)
08/01/1998 - "It is concluded that study of xanthine derivatives in asthmatics might help the development of asthma therapy. "
04/01/2006 - "Pediatricians and family physicians appeared to share similar opinions on the medical management of children with asthma in that both most commonly prescribed oral beta2-agonists and xanthine derivatives, either alone or in combination. "
11/01/1994 - "Long-term xanthine therapy of asthma. "
03/01/1985 - "Bronchodilator actions of xanthine derivatives administered by inhalation in asthma."
05/01/1977 - "Oral administration of xanthine compounds represents the first line of therapy in most patients with asthma. "
12/01/1991 - "The possibility that this ischemia and reperfusion-induced damage can be reduced by preischemic application of a xanthine derivative (pentoxiphylline) was examined using 31P NMR spectroscopy and electron microscopy (EM) studies of bioenergetic and ultrastructural changes in oxygenated erythrocyte-perfused rat livers. "
04/27/2002 - "Preconditioning reduced xanthine accumulation and conversion of XDH to XOD in liver during sustained ischemia. "
10/01/1993 - "Xanthine was the only biochemical where an increase appeared to correlate with ischemia duration while energy charge was of no value in indicating injury extent. "
02/01/1989 - "Xanthine level was still high 8 hours after ischemia and then rapidly decreased to the normal value at day 2.(ABSTRACT TRUNCATED AT 250 WORDS)"
02/01/1989 - "In the ischemic hemisphere, xanthine increased up to 57.7 +/- 5.2 nmol/g tissue 2 hours after MCA occlusion and reached a maximum value of 59.42 +/- 4.91 nmol/g tissue 4 hours following the induction of ischemia. "
10/01/2011 - "It has become apparent that XOR possesses multi-functional enzymatic activities outside the realm of xanthine metabolism and a small but significant literature also established a compelling functional association between administered sodium nitrite, XOR activation, and pharmacologically characterized NO transductive effects in positive cardiovascular function enhanced pulmonary perfusion, and protection against ischemia/reperfusion injury and hypoxic damage and oxidative stress. "
08/01/1989 - "The purpose of this study was to evaluate the possible involvement of xanthine and xanthine oxidase in reperfusion injury in a low-flow, reflow model of liver perfusion. "
02/01/1998 - "However, this role for human XO is disputed due to its distinctive lack of activity towards xanthine, and the failure of allopurinol to suppress reperfusion injury. "
11/01/1988 - "Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury."
02/01/1989 - "Xanthine and hypoxanthine accumulation during storage may contribute to reperfusion injury following liver transplantation in the rat."
04/27/2002 - "Preconditioning, by blocking the xanthine/XOD pathway for ROS generation, would confer protection against the liver and lung injuries induced by hepatic I/R."
12/01/1999 - "This study was designed to clarify the role of intrapulmonary neutrophils in the development of xanthine/xanthine oxidase (X/XO)-induced lung injury in isolated buffer-perfused rabbit lungs. "
04/01/1995 - "Moreover, we determined the salutary effects of HWA 138, a new xanthine derivative, against endotoxin-related lung injury. "
01/01/1989 - "In the present study, the possible protective effects were examined of an analogue of pentoxifylline, HWA-138, a xanthine derivative, on lung injury in septic guinea-pigs. "
06/01/1994 - "We investigated the role of free radicals, especially from activated neutrophils, in acute xanthine and xanthine oxidase-induced lung injury in rats. "
|5.||Brain Ischemia (Cerebral Ischemia)
10/01/1992 - "The xanthine derivative propentofylline (HWA 285) has been reported to show protective effects against neuronal damage induced by cerebral ischemia. "
03/01/1992 - "The xanthine derivative propentofylline (HWA 285) has been reported to show protective effects against neuronal damage induced by cerebral ischemia. "
09/01/1989 - "The possible involvement of the xanthine-xanthine oxidase system in initiating free radical reactions in cerebral ischemia is also discussed."
12/01/1988 - "Changes of the xanthine and uric acid (UA) levels in rat forebrain following focal cerebral ischemia were studied by reversed-phase HPLC with electrochemical detection. "
09/24/1991 - "Previous studies have demonstrated that the xanthine compound, propentofylline, has beneficial effects in models of cerebral ischemia and can enhance some and exhibit other effects of adenosine. "
|6.||Reactive Oxygen Species (Oxygen Radicals)
|9.||Uric Acid (Urate)
|1.||Kampo Medicine (Kampo)
|3.||Transplantation (Transplant Recipients)
|4.||Drug Therapy (Chemotherapy)