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Sodium Azide

A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed)
Also Known As:
Azide, Sodium; NaN3
Networked: 221 relevant articles (3 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lardelli, Michael: 3 articles (10/2014 - 07/2011)
2. Moussavi Nik, Seyyed Hani: 3 articles (10/2014 - 07/2011)
3. Siniscalchi, Anna: 3 articles (08/2013 - 12/2006)
4. Marino, Silvia: 3 articles (08/2013 - 12/2006)
5. Voĭnikov, V K: 3 articles (04/2004 - 05/2001)
6. Rusaleva, T M: 3 articles (04/2004 - 05/2001)
7. Rachenko, E I: 3 articles (04/2004 - 05/2001)
8. Varakina, N N: 3 articles (04/2004 - 05/2001)
9. Rikhvanov, E G: 3 articles (04/2004 - 05/2001)
10. Seo, Jung-Woo: 2 articles (01/2015 - 08/2013)

Related Diseases

1. Chromosome Aberrations (Chromosome Abnormalities)
2. Infertility (Sterility)
3. Bovine Brucellosis (Bang's Disease)
4. Anoxia (Hypoxia)
5. Neurodegenerative Diseases (Neurodegenerative Disease)
05/11/2001 - "Therefore, chronic nonlethal sodium azide administration may provide a potential rat model for the study of mitochondrial dysfunction and the role of environmental pollutants in brain and muscle tissues affected in certain neurodegenerative diseases."
10/01/2000 - "To study the role of mitochondrial deficiency in the pathogenesis of neurodegenerative disease by investigating the energy metabolism in a sodium azide inhibited cytochrome-c oxidase SH-SY5Y Cell model. "
01/01/1999 - "Since energy-dependent secondary excitotoxic mechanisms also account for the pathogenesis of neurodegenerative diseases, a study was made of the effects of sodium azide on the immunohistochemical localization of kynurenine aminotransferase-I. After in vivo administration of sodium azide for five days, a markedly decreased glial kynurenine aminotransferase-I immunoreactivity was found by immunohistochemical techniques in the glial cells of the striatum, hippocampus, dentate gyrus and temporal cortex; at the same time, kynurenine aminotransferase-I started to be expressed by nerve cells which had not been immunoreactive previously. "
08/01/2013 - "Primary cortical neurons exposed to the mitochondrial toxin NaN3 (0.1-3 mM) were submitted to oxidative stress with H2O2 (30-150 μM), to mimic conditions observed in neurodegenerative disorders. "
05/11/2001 - "Effects of chronic sodium azide on brain and muscle cytochrome oxidase activity: a potential model to investigate environmental contributions to neurodegenerative diseases."

Related Drugs and Biologics

1. Curcumin
2. Peroxidase (Myeloperoxidase)
3. Alkaline Phosphatase
4. Sodium Azide
5. Adenosine Triphosphate (ATP)
6. Glucose (Dextrose)
7. Electron Transport Complex IV (Cytochrome c Oxidase)
8. Etoposide (VP 16)
9. triethylenediamine (DABCO)
10. Diazoxide (Hyperstat)

Related Therapies and Procedures

1. Microspheres (Microsphere)
2. Air Bags (Airbags)
3. Photochemotherapy (Photodynamic Therapy)
4. Lasers (Laser)
5. Injections