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Topotecan (Hycamtin)

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
Also Known As:
Hycamtin; 9-Dimethylaminomethyl-10-hydroxycamptothecin; Hycamtamine; NSC-609699; Nogitecan Hydrochloride; SK&F-104864-A; SKF-104864-A; SmithKline Beecham Brand of Topotecan Hydrochloride; Topotecan Hydrochloride; Topotecan Monohydrochloride, (S)-Isomer; 9 Dimethylaminomethyl 10 hydroxycamptothecin; Hydrochloride, Nogitecan; Hydrochloride, Topotecan; NSC 609699; NSC609699; SK&F 104864 A; SK&F104864A; SKF 104864 A; SKF104864A
Networked: 1462 relevant articles (193 outcomes, 590 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Stewart, Clinton F: 27 articles (09/2015 - 03/2002)
2. Abramson, David H: 14 articles (10/2015 - 08/2007)
3. Pommier, Yves: 12 articles (12/2014 - 08/2002)
4. Coleman, Robert L: 11 articles (12/2015 - 01/2002)
5. Schaiquevich, Paula: 11 articles (10/2015 - 11/2007)
6. Sugimoto, Yoshikazu: 11 articles (07/2011 - 03/2002)
7. Herzog, Thomas J: 11 articles (03/2011 - 01/2002)
8. Monk, Bradley J: 9 articles (03/2015 - 07/2005)
9. Doroshow, James H: 9 articles (12/2014 - 02/2010)
10. Chantada, Guillermo L: 9 articles (09/2014 - 03/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Ovarian Neoplasms (Ovarian Cancer)
3. Small Cell Lung Carcinoma (Small Cell Lung Cancer)
4. Carcinoma (Carcinomatosis)
5. Neuroblastoma

Related Drugs and Biologics

1. Paclitaxel (Taxol)
2. Cisplatin (Platino)
3. Platinum
4. Carboplatin (JM8)
5. Type I DNA Topoisomerases (Topoisomerase I)
6. irinotecan (Camptosar)
7. Etoposide (VP 16)
8. Cyclophosphamide (Cytoxan)
9. gemcitabine
10. Doxorubicin (Adriamycin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Radiotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Stem Cell Transplantation