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Thrombospondin 1

An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
Also Known As:
1, Thrombospondin; TSP-1
Networked: 561 relevant articles (13 outcomes, 90 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lawler, Jack: 26 articles (02/2015 - 01/2002)
2. Roberts, David D: 8 articles (07/2015 - 12/2007)
3. Masli, Sharmila: 7 articles (09/2015 - 04/2004)
4. Gutierrez, Linda S: 7 articles (05/2015 - 02/2003)
5. Frangogiannis, Nikolaos G: 6 articles (10/2014 - 06/2005)
6. Tuszynski, George P: 6 articles (01/2010 - 08/2002)
7. Taraboletti, Giulia: 5 articles (10/2015 - 12/2003)
8. Martiny, Laurent: 5 articles (01/2015 - 03/2005)
9. Ryeom, Sandra: 5 articles (04/2014 - 10/2006)
10. Rak, Janusz: 5 articles (04/2013 - 08/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Fibrosis (Cirrhosis)
3. Carcinoma (Carcinomatosis)
4. Neoplasm Metastasis (Metastasis)
5. Thyroid Neoplasms (Thyroid Cancer)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Transforming Growth Factor beta1 (TGF beta 1)
3. Endostatins
4. Epidermal Growth Factor (EGF)
5. Collagen
6. Intercellular Signaling Peptides and Proteins (Growth Factors)
7. Alkalies
8. Transforming Growth Factor beta (TGF-beta)
9. Messenger RNA (mRNA)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Lasers (Laser)
3. Injections
4. Refractive Surgical Procedures
5. Transplants (Transplant)