|1.||Lu, Kun Ping: 19 articles (04/2015 - 01/2003)|
|2.||Zhou, Xiao Zhen: 9 articles (04/2015 - 02/2006)|
|3.||Choi, Hong Seok: 7 articles (06/2015 - 05/2008)|
|4.||Wulf, Gerburg: 7 articles (04/2015 - 01/2003)|
|5.||Fischer, Gunter: 7 articles (01/2015 - 01/2003)|
|6.||Ryo, Akihide: 6 articles (04/2009 - 01/2003)|
|7.||Chen, Chun-Hau: 5 articles (04/2015 - 04/2011)|
|8.||Kang, Keon Wook: 5 articles (06/2014 - 05/2008)|
|9.||Del Sal, Giannino: 5 articles (12/2013 - 07/2004)|
|10.||Uchida, Takafumi: 5 articles (03/2011 - 01/2003)|
08/01/2003 - "Infection studies with these strains revealed that the N-terminal part and the dimerization of Mip but not its PPIase activity are necessary for full virulence in Acanthamoeba castellanii. "
01/01/2015 - "pneumophila, the PPIase activity of Mip is required for invasion of macrophages, transmigration through an in vitro lung-epithelial barrier, and full virulence in the guinea pig infection model. "
02/01/2014 - "[The role of peptidyl-prolyl-Cis/trans-isomerase Genes of Arabidopsis thaliana in plant defense during the course of Xanthomonas campestris infection]."
08/01/2012 - "We investigated the effects of nonsynonymous single nucleotide polymorphisms (SNPs) in the region of peptidyl-prolyl isomerase A (PPIA) that encodes CypA on HCV infection and replication of human hepatocytes. "
09/01/2011 - "A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei."
07/02/2009 - "In this study, we showed a strong correlation between the expression levels of an oncogenic peptidyl-prolyl cis/trans isomerase Pin1 and levels of Akt phosphorylation at S473 in multiple cancer types (P<0.0001). "
10/23/2015 - "Prolyl isomerase Pin1 plays an important role in cell proliferation and is overexpressed in many human tumors. "
06/01/2015 - "Pin1, a conserved eukaryotic Peptidyl-prolyl cis/trans isomerase, has profound effects on numerous key-signaling molecules, and its deregulation contributes to disease, particularly cancer. "
09/01/2014 - "Prolyl isomerase Pin1 in cancer."
08/01/2014 - "[Pin1: a multi-talented peptidyl prolyl cis-trans isomerase and a promising therapeutic target for human cancers]."
|3.||Alzheimer Disease (Alzheimer's Disease)
05/23/2007 - "Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease."
04/01/2015 - "The unique proline isomerase Pin1 is pivotal for protecting against age-dependent neurodegeneration in Alzheimer's disease (AD), with its inhibition providing a molecular link between tangle and plaque pathologies. "
09/01/2013 - "The enzyme peptidyl-prolyl cis-trans isomerase (Pin1) may play an important role in preventing the development of Alzheimer's disease (AD). "
01/01/2009 - "Peptidyl-prolyl isomerase, NIMA-interacting 1 (PIN1) plays a significant role in the brain and is implicated in numerous cellular processes related to Alzheimer's disease (AD) and other neurodegenerative conditions. "
05/01/2006 - "Among abnormal Tau phosphorylation sites, pThr231 is of particular interest since it is associated with early stages of Alzheimer's disease and is a binding site of Pin1, a peptidyl-prolyl cis/trans isomerase mainly involved in cell cycle regulation. "
|4.||Breast Neoplasms (Breast Cancer)
01/01/2008 - "The goal of this study was to examine the expression of prolyl isomerase Pin1 in human Her2+ breast cancer, and to study if Pin1 affects the expression of Her2/Neu itself. "
06/01/2015 - "COT phosphorylates prolyl-isomerase Pin1 to promote tumorigenesis in breast cancer."
11/01/2013 - "Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer."
03/21/2013 - "Here, we identify prolyl isomerase Pin1, which is often overexpressed in breast cancer, as a key regulator of RUNX3 inactivation. "
01/01/2008 - "Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability."
|5.||Hepatocellular Carcinoma (Hepatoma)
01/01/2015 - "Peptidyl-Prolyl cis/trans Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma."
08/01/2012 - "Then, we demonstrated that CypB overexpression protects human hepatoma cells against oxidative stress through its binding to CD147; this protective effect depends on the peptidyl prolyl isomerase activity of CypB. "
03/01/2007 - "The peptidyl prolyl isomerase Pin1 frequently is overexpressed in hepatocellular carcinoma (HCC). "
09/01/2006 - "The phospho-Ser/Thr-Pro specific prolyl-isomerase PIN1 is over-expressed in more than 50% of hepatocellular carcinomas (HCCs). "
08/01/1983 - "Systematic fractionation of subcellular components revealed that 92% of the total PPiase activity of rat liver and 97.5% of that of Hepatoma 3924A were in the cytosol. "
|2.||Peptidylprolyl Isomerase (Prolyl Isomerase)
|3.||TATA-Box Binding Protein (TATA-Binding Protein)
|4.||tributyl phosphate (TBP)
|5.||Ribosomal Proteins (Ribosomal Protein)
|8.||Messenger RNA (mRNA)
|2.||Prostatectomy (Retropubic Prostatectomy)