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Loss of Heterozygosity

The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.
Also Known As:
Allelic Losses; Heterozygosity Loss; Allelic Loss; Heterozygosity, Loss of
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