Replacement Arthroplasty

Partial or total replacement of a skeletal joint.

Also Known As:

Arthroplasty, Replacement; Arthroplasties, Replacement; Joint Replacement; Replacement Arthroplasties; Total Joint Replacement; Implantation, Joint Prosthesis; Implantations, Joint Prosthesis; Joint Prosthesis Implantations; Joint Replacement, Total; Joint Replacements; Joint Replacements, Total; Prosthesis Implantation, Joint; Prosthesis Implantations, Joint; Replacement, Joint; Replacement, Total Joint; Replacements, Joint; Replacements, Total Joint; Total Joint Replacements; Joint Prosthesis Implantation

Networked: 3421 relevant articles (150 outcomes, 327 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913

Experts

1.	Goodman, Stuart B: 38 articles (01/2022 - 06/2003)
2.	Katz, Jeffrey N: 21 articles (01/2021 - 12/2002)
3.	Graves, Stephen E: 20 articles (05/2022 - 04/2012)
4.	Lorimer, Michelle: 19 articles (05/2022 - 10/2014)
5.	Yao, Zhenyu: 19 articles (01/2021 - 05/2012)
6.	Schwarzkopf, Ran: 18 articles (10/2022 - 11/2012)
7.	Pajarinen, Jukka: 18 articles (01/2021 - 11/2013)
8.	Graves, Stephen: 15 articles (01/2022 - 01/2009)
9.	Wluka, Anita E: 14 articles (10/2021 - 01/2009)
10.	de Steiger, Richard N: 13 articles (07/2022 - 01/2015)

Related Diseases

1.	Pain (Aches) 07/18/2007 - "Most studies showed improvement of the patient (less pain and improvement of function scores) after osteotomy surgery, but in the majority of the studies there was no significant difference with other operative treatment (other technique of HTO/ unicompartmental joint replacement). " 01/25/2005 - "Most studies showed improvement of the patient (less pain and improvement of function scores) after osteotomy surgery, but in the majority of the studies there was no significant difference with other operative treatment (other technique of HTO/ unicompartmental joint replacement). " 08/01/2010 - "Total joint replacement (TJR) of the hip and knee are extremely effective procedures, resulting in decreased pain and improved function and quality of life in patients of all age groups including the elderly. " 09/06/1999 - "Patients in each age group showed a significant improvement in health-related quality of life after joint replacement surgery in most scales of the SF-36, particularly physical function, role physical and bodily pain. " 03/01/2020 - "• This study reports the long term outcomes of hip and knee replacement surgery in late-stage OA.• We identified pre-, per-, and post-operative determinants which contribute to a greater improvement in pain and function, hence increasing patients' satisfaction.• These results could contribute to select an OA population which has a high probability to get an optimal benefit from total joint replacement."
2.	Osteoarthritis 09/01/2023 - "The demand on health systems for care of patients with osteoarthritis, including joint replacements, which are highly effective for late stage osteoarthritis in hips and knees, will rise in all regions, but might be out of reach and lead to further health inequity for individuals and countries unable to afford them. " 06/01/2020 - "Total joint replacement is one of the most effective treatments for osteoarthritis, while the aseptic loosening of artificial joint is a major complication leading to the joint replacement failure. " 01/01/2021 - "At a minimum of two-year follow up (range: 2-3.45 years), the patient cohort demonstrated significant improvement in postoperative functional scores (hip disability and osteoarthritis outcome score for joint replacement [HOOS JR.] and clinical scores (12-item short-form health survey [SF/VR-12]) (p<0.001). " 12/01/2020 - "Hip Injury and Osteoarthritis Outcome Score, Joint Replacement scores significantly improved from a mean of 50 preoperatively to 87 postoperatively (P < .001), and the Veterans Rand 12 Item Health Survey physical score improved from a mean of 31 preoperatively to 44 postoperatively (P < .001). " 01/01/2014 - "Using three risk-adjustment methods we evaluated whether co-morbidity derived from electronic hospital patient data provided significant improvement on age adjustment when predicting major outcomes following an elective total joint replacement (TJR) due to osteoarthritis. "
3.	Arthritis (Polyarthritis) 01/01/2023 - "Joint replacement surgery is the most effective treatment for end-stage arthritis. " 10/01/2018 - "Total joint replacement is a highly effective treatment for patients with end-stage arthritis. " 01/01/2013 - "Joint replacement is an option that has demonstrated significant improvement in the quality of life for individuals with severe arthritis. " 03/01/1985 - "Total joint replacement has significantly improved the treatment of patients with severe, disabling arthritis. " 04/01/2019 - "However, few have applied embodiment concepts in total joint replacement (TJR), an effective treatment for end-stage arthritis. "
4.	Infections 06/01/2010 - "Moreover, difficult randomized controlled trials must be conducted to determine the best treatment to minimize infections of total joint replacements and reduce morbidity and mortality." 11/01/2016 - "Joint replacements are currently the most effective treatment for severe joint conditions and although many of these procedures are successful, infection developing after the procedure is still an issue, requiring complex and expensive revisions. " 10/01/2022 - "Although progress is evident in the effective treatment of joint replacement-related infections, it still remains a serious issue in orthopedics. " 09/01/2007 - "When appropriate safety precautions are taken, ultraviolet lighting appears to be an effective way to lower the risk of infection in the operating room during total joint replacement surgery." 06/01/2020 - "Despite improved strategies to prevent prosthetic joint infection, as the total number of joint replacements increases, so does the absolute number of infections. "
5.	Knee Injuries (Knee Injury) 11/07/2023 - "The Kujala score and Knee Injury and Osteoarthritic Outcome Score for Joint Replacement (KOOS, JR) were analyzed by group. " 09/01/2023 - "Outcomes included the Knee Injury and Osteoarthritic Outcome Score for Joint Replacement (KOOS, JR), Kujala, proportions of knees achieving the patient acceptable symptom state (PASS) for these scores, and survivorship. " 06/20/2023 - "Two-year follow-up data and patient-reported outcomes including knee injury and operative outcome scores, joint replacement scores (KOOS, JR) were available for 53 patients in the CaP group and 30 patients in the knee arthroscopy group. " 01/01/2022 - "Knee Injury and Osteoarthritis Outcome Score for Joint Replacement improved similarly (P = .62) for patients with optimal resurfacing (48.5-77.6 points) and non-optimal resurfacing (47.7-76.6 points). " 01/01/2022 - "Knee Injury and Osteoarthritis Outcome Score for Joint Replacement scores for the experimental group showed significant improvement at 2 and 8 weeks postsurgery (P < .05). "

Related Drugs and Biologics

1.	Metals
2.	Anti-Bacterial Agents (Antibiotics)
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4.	Enoxaparin (Lovenox)
5.	Opioid Analgesics (Opioids)
6.	Gentamicins (Gentamicin)
7.	Oxycodone (Oxycontin)
8.	Tapentadol
9.	Steroids
10.	Aspirin (Acetylsalicylic Acid)

Related Therapies and Procedures

1.	Osteotomy
2.	Prostheses and Implants (Prosthesis)
3.	Analgesia
4.	Arthroplasty
5.	Therapeutics