Intracranial Hypotension

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88 relevant articles (2 outcomes, 1 trials/studies) found for this Disease

Description: Reduction of CEREBROSPINAL FLUID pressure characterized clinically by HEADACHE which is maximal in an upright posture and occasionally by an abducens nerve palsy (see ABDUCENS NERVE DISEASES), neck stiffness, hearing loss (see DEAFNESS); NAUSEA; and other symptoms. This condition may be spontaneous or secondary to SPINAL PUNCTURE; NEUROSURGICAL PROCEDURES; DEHYDRATION; UREMIA; trauma (see also CRANIOCEREBRAL TRAUMA); and other processes. Chronic hypotension may be associated with subdural hematomas (see HEMATOMA, SUBDURAL) or hygromas. (From Semin Neurol 1996 Mar;16(1):5-10; Adams et al., Principles of Neurology, 6th ed, pp637-8)

Also Known As:

Essential Intracranial Hypotension; Hypotension, Essential Intracranial; Hypotension, Intracranial; Hypotension, Secondary Intracranial; Hypotension, Spontaneous Intracranial; Secondary Intracranial Hypotension; Spontaneous Intracranial Hypotension; Intracranial Hypotension, Essential; Intracranial Hypotension, Secondary; Intracranial Hypotension, Spontaneous

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3424

Central Nervous System Diseases: 931

Brain Diseases: 1121

Intracranial Hypotension: 88

Related Diseases

1.	Syndrome
2.	Headache (Headaches)
3.	Hypertension (High Blood Pressure)
4.	Heat Stroke (Heatstroke)
5.	Intracranial Hypertension

Experts

1.	Lessell, S: 1 article (01/2008)
2.	Kocer, N: 1 article (01/2008)
3.	Islak, C: 1 article (01/2008)
4.	Li, Gordon: 1 article (01/2008)
5.	Ozer, H: 1 article (01/2008)
6.	Albayram, S: 1 article (01/2008)
7.	Kilic, F: 1 article (01/2008)
8.	Lin, Shih-Chun: 1 article (01/2008)
9.	Kurbanyan, K: 1 article (01/2008)
10.	Baghaki, S: 1 article (01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intracranial Hypotension:

1.	Prednisolone (Predate)FDA LinkGeneric 06/01/2006 - "We concluded that oral prednisolone was effective in a case of intracranial hypotension." 06/01/2006 - "Case of intracranial hypotension responsive to oral prednisolone]" Order ALL the reference details at left...
2.	GadoliniumIBA 01/01/1998 - "In addition, gadolinium-enhanced magnetic resonance imaging study performed later supported the diagnosis of spontaneous intracranial hypotension" 12/01/2002 - "Delayed gadolinium enhancement in epidural space of the cervicothoracic spine in a patient with spontaneous intracranial hypotension." 05/01/1998 - "This report offers a description of typical changes seen on gadolinium-enhanced magnetic resonance (MR) imaging of the entire spine that indicate spontaneous intracranial hypotension (SIH)" 10/01/1995 - "Intracranial hypotension is a cause of diffuse enhancement of the pachymeninx with gadolinium, which often is associated with subdural fluid collections" 03/01/1993 - "We studied a patient with spontaneous intracranial hypotension whose gadolinium-enhanced MRI revealed an extraordinary degree of dural enhancement and striking displacement of the optic chiasm, flattening of the pons, and downward displacement of the cerebellar tonsils" Order ALL the reference details at left...
3.	Glycerol (Glycerine)FDA LinkGeneric 02/01/1983 - "In order to test the hypothesis that intracranial hypotension may have an etiological role in the development of IVH in premature infants, the authors induced intracranial hypotension in the preterm rabbit by the intraperitoneal injection of glycerol" 11/01/1993 - "Acute syndrome of intracranial hypotension with cerebral coma after drinking of a glass of undiluted glycerol by a patient with gastrojejunostomy after partial gastrectomy]" 05/01/2004 - "Apparently, the heatstroke-induced arterial hypotension, intracranial hypertension, cerebral hypoperfusion, cerebral ischaemia, brain hypoxia, increased levels of striatal glutamate, glycerol, lactate/pyruvate ratio and hydroxyl radicals, and increased striatal neuronal damage score values were all attenuated significantly by the induction of hypervolaemic haemodilution in rats immediately at the onset of heatstroke" Order ALL the reference details at left...
4.	tebufenozide (Mimic)IBA 12/01/2003 - "CONCLUSIONS: Patients with spontaneous intracranial hypotension are commonly misdiagnosed, causing a significant delay in the initiation of effective treatments and exposing patients to the risks associated with treatment for disorders that mimic intracranial hypotension" 04/01/2003 - "vestibuloatactic syndrome, impairment or loss of hearing, paresis of the mimic muscles, syndrome of intracranial hypotension etc., are suggested on the basis of an analysis of results of 94 microvascular decompression operations of the trigeminal nerve root implemented in patients with trigeminal neuralgia" 02/01/2007 - "The presentation and diagnosis of the many secondary headaches that can mimic primary headache types are also discussed, including arteriovenous malformations, spontaneous intracranial hypotension, neoplasms, pseudotumor cerebri, cervical artery dissections, cerebral venous thrombosis, Chiari I malformation, and temporal arteritis" Order ALL the reference details at left...
5.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 06/01/2004 - "Treatment of spontaneous intracranial hypotension with percutaneous placement of a fibrin sealant" 11/01/2000 - "Our observation suggests that epidural patching with fibrin glue should be considered in patients with spontaneous intracranial hypotension, if epidural blood patching fails to resolve the symptoms." 11/01/2000 - "We report a case of spontaneous intracranial hypotension due to a cerebrospinal fluid leak at the C2 level, which was successfully treated by epidural fibrin glue patching" 11/01/2000 - "Spontaneous intracranial hypotension successfully treated by epidural patching with fibrin glue." 11/01/2000 - "Although successful treatment of postdural puncture headache and persistent leak after intrathecal catheterization by epidural patching with fibrin glue has been reported, fibrin glue has not been previously applied in spontaneous intracranial hypotension" Order ALL the reference details at left...
6.	SteroidsIBA 03/01/2006 - "METHODS: Twelve consecutive patients with clinical symptoms and testing results compatible with a diagnosis of idiopathic intracranial hypotension (IIH), but no identifiable site of cerebrospinal fluid (CSF) leakage, were treated with a cervicothoracic or lumbar epidural "blood patch" (EBP) or orally administered steroids" 12/01/2005 - "Intracranial hypotension following repeated epidural injections of steroids." Order ALL the reference details at left...
7.	Sodium Chloride (Saline Solution)FDA LinkGeneric 10/01/2006 - "Diagnosis of intracranial hypotension syndrome by a bolus or continuous epidural injection of normal saline solution]" 09/01/2003 - "Intravenous infusion of hypertonic (3%) saline solution either "0" time before the start of heat exposure or right after the onset of heatstroke significantly attenuated the heatstroke-induced arterial hypotension, intracranial hypertension, decreased cerebral perfusion, and cerebral ischemia and damage and resulted in prolongation of survival time" Order ALL the reference details at left...
8.	OxygenIBA 01/01/1968 - "Therapeutic oxygen encephalography for a posttraumatic, chronic intracranial hypotension syndrome]" 08/13/2007 - "When the untreated rats underwent heat stress, their survival time values were found to be 20-24 min. Resuscitation with hyperbaric oxygen increased the survival time to new values of 152-176 min. All untreated heatstroke rats displayed cerebrovascular dysfunction (evidenced by hypotension, intracranial hypertension, and cerebral hypoperfusion, hypoxia, and ischemia), hypercoagulable state (evidenced by increased levels of activated partial thromboplastin time, prothrombin time, and D-dimer, but decreased values of platelet count and protein C in plasma), and tissue ischemia/injury (evidenced by increased levels of creatinine, serum urea nitrogen, aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase in plasma, and dihydrobenzoic acid, lipid peroxidation, and oxidized-form glutathione/reduced-form of glutathione ratio in hypothalamus)" Order ALL the reference details at left...
9.	Dopamine (Intropin)FDA LinkGeneric 01/01/1996 - "The survival time of the heatstroke rats which received normal saline (single injection or continuous perfusion) was about 17 min. The heatstroke-induced ischemic damage to striatal neurons was due to systemic arterial hypotension, intracranial hypertension, decreased cerebral perfusion, and striatal dopamine (DA) accumulation (275%)" 08/01/1995 - "However, when the striatal dopamine system was destroyed by 6-hydroxydopamine, the heatstroke-induced arterial hypotension, intracranial hypertension, ischemic damage to the striatum, and elevated striatal dopamine release were reduced" Order ALL the reference details at left...
10.	Colloids (Colloid)IBA 07/01/2006 - "TCH might be the first sign of subarachnoid haemorrhage, unruptured intracranial aneurysm, cerebral venous sinus thrombosis, cervical artery dissection, acute hypertensive crisis, spontaneous intracranial hypotension, ischaemic stroke, retroclival haematoma, pituitary apoplexy, third ventricle colloid cyst, and intracranial infection" 03/01/2007 - "Recognition and accurate diagnosis of this headache are important because it can be caused by various serious underlying brain disorders such as subarachnoid hemorrhage, intracranial hematoma, cerebral venous sinus thrombosis, cervical artery dissection, ischemic stroke, pituitary apoplexy, acute arterial hypertension, spontaneous intracranial hypotension, third ventricle colloid cyst, and intracranial infections" Order ALL the reference details at left...

Therapies and Procedures

1.	Aftercare (After-Treatment) 02/01/1994 - "After treatment of spontaneous intracranial hypotension, these findings improved or resolved" 09/01/2001 - "Magnetic resonance imaging findings before and after treatment of spontaneous intracranial hypotension." 09/04/1999 - "Seven patients with intracranial hypotension were reassessed after treatment with epidural blood patch" 07/01/2007 - "From low to high: late-onset intracranial hypertension after treatment of spontaneous intracranial hypotension." 07/01/2006 - "Rebound intracranial hypertension after treatment of spontaneous intracranial hypotension." Order ALL the reference details at left...
2.	Induced Hyperthermia (Thermotherapy) 05/01/2003 - "3. Magnolol (20 or 40 mg/kg, i.v.) significantly attenuated the heatstroke-induced hyperthermia, arterial hypotension, intracranial hypertension, cerebral ischaemia and neuronal damage and increased free radical formation and lipid peroxidation in the brain" 05/01/2004 - "Delaying onset of aminoguanidine administration (i.e., 0 or 30 min after the start of heat exposure) reduced the preventive efficiency on heatstroke-induced hyperthermia, arterial hypotension, intracranial hypertension, cerebral ischemia, and increased iNOS-dependent NO formation in brain" 05/01/2004 - "Aminoguanidine (30 micromol/kg, i.v.; 30 min before the start of heat exposure) pretreatment significantly attenuated the heatstroke-induced hyperthermia, arterial hypotension, intracranial hypertension, cerebral ischemia and neuronal damage, and increased iNOS-dependent NO formation in the brain" 04/01/2006 - "Furthermore, the heatstroke-induced hyperthermia, arterial hypotension, intracranial hypertension, and cerebral hypoperfusion, hypoxia, and ischemia were significantly attenuated by premarin therapy in ovariectomized rats" 12/01/2005 - "The heatstroke-induced hyperthermia, arterial hypotension, intracranial hypertension, cerebral hypoperfusion and hypoxia, and increased levels of cellular ischemia and damage markers in striatum were all significantly attenuated by prior administration of CTAP" Order ALL the reference details at left...
3.	Craniotomy 01/01/2003 - "RESULTS: Two patients developed transient postoperative neurological complications as a result of intracranial hypotension that resolved after epidural blood patching, with a reexploration craniotomy to drain an epidural collection performed in one patient" 12/01/2003 - "Diagnostic or therapeutic procedures for disorders that mimicked spontaneous intracranial hypotension included cerebral arteriography in 2 patients, craniotomies for Chiari malformation in 2 patients, craniotomy for evacuation of subdural hematomas in 1 patient, and brain biopsy in 1 patient" 11/01/1994 - "Unexplained bradycardia during craniotomy closure: the role of intracranial hypotension." 02/01/1993 - "Unexplained bradycardia during craniotomy closure: the role of intracranial hypotension." 06/01/1967 - "Syndrome of intracranial hypotension associated with osteoclastic bifrontal craniotomy, presentation of a case]" Order ALL the reference details at left...
4.	Chiropractic Manipulation 10/01/2006 - "We report a case of intracranial hypotension caused by chiropractic manipulation which, in contrast to previously reported cases, documents the location of the cerebrospinal fluid leak by radionuclide cisternography" 06/15/2005 - "CONCLUSIONS: From this case, we can understand the etiology of intracranial hypotension and consider the complication of chiropractic manipulation." 06/15/2005 - "This is the first case of spontaneous intracranial hypotension in which spinal chiropractic manipulation coincided with the development of symptoms and in which a CSF collection in the upper cervical and thoracic spine was demonstrated radiographically in Korea" 06/15/2005 - "OBJECTIVES: We report a case of intracranial hypotension ensuing after a spinal chiropractic manipulation leading to cerebrospinal fluid (CSF) isodense effusion in the upper cervical and thoracic spine" 06/15/2005 - "Intracranial hypotension induced by cervical spine chiropractic manipulation." Order ALL the reference details at left...
5.	Diskectomy (Discectomy) 03/01/1999 - "We describe a patient with the history of an uncomplicated lumbar discectomy at the level L4-5 and the typical clinical symptoms of intracranial hypotension" 12/01/2001 - "Intracranial hypotension syndrome due to duropleural fistula after thoracic diskectomy." 06/01/2000 - "We report a unique situation in which a patient developed severe postural headache typical of intracranial hypotension, which was complicated by bilateral subdural hematomas, immediately following a routine lumbar diskectomy; the headache resolved spontaneously" Order ALL the reference details at left...

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