Hot Flashes

10/01/2018 - "Although estrogen remains the most effective medication to reduce hot flashes, its potential harmful effects have led investigators to examine other treatments for hot flashes, and many women seek alternative forms of relief. "
09/01/2008 - "Estrogen is the most effective treatment for management of hot flashes and night sweats. "
01/01/2007 - "Estrogen reliably reduces the severity of hot flashes and remain the single most effective treatment. "
01/01/2006 - "Short-term estrogen remains the most effective treatment for hot flashes, but because of safety concerns many women are reluctant to use this treatment. "
01/01/2015 - "There is strong evidence to conclude that low-dose transdermal estrogen at any dose is more effective than placebo in decreasing the daily number of moderate to severe hot flashes."

02/01/2009 - "Women assigned to gabapentin reported a significantly greater percent reduction in both the frequency of hot flashes (WMD = 23.72 [95% CI, 16.46-30.97]; P < 0.001) and the composite score (WMD = 27.26 [95% CI, 21.24-33.29]; P < 0.001), with significant between-study heterogeneity (I(2) = 97.8% and 95.6%, respectively). "
08/09/2010 - "Gabapentin is another nonhormonal agent that is effective in reducing hot flashes. "
01/01/2009 - "Although the studies were few, all showed gabapentin to be safe and effective in the treatment of hot flashes. "
04/01/2013 - "Gabapentin shows moderate efficacy for the long-term treatment of hot flashes in a dose-dependent manner. "
12/19/2005 - "Anecdotal observations also suggested that gabapentin was helpful for alleviating hot flashes. "

04/01/2016 - "Venlafaxine 75 mg daily improved hot flashes without additional side effects from higher dosing. "
01/01/2007 - "Venlafaxine resulted in modest decreases in hot flashes, but only hot flash interference improved differentially at the higher dose. "
05/01/2003 - "Previous studies have defined that venlafaxine, an anti-depressant, is an effective treatment for such hot flashes. "
11/01/2003 - "Venlafaxine is an effective nonhormonal alternative for relief from uncontrolled hot flashes."
01/01/2002 - "The data from this study provides evidence that venlafaxine has intermediate term efficacy and good tolerability as a treatment for hot flashes. "

05/01/2006 - "Is paroxetine an effective treatment for hot flashes?"
10/01/2005 - "Paroxetine is an effective treatment for hot flashes: results from a prospective randomized clinical trial."
01/01/2023 - "Relevant databases were searched to identify randomized clinical trials examining the efficacy of paroxetine to treat hot flashes. "
01/01/2018 - "The aim of this study was to investigate and compare the effectiveness of stellate ganglion block (SGB) with that of paroxetine, which was approved by the US Food and Drug Administration (FDA) as a medicine for the treatment of hot flashes and ensuing sleep disturbance. "
12/01/2016 - "This is the first randomized placebo-controlled study in gynecological cancer survivors that demonstrates that paroxetine significantly reduces hot flashes in weekly frequency and severity and the number of nighttime awakenings attributed to vasomotor symptoms, increasing sleep duration."

01/01/2023 - "Materials and Methods: We used a Bayesian network (BN) to examine the relationship between multiple factors known to influence sleep and depression in midlife women, including hormone concentrations, hot flashes, and menopause status among participants of the longitudinal Midlife Women's Health Study. "
01/01/2019 - "The objective of this study is to determine hormone measurement summaries that best explain the incidence of hot flashes in midlife women. "
01/01/2019 - "Although based on an iterative process, the resulting exhibit content reflects an estimated 500+ scientific studies, including those referenced in The North American Menopause Society position statements on hormone and nonhormone management of hot flashes. "
10/01/2015 - "The aim of this study was to examine the associations of demographic characteristics, health behaviors, and hormone concentrations with the experience of any, current, more severe, and more frequent midlife hot flashes. "
09/01/2014 - "This study aims to estimate the risk of hot flashes relative to natural menopause and to evaluate the associations of hormone levels, behavioral variables, and demographic variables with the risk of hot flashes after menopause. "

07/01/2012 - "Soy isoflavone supplements, derived by extraction or chemical synthesis, are significantly more effective than placebo in reducing the frequency and severity of hot flashes. "
04/01/2015 - "This study aimed to quantitate the efficacy of soy isoflavones in the treatment of menopausal hot flashes. "
07/01/2000 - "Although some data seem to support the efficacy of isoflavones in reducing the incidence and severity of hot flashes, many studies have not found any difference between the isoflavone recipients and the controls. "
04/01/2015 - "Quantitative efficacy of soy isoflavones on menopausal hot flashes."
07/01/2012 - "This analysis was conducted to determine the efficacy of extracted or synthesized soybean isoflavones in the alleviation of hot flashes in perimenopausal and postmenopausal women. "

01/01/2009 - "SLC is effective in alleviating tamoxifen-induced hot flashes and improving the condition of sleep."
01/01/2013 - "Compared with tamoxifen, there is a reduced incidence of endometrial changes, thromboembolic events, and hot flashes. "
04/01/2008 - "At study entry, 864 (56%) of these women were taking tamoxifen, and hot flashes were reported by 674 (78%). "
01/01/2019 - "Patient-reported outcomes were not different between arms except for a slight increase in frequency of daily hot flashes with tamoxifen (P = .02). "
10/01/2018 - "Tamoxifen use is often limited by adverse effects including severe hot flashes. "

01/01/2009 - "These data and subsequent study conclusions are evaluated and discussed in the context of other published trial data regarding the use of newer antidepressants for treating hot flashes. "
01/01/2009 - "Raw data from these two randomized, placebo-controlled trials evaluating second-generation antidepressants for hot flashes were obtained. "
01/01/2009 - "These two studies have repeatedly been put forward as evidence that newer antidepressants are not definitively proven to reduce hot flashes. "
12/19/2005 - "All 3 of these clinical trials demonstrated statistically significant reductions in hot flashes with these newer antidepressants compared with placebo. "
12/16/2000 - "Confirmation of the results of this 4-week study awaits the completion of three ongoing randomised studies to assess the effects of other related antidepressants for the treatment of hot flashes."

01/01/2004 - "Oral and transdermal formulations of clonidine are moderately effective in reducing hot flashes. "
03/01/1987 - "A randomized prospective double-blind study was performed to evaluate the efficacy of a transdermal therapeutic system delivering clonidine in the treatment of menopausal hot flashes. "
07/01/2001 - "Clonidine reduces central sympathetic activation, widens the thermoneutral zone, and ameliorates hot flashes. "
11/01/1982 - "The effectiveness of clonidine in suppressing the occurrence of postmenopausal hot flashes was examined using a dose-response study design and objective recordings of hot flashes. "
05/01/2005 - "This narrowing may be due to elevated central noradrenergic activation, a contention supported by observations that clonidine and some relaxation procedures ameliorate hot flashes. "

01/01/2021 - "It was found that the baseline number of hot flashes was an important factor affecting the efficacy of acupuncture and sham acupuncture. "
07/01/2009 - "In the sham acupuncture group a significant reduction of 25% in hot flashes at day was seen during treatment, but was reversed during the following 12 weeks. "
01/01/2007 - "The results of this study suggest that the used medical acupuncture was not any more effective for reducing hot flashes than was the chosen sham acupuncture."
10/27/2023 - "We will be able to measure the effectiveness of acupuncture for patients with PCa suffering from ADT-induced hot flashes and whether acupuncture is superior to sham acupuncture and usual care. "
01/01/2021 - "This study aimed to compare the efficacy of acupuncture to that of sham acupuncture, placebo pills, and nonhormonal drugs to provide the necessary quantitative information for establishing medication guidelines for menopausal hot flashes. "

02/11/2022 - "The triple combination in the optimal doses pertains to efficacy against all three mechanisms of action, serves as a multitarget plant-based therapy and could serve as a novel strategy for the alleviation of hot flashes in postmenopausal women."
11/01/1985 - "In addition to a marked improvement in the remission rate and survival, combination therapy maintains a good quality of life, hot flashes and a decrease or loss of libido being the only side-effects."
08/01/2003 - "Although more definitive research is necessary, several natural therapies show promise in treating hot flashes without the risks associated with conventional therapies. "
03/01/2012 - "While hormonal therapy of hot flashes has been shown to be effective, multiple non-hormonal medications and treatment methods have also been developed. "
08/01/2010 - "Black cohosh appears to be effective therapy for relieving menopausal symptoms, primarily hot flashes, in early menopause. "

01/01/2022 - "This report presents a patient with very low ovarian reserve, with medical problems that preclude her from taking hormone replacement therapy, who presented for fertility treatment with PRP and then accidentally reported significant improvement of menopausal symptoms including her hot flashes for 14 weeks following PRP intra-ovarian injection. "
03/01/2003 - "Hormone replacement therapy successfully relieved or substantially decreased the hot flashes in all 8 patients treated. "
01/01/2015 - "Currently, hormone replacement therapy (HRT) is the only US Food and Drug Administration-approved treatment for hot flashes, resulting in clinical improvement in 80%-90% of symptomatic women. "
06/01/2015 - "At present, there is growing demand for alternative, or additional, treatments to hormone replacement therapy for menopause-related hot flashes (HF). "
09/01/2012 - "According to the results of this clinical trial, BRN-01 may be considered a new therapeutic option with a safe profile for hot flashes in menopausal women who do not want or are not able to take hormone replacement therapy or other recognized treatments for this indication. "

12/01/2016 - "One systematic review suggests modest improvement in hot flashes and vaginal dryness with soy products, and small studies suggest that clinical hypnosis significantly reduces hot flashes. "
07/01/2004 - "We conclude that hypnosis is a mind-body intervention that may be of significant benefit in treatment of hot flashes and other benefits may include reduced anxiety and improved sleep. "
01/01/2013 - "Based on the authors' previous research, the present study was developed to evaluate the feasibility of a guided self-hypnosis intervention for hot flashes. "
10/11/2011 - "The present study will compare hypnosis to a structured-attention control in reducing hot flashes (perceived and physiologically monitored) in post-menopausal women in a randomized clinical trial. "
10/11/2011 - "Hypnosis for hot flashes among postmenopausal women study: a study protocol of an ongoing randomized clinical trial."

01/01/2013 - "This article discusses the superior efficacy of the newer nonhormonal prescriptions for the treatment of hot flashes when compared with estrogen replacement therapy, and provides some recommendations regarding use of them in peri- and postmenopausal women."
11/01/2000 - "A few studies reveal a minimal effect of soy on hot flashes, with soy reducing hot flashes 45% and placebo causing a 30% reduction compared with an approximate 70% reduction in hot flashes with estrogen replacement therapy. "
06/01/2014 - "Concerned about the safety of conventional estrogen replacement therapy, women are using botanical dietary supplements as alternatives for the management of menopausal symptoms such as hot flashes. "
12/01/2008 - "Estrogen replacement therapy alleviates the number and severity of hot flashes but is contraindicated in such cases. "
07/01/1997 - "Knowledge of the nature of these disease processes is necessary for quick recognition of patients with hot flashes who do not respond to estrogen replacement treatment, and to facilitate the proper evaluation of atypical patients."

08/01/2010 - "Hot flashes were significantly improved after acupuncture treatment in both of the patients, and the effects persisted through the final observation period (hot flash scores decreased from 57 to 33 and 22 at 1 and 11 months from baseline in patient 1, and from 14 to 6 and zero at 1 and 7 months from baseline in patient 2). "
04/20/2007 - "Standardized, individually tailored acupuncture treatment was associated with significantly greater decrease in the severity, but not the frequency, of hot flashes, in symptomatic postmenopausal women when compared to placebo acupuncture of equal duration. "
01/01/2021 - "Randomized clinical studies on acupuncture therapy for the treatment of hot flashes in menopausal women were identified. "
05/01/2011 - "The purpose of this study was to examine the prevalence of depressive symptoms, as measured by the Beck Depression Inventory; the effect of acupuncture therapy for menopausal hot flashes on depressive symptoms; and the associations between depressive symptoms and hot flashes, sleep disturbances, and self-reported health. "
03/01/2010 - "The previously published Acupuncture on Hot Flashes Among Menopausal Women study compared the effectiveness of individualized acupuncture treatment plus self-care versus self-care alone on hot flashes and health-related quality of life in postmenopausal women. "