Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy)

A congenital cardiomyopathy that is characterized by infiltration of adipose and fibrous tissue into the RIGHT VENTRICLE wall and loss of myocardial cells. Primary injuries usually are at the free wall of right ventricular and right atria resulting in ventricular and supraventricular arrhythmias.
Also Known As:
Arrhythmogenic Right Ventricular Cardiomyopathy; Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia; Arrhythmogenic Right Ventricular Cardiomyopathy Dysplasia; Right Ventricular Dysplasia, Arrhythmogenic; Ventricular Dysplasia, Right, Arrhythmogenic
Networked: 339 relevant articles (4 outcomes, 22 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Ventricular Tachycardia
2. Syncope (Fainting)
3. Cardiomyopathies (Cardiomyopathy)
4. Brugada Syndrome
5. Long QT Syndrome


1. Basso, Cristina: 18 articles (04/2015 - 11/2002)
2. Thiene, Gaetano: 17 articles (04/2015 - 11/2002)
3. Calkins, Hugh: 16 articles (08/2014 - 05/2004)
4. McKenna, William J: 14 articles (08/2012 - 03/2004)
5. Bauce, Barbara: 12 articles (04/2015 - 11/2002)
6. Nava, Andrea: 12 articles (12/2013 - 11/2002)
7. Rampazzo, Alessandra: 11 articles (01/2015 - 11/2002)
8. Saffitz, Jeffrey E: 10 articles (11/2014 - 05/2004)
9. Asimaki, Angeliki: 10 articles (11/2014 - 09/2006)
10. Wichter, Thomas: 10 articles (02/2011 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Arrhythmogenic Right Ventricular Dysplasia:
1. Anti-Arrhythmia AgentsIBA
2. carvedilol (Coreg)FDA LinkGeneric
3. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
4. CatecholaminesIBA
5. gamma Catenin (Plakoglobin)IBA
6. Desmoplakins (Desmoplakin)IBA
7. Uhl anomalyIBA
8. Polymorphic catecholergic ventricular tachycardiaIBA
01/01/2014 - "Based on the clinical characteristics of our case, presenting some overlapping clinical features common to both the diseases, the discussion will be focused on Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia (ARVC/D). "
04/01/2008 - "Several disease-linked mutations of RyR have been reported in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) or arrhythmogenic right ventricular cardiomyopathy type 2 (ARVC2). "
09/01/2005 - "More recently, a considerable number of disease-linked mutations in the RyR have been reported in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) or arrhythmogenic right ventricular dysplasia type 2. An analysis of the disposition of these mutation sites within well-defined domains of the RyR polypeptide chain has led to the new concept that interdomain interactions among these domains play a critical role in channel regulation, and an altered domain interaction causes channel dysfunction in the failing heart. "
07/01/2005 - "The observation of both arrhythmogenic right ventricular cardiomyopathy type 2 and catecholaminergic polymorphic ventricular tachycardia in the same family suggests that the two entities might correspond to different degrees of phenotypic expression of the same disease. "
06/01/2013 - "We studied the prevalence, clinical phenotypes, and risk of SCD presented by ten rare mutations previously associated with arrhythmogenic right ventricular cardiomyopathy, long QT syndrome, or catecholaminergic polymorphic ventricular tachycardia. "
9. Paroxysmal ventricular fibrillationIBA
10. SodiumIBA

Therapies and Procedures

1. Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
2. Defibrillators (Defibrillator)
3. Heart Transplantation (Grafting, Heart)
4. Transplants (Transplant)
5. Homologous Transplantation (Allograft)