|1.||Nelson, Celeste: 3 articles (01/2015 - 01/2015)|
|2.||Xie, Zhihui: 3 articles (01/2015 - 01/2015)|
|3.||Druey, Kirk M: 3 articles (01/2015 - 01/2015)|
|4.||Long, Lauren M: 3 articles (01/2015 - 01/2015)|
|5.||Sek, Albert C: 2 articles (01/2015 - 01/2015)|
|6.||Terai, Kaoru: 2 articles (01/2015 - 01/2015)|
|7.||Dudek, Arkadiusz Z: 2 articles (01/2015 - 01/2015)|
|8.||Shin, Jae Il: 2 articles (01/2012 - 02/2009)|
|9.||Yu, Alice L: 2 articles (09/2010 - 01/2009)|
|10.||Matthay, Katherine K: 2 articles (09/2010 - 01/2009)|
|1.||Intravenous Immunoglobulins (IVIG)FDA Link
07/01/2008 - "Intravenous immunoglobulins were effective against systemic capillary leak syndrome symptoms in three patients, but their exact mechanism remains unknown. "
07/01/2008 - "The objective of this study was to report the dramatic improvement of patients with systemic capillary leak syndrome obtained with high-dose intravenous immunoglobulins. "
04/22/2014 - "[Use of intravenous immunoglobulins in a patient with systemic capillary leak syndrome]."
04/01/2012 - "Successful treatment of systemic capillary leak syndrome with intravenous immunoglobulins."
01/01/2011 - "High-dose intravenous immunoglobulins: a promising therapeutic approach for idiopathic systemic capillary leak syndrome."
|2.||Nitric Oxide (Nitrogen Monoxide)FDA Link
04/01/2000 - "The common mechanism for IL-2-induced multiorgan dysfunction appears to be a capillary leak syndrome directly mediated by local production of nitric oxide by cells of the monocyte-macrophage lineage. "
01/01/1997 - "Previously, we showed that nitric oxide (NO) plays a major role in the pathogenesis of IL-2-induced capillary leak syndrome in healthy or mammary adenocarcinoma-bearing C3H/HeJ mice. "
11/01/1995 - "NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin-2-induced capillary leak syndrome in healthy mice."
03/01/1998 - "Role of nitric oxide in IL-2 therapy-induced capillary leak syndrome."
10/01/2001 - "Clinical application of interleukin (IL)-2-based immunotherapy of cancer has been limited by a major side-effect known as 'capillary leak syndrome', resulting from nitric oxide (NO) overproduction. "
|3.||Adrenal Cortex Hormones (Corticosteroids)IBA
10/01/1999 - "Treatment with corticosteroids should be considered for prevention of attacks in the systemic capillary leak syndrome."
07/01/2000 - "This case suggests that corticoids may be useful in the management of neoplasm induced capillary leak syndrome."
10/01/2009 - "Cure of gemcitabine-induced systemic capillary leak syndrome without corticosteroids."
01/01/2002 - "Denileukin diftitox is associated with capillary leak syndrome in 20 to 30% of patients, which may be ameliorated by hydration and corticosteroids. "
|4.||NG-Nitroarginine Methyl Ester (L-NAME)IBA
|5.||Ofloxacin (Levofloxacin)FDA LinkGeneric
|6.||Peptide Hydrolases (Proteases)IBA
07/01/1996 - "The severe side effects usually associated with classical lymphokine-activated killer therapy in association with high doses of interleukin 2, such as "capillary leak syndrome," were absent in this study. "
09/01/2008 - "Capillary leak syndrome has been associated with IL-2 therapy and many of its cardiac and noncardiac toxicities. "
09/01/2001 - "The main adverse effect of IL-2 is capillary leak syndrome caused by increased capillary permeability and extravasation of fluid. "
06/01/1999 - "Treatment with intravenous recombinant human interleukin-2 (rh IL-2) is frequently accompanied by the capillary leak syndrome and disturbances of the coagulation system. "
03/01/1998 - "We tested the hypothesis that 'capillary leak syndrome' following systemic interleukin-2 (IL-2) therapy resulted from a cascade of events leading to the induction of NO which, directly or indirectly, injured capillaries and caused fluid leakage. "
|8.||Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/01/2005 - "The study purpose was to report the first case of granulocyte colony-stimulating factor (G-CSF)-induced capillary leak syndrome (CLS) in which serial extravascular lung water (EVLW) measurements were performed and to compare this case with previously reported cases. "
04/01/2012 - "[Capillary leak syndrome (CLS) induced by G-CSF: 3 cases report and literature review]."
01/01/2011 - "Systemic capillary leak syndrome caused by granulocyte colony-stimulating factor."
01/01/2011 - "A case of idiopathic systemic capillary leak syndrome with high serum levels of G-CSF on exacerbation."
02/01/2005 - "Granulocyte colony-stimulating factor-induced capillary leak syndrome confirmed by extravascular lung water measurements."
03/01/2009 - "Systemic administration of gemcitabine was accomplished in 93%; however, 1 patient died of serious capillary leak syndrome. "
12/01/2007 - "Rare cases of gemcitabine-associated systemic capillary leak syndrome have been reported. "
02/01/2006 - "Gemcitabine-induced chronic systemic capillary leak syndrome: a life-threatening disease."
11/01/2001 - "Gemcitabine-induced systemic capillary leak syndrome."
12/01/2007 - "Here, we present two cases of capillary-leak syndrome in patients with pancreatic cancer treated with gemcitabine."
01/01/2015 - "A prospective, randomized trial may be necessary to fully assess the benefits of intravenous immunoglobulin for systemic capillary leak syndrome and to determine the optimal dosage and duration of therapy."
01/01/2015 - "Intravenous immunoglobulin prophylaxis is associated with a dramatic reduction in the occurrence of systemic capillary leak syndrome attacks in most patients, with minimal side effects. "
01/01/2015 - "We evaluated intravenous immunoglobulin prophylactic therapy in a cohort of 29 patients with systemic capillary leak syndrome in a longitudinal follow-up study. "
03/01/2014 - "Intravenous immunoglobulin in systemic capillary leak syndrome: a case report and review of literature."
06/01/2010 - "Immunoglobulins for treatment of systemic capillary leak syndrome."
|1.||Extracorporeal Membrane Oxygenation (ECMO)
03/01/1977 - "The best results have been obtained in newborn cases and the adult capillary leak syndromes; the major problem has been progression to fibrosis despite ECMO support. "
11/01/2000 - "An inflammatory response and a capillary leak syndrome frequently develop during the treatment of neonatal respiratory failure by extracorporeal membrane oxygenation (ECMO). "
06/01/1996 - "Progressive hypotension as a result of capillary leak syndrome precluded further ECMO support in the other 3 patients. "
|2.||Cardiopulmonary Bypass (Heart-Lung Bypass)
08/13/2005 - "Capillary leak syndrome in children with C4A-deficiency undergoing cardiac surgery with cardiopulmonary bypass: a double-blind, randomised controlled study."
08/01/2013 - "As an inflammatory reaction after cardiac surgery involving cardiopulmonary bypass (CPB), capillary leak syndrome (CLS) is associated with increased morbidity, especially in newborns and infants. "
08/01/2013 - "Early prediction of capillary leak syndrome in infants after cardiopulmonary bypass."
09/01/2010 - "Its low priming volume and blood contact surface may significantly reduce known complications related to cardiopulmonary bypass in neonates (e.g., inflammatory reaction and capillary leak syndrome)."
08/13/2005 - "Capillary leak syndrome is a life-threatening complication after cardiopulmonary bypass (CPB), with an incidence of about 4-37% in children worldwide. "
06/01/2014 - "Systemic capillary leak syndrome under general anesthesia: a case report."
01/01/2008 - "Acute pulmonary capillary leak syndrome during elective surgery under general anesthesia."
11/01/2015 - "The aim of this study was to review the relative risks, benefits, and anesthetic considerations of neuraxial, regional, and general anesthesia in a patient with known systemic capillary leak syndrome (SCLS) who presents for elective total knee replacement. "
|4.||Knee Replacement Arthroplasty (Total Knee Replacement)