HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

HIV Integrase Inhibitors

Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA.

Also Known As:

Inhibitors, HIV Integrase; Integrase Inhibitors, HIV

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Anti-Infective Agents: 8032
      - Antiviral Agents: 47706
        Anti-Retroviral Agents: 656
        Anti-HIV Agents: 514
        HIV Integrase Inhibitors: 12
  - Molecular Mechanisms of Pharmacological Action: 24
    - Enzyme Inhibitors: 1659
      - Integrase Inhibitors: 297
        HIV Integrase Inhibitors: 12

Experts

1.	Abdel-Magid, Ahmed F: 2 articles (01/2017 - 02/2014)
2.	Atlan, Michael: 1 article (01/2022)
3.	Auclair, Martine: 1 article (01/2022)
4.	Barrail-Tran, Aurélie: 1 article (01/2022)
5.	Beaupère, Carine: 1 article (01/2022)
6.	Bourgeois, Christine: 1 article (01/2022)
7.	Béréziat, Véronique: 1 article (01/2022)
8.	Capeau, Jacqueline: 1 article (01/2022)
9.	Desjardins, Delphine: 1 article (01/2022)
10.	Foresti, Roberta: 1 article (01/2022)

Related Diseases

1.	Infections 07/01/2014 - "This study showed that the HIV integrase inhibitors also block herpesviral infection, raising the important potential of a new class of anti-herpes drugs and the prospect of drugs that combat both HIV and the herpesviruses." 01/01/2011 - "The ten stories belonging to this fifth part are dealing with (i) aurintricarboxylic acid; (ii) alkenyldiarylmethanes; (iii) human immunodeficiency virus (HIV) integrase inhibitors; (iv) lens epithelium-derived growth factor as a potential target for HIV proviral DNA integration; (v) the status presens of neuraminidase inhibitors NAIs in the control of influenza virus infections; (vi) the status presens on respiratory syncytial virus inhibitors; (vii) tricyclic (1,N-2-ethenoguanine)-based acyclovir and ganciclovir derivatives; (viii) glycopeptide antibiotics as antivirals targeted at viral entry; (ix) the potential (off-label) use of cidofovir in the treatment of polyoma (JC and BK) virus infections; and (x) finally, thymidine phosphorylase as a target for both antiviral and anticancer agents."
2.	HIV Infections (HIV Infection) 01/12/2017 - "Treatment of HIV Infections with HIV Integrase Inhibitors." 02/13/2014 - "HIV Integrase Inhibitors for Treatment of HIV Infections and AIDS." 02/01/2010 - "GSK-1349572 (S/GSK-1349572), under development by ViiV Healthcare and Shionogi & Co Ltd, is the lead from a series of HIV integrase inhibitors, for the potential oral treatment of HIV infection. " 02/01/2010 - "Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection."
3.	Acquired Immunodeficiency Syndrome (AIDS) 07/01/2007 - "HIV integrase inhibitors as therapeutic agents in AIDS." 01/01/2001 - "[HIV integrase inhibitors: a promising development in AIDS research]." 02/13/2014 - "HIV Integrase Inhibitors for Treatment of HIV Infections and AIDS."
4.	Coinfection 11/24/2009 - "In the following review we want to focus on the new class of HIV integrase inhibitors and discuss present data with regard to special issues of HIV and HCV co-infection."
5.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 05/26/2010 - "Dimeric naphthoquinones (BiQ) were originally synthesized as a new class of HIV integrase inhibitors but have shown integrase-independent cytotoxicity in acute lymphoblastic leukemia cell lines suggesting their use as potential anti-neoplastic agents. "

Related Drugs and Biologics

1.	Integrases
2.	dolutegravir
3.	Ganciclovir (Cytovene)
4.	Thymidine Phosphorylase
5.	Neuraminidase (Sialidase)
6.	Naphthoquinones
7.	Glycopeptides
8.	Fumarates
9.	DNA (Deoxyribonucleic Acid)
10.	Aurintricarboxylic Acid

Related Therapies and Procedures

1.	Off-Label Use