|1.||Nair, Vasu: 3 articles (08/2014 - 05/2002)|
|2.||Neamati, N: 2 articles (07/2001 - 06/2001)|
|3.||Pommier, Y: 2 articles (07/2001 - 06/2001)|
|4.||Roberts, Victoria A: 1 article (09/2015)|
|5.||Bharti, Sanjay Kumar: 1 article (08/2015)|
|6.||Mahapatra, Debarshi Kar: 1 article (08/2015)|
|7.||Asati, Vivek: 1 article (08/2015)|
|8.||Hafey, Michael: 1 article (02/2015)|
|9.||Walji, Abbas M: 1 article (02/2015)|
|10.||Wu, Yunhui: 1 article (02/2015)|
01/14/2015 - "We investigated whether monthly injections of a long-acting formulation of the HIV integrase inhibitor GSK1265744 (GSK744 LA) prevented simian/human immunodeficiency virus (SHIV) infection by vaginal challenge in macaques. "
09/25/2008 - "The good profile of Raltegravir has enabled its progression toward the end of phase III clinical trials for the treatment of HIV-1 infection and culminated with the FDA approval as the first HIV-integrase inhibitor for the treatment of HIV-1 infection."
04/01/2013 - "Importantly, one HIV integrase strand transfer inhibitor, raltegravir (RAL), potently inhibited single-round infection as well as cell-free and cell-to-cell SRV-4 transmission. "
07/23/2002 - "To improve the existing combination therapies of infection with the human immunodeficiency virus (HIV) and to cope with virus strains that are resistant to multiple drugs, we initiated a search for effective inhibitors of HIV integrase, the enzyme responsible for inserting the viral cDNA into the host cell chromosome. "
09/25/2008 - "Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection."
|2.||Acquired Immunodeficiency Syndrome (AIDS)
03/01/2009 - "HIV integrase has emerged as a promising target for discovery of agents against the acquired immunodeficiency syndrome (AIDS) pandemic. "
01/01/2003 - "In spite of some effort in this area targeted at the discovery of therapeutically useful inhibitors of this viral enzyme, there are no drugs for HIV/AIDS in clinical use where the mechanism of action is inhibition of HIV integrase. "
05/01/2002 - "In spite of some effort in this area targeted at the discovery of therapeutically useful inhibitors of this viral enzyme, there are no drugs for HIV/AIDS in clinical use where the mechanism of action is inhibition of HIV integrase. "
06/04/2001 - "Discovery of novel inhibitors of HIV integrase is of considerable significance in approaches to the development of therapeutic agents against AIDS. "
07/01/2001 - "For this reason, HIV integrase (IN) has become an important target for the development of new AIDS therapeutics. "
|3.||HIV Infections (HIV Infection)
01/01/2014 - "Dolutegravir (DTG) is an HIV integrase strand transfer inhibitor approved for use in combination with other antiretrovirals for the treatment of HIV-infection in adults and adolescents. "
01/01/2014 - "Dolutegravir, an HIV integrase inhibitor for the treatment of HIV infection."
01/01/2008 - "Recent progress in the development of inhibitors of human immunodeficiency virus (HIV) integrase for the management of HIV infection."
03/01/2005 - "HIV integrase is a rational target for treating HIV infection and preventing AIDS. "
02/01/2015 - "Raltegravir is a small molecule HIV integrase strand-transfer inhibitor approved for the treatment of HIV infection with twice-daily administration. "
08/28/2015 - "Several natural and (semi) synthetic chalcones deserve the credit of being potential anti-infective candidates that inhibit various parasitic, malarial, bacterial, viral, and fungal targets like cruzain-1/2, trypanopain-Tb, trans-sialidase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), fumarate reductase, falcipain-1/2, β-hematin, topoisomerase-II, plasmepsin-II, lactate dehydrogenase, protein kinases (Pfmrk and PfPK5), and sorbitol-induced hemolysis, DEN-1 NS3, H1N1, HIV (Integrase/Protease), protein tyrosine phosphatase A/B (Ptp-A/B), FtsZ, FAS-II, lactate/isocitrate dehydrogenase, NorA efflux pump, DNA gyrase, fatty acid synthase, chitin synthase, and β-(1,3)-glucan synthase. "
|5.||Autoimmune Diseases (Autoimmune Disease)
|2.||DNA (Deoxyribonucleic Acid)
|3.||Anti-Retroviral Agents (Antiretroviral Agents)
|4.||Complementary DNA (cDNA)