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Integrases

Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
Also Known As:
Integrase
Networked: 357 relevant articles (7 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Engelman, Alan: 14 articles (04/2014 - 01/2004)
2. Hazuda, Daria J: 9 articles (10/2014 - 02/2003)
3. Calos, Michele P: 8 articles (04/2012 - 06/2003)
4. Pommier, Yves: 6 articles (01/2016 - 03/2006)
5. Marchand, Christophe: 6 articles (01/2016 - 03/2006)
6. Wainberg, Mark A: 5 articles (10/2015 - 01/2010)
7. Li, Xiang: 5 articles (04/2014 - 12/2008)
8. Ronfort, Corinne: 5 articles (12/2011 - 11/2003)
9. Moreau, Karen: 5 articles (12/2011 - 11/2003)
10. Rowley, Michael: 5 articles (03/2011 - 05/2007)

Related Diseases

1. Infection
2. HIV Infections (HIV Infection)
3. Urticaria (Hives)
4. Rheumatoid Arthritis
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. MK 0518
2. DNA (Deoxyribonucleic Acid)
3. Human immunodeficiency virus 1 reverse transcriptase
4. triphosphoric acid (triphosphate)
5. RNA-Directed DNA Polymerase (Reverse Transcriptase)
6. Glycoproteins (Glycoprotein)
7. Proteins (Proteins, Gene)
8. Viral DNA
9. Protease Inhibitors (Protease Inhibitor)
10. Enzymes

Related Therapies and Procedures

1. Highly Active Antiretroviral Therapy (HAART)
2. Therapeutics
3. Immunotherapy
4. Intramuscular Injections
5. Drug Therapy (Chemotherapy)