Artificial Pancreas

Devices for simulating the activity of the pancreas. They can be either electromechanical, consisting of a glucose sensor, computer, and insulin pump or bioartificial, consisting of isolated islets of Langerhans in an artificial membrane.

Also Known As:

Networked: 435 relevant articles (49 outcomes, 75 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Dassau, Eyal: 32 articles (10/2021 - 06/2010)
2.	Doyle, Francis J: 30 articles (01/2021 - 06/2010)
3.	Haidar, Ahmad: 20 articles (12/2021 - 03/2013)
4.	Cobelli, Claudio: 18 articles (01/2022 - 11/2010)
5.	Hovorka, Roman: 15 articles (01/2022 - 07/2009)
6.	Cinar, Ali: 14 articles (11/2019 - 01/2013)
7.	Breton, Marc D: 13 articles (01/2022 - 08/2014)
8.	Legault, Laurent: 13 articles (12/2021 - 03/2013)
9.	Renard, Eric: 13 articles (01/2019 - 11/2010)
10.	Gondhalekar, Ravi: 12 articles (05/2018 - 11/2013)

Related Diseases

1.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/01/2015 - "While the long sought-after cure for diabetes remains elusive, artificial pancreas or closed-loop systems hold the most promise for improving the burden of care in the near term for children and adolescents with type 1 diabetes." 11/01/2013 - "Recent in-hospital studies of artificial pancreas (AP) systems have shown promising results in improving glycemic control in patients with type 1 diabetes mellitus. " 10/05/2023 - "Open-source Artificial Pancreas Systems Are Safe and Effective When Supported In-clinic: Outcomes in 248 Consecutive Type 1 Diabetes Clients." 06/01/2018 - "Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis." 01/01/2021 - "Artificial pancreas system (APS) is an emerging new treatment for type 1 diabetes mellitus. "
2.	Hypoglycemia (Reactive Hypoglycemia) 11/15/2023 - "Integration of a Safety Module to Prevent Rebound Hypoglycemia in Closed-Loop Artificial Pancreas Systems." 06/01/2023 - "A closed-loop-type artificial pancreas (AP) was used to diminish the negative impact of hypoglycemia and glycemic variability during tight glycemic control. " 06/01/2023 - "No incidence of hypoglycemia occurred under the artificial pancreas. " 03/01/2022 - "Treatment using the bedside artificial pancreas enabled intensive postoperative glycemic control without hypoglycemia. " 01/01/2022 - "A closed-loop glycemic control system (artificial pancreas) has demonstrated strict safe perioperative glycemic control without hypoglycemia risk. "
3.	Diabetes Mellitus 04/30/1984 - "[Modern technologic accomplishments in the therapeutic treatment of diabetes mellitus: the artificial pancreas and micropumps]." 01/01/2007 - "One of the critical path initiatives of the Food and Drug Administration (FDA) is to accelerate the development and availability of a safe and effective artificial pancreas for the treatment of diabetes mellitus. " 10/01/2023 - "Use of Artificial Pancreas in the Management of Diabetes Mellitus: A Bibliometric Study." 09/01/1979 - "[Study of the possibility of using the "artificial pancreas" in the treatment of diabetes mellitus]." 10/01/2023 - "To describe the trends and characteristics of the worldwide scientific production on the use of artificial pancreas (AP) in the management of diabetes mellitus (DM). "
4.	Type 2 Diabetes Mellitus (MODY) 01/01/2019 - "Analysis of "Artificial Pancreas (AP) Systems for People With Type 2 Diabetes: Conception and Design of the European CLOSE Project"." 01/01/2019 - "Artificial Pancreas Systems for People With Type 2 Diabetes: Conception and Design of the European CLOSE Project." 03/01/2001 - "Insulin sensitivity indexes were assessed in patients with type 2 diabetes by hyperinsulinemic-euglycemic clamp using artificial pancreas. " 08/01/1999 - "Insulin sensitivity was measured in 11 of 17 NIDDM patients by the artificial pancreas. " 01/01/2017 - "We assessed whether fully closed-loop insulin delivery (the so-called artificial pancreas) is safe and effective compared with standard subcutaneous insulin therapy in patients with type 2 diabetes in the general ward. "
5.	Hyperglycemia 01/01/2022 - "Using an Online Disturbance Rejection and Anticipation System to Reduce Hyperglycemia in a Fully Closed-Loop Artificial Pancreas System." 01/01/2020 - "Artificial pancreas is usually used to manage hyperglycemia. " 01/01/2020 - "Perioperative hyperglycemia increases postoperative infectious complications; however, tight glycemic control using artificial pancreas can reduce them via a dual effect. " 05/01/2016 - "[MANAGEMENT OF PERIOPERATIVE HYPERGLYCEMIA USING AN ARTIFICIAL PANCREAS]." 03/01/2016 - "Tight Glycemic Control Using an Artificial Pancreas Is Useful for Surgical Patients With Uncontrolled Perioperative Hyperglycemia."

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Insulin (Novolin)
3.	Hormones (Hormone)
4.	Blood Glucose (Blood Sugar)
5.	Carbohydrates
6.	Hemoglobins (Hemoglobin)
7.	Solutions
8.	Elements
9.	Glucagon (Glukagon)
10.	pramlintide (Symlin)

Related Therapies and Procedures

1.	Therapeutics
2.	Glycemic Control
3.	Critical Care (Surgical Intensive Care)
4.	Pancreatectomy
5.	Infusion Pumps (Infusion Pump)